Abstract: A system for automatic production of radioisotopes includes an irradiation unit connectable to a cyclotron and having an electrolytic cell; a purification unit for purifying the radioisotope formed in the irradiation unit; two conduits for transferring an irradiated and electrodissolved target from the irradiation unit to the purification unit; and a central control unit for controlling both the operating units and the transfer means. The method for producing radioisotopes is such that the target carrier is not dissolved together with the irradiated target.

Abstract: A ventilation assembly for a machine for the preparation of radiopharmaceuticals. The ventilation assembly includes a suction apparatus and release apparatus for generating a circulation of air within a vacuum dispensing chamber, a product filling calibrator accommodated in the dispensing chamber and presenting a cavity accommodating a container to be filled with radiopharmaceutical, and a suction conduit adapted to connect a bottom portion of the accommodating cavity to the suction apparatus for creating a one-way flow in the accommodating cavity. Also, a machine that includes the ventilation assembly.

Abstract: A procedure for the preparation of radioisotopes consisting of a first step of electrodepositing a metallic isotope target to be irradiated on a target-holder element, a second step of irradiating the target, a third step of dissolving the target and a fourth set of purifying the radioisotope from the initial metallic isotope and from other possible radioactive and metallic impurities; the electrodeposition step in turn consisting of a dissolution operation in which the isotope to be irradiated is dissolved in a solution of HNO3 with concentration from 0.5 to 2.5 M, a pH buffering operation, and a recirculation operation, in which the solution obtained above is circulated at a rate from 0.5 to 3 within an electrolytic cell during the current output within the cell itself; the electrodeposition of the target to be irradiated occurs within the electrolytic cell during the recirculation operation.

Abstract: A procedure for the preparation of radioisotopes consisting of a first step of electrodepositing a metallic isotope target to be irradiated on a target-holder element, a second step of irradiating the target, a third step of dissolving the target and a fourth set of purifying the radioisotope from the initial metallic isotope and from other possible radioactive and metallic impurities; the electrodeposition step in turn consisting of a dissolution operation in which the isotope to be irradiated is dissolved in a solution of HNO3 with concentration from 0.5 to 2.5 M, a pH buffering operation, and a recirculation operation, in which the solution obtained above is circulated at a rate from 0.5 to 3 within an electrolytic cell during the current output within the cell itself; the electrodeposition of the target to be irradiated occurs within the electrolytic cell during the recirculation operation.

Abstract: A system for automatically producing radioisotopes, and including a target carrier; an electrodeposition unit for electrodepositing a target in the target carrier; an irradiation unit for irradiating the target in the target carrier; first transfer means for transferring the target carrier from the electrodeposition unit to the irradiation unit; an electrodissolution unit for electrodissolving the irradiated target; second transfer means for transferring the target carrier from the irradiation unit to the electrodissolution unit; a purifying unit for purifying the radioisotope of the non-reacting target and impurities; third transfer means for transferring the electrodissolved irradiated target from the electrodissolution unit to the purifying unit; and a central control unit for controlling the operating units and transfer means to automate the entire process. The electrodissolution of the irradiated target is carried out without corroding said target carrier.

Abstract: A system for automatic production of radioisotopes includes an irradiation unit connectable to a cyclotron and having an electrolytic cell; a purification unit for purifying the radioisotope formed in the irradiation unit; two conduits for transferring an irradiated and electrodissolved target from the irradiation unit to the purification unit; and a central control unit for controlling both the operating units and the transfer means. The method for producing radioisotopes is such that the target carrier is not dissolved together with the irradiated target.

Abstract: A ventilation assembly for a machine for the preparation of radiopharmaceuticals, consisting of suction means and release means for generating a circulation of air within a vacuum dispensing chamber, a product filling calibrator accommodated in the dispensing chamber and presenting a cavity accommodating a container to be filled with radiopharmaceutical, and a suction conduit adapted to connect a bottom portion of the accommodating cavity to the suction means for creating a one-way flow in the accommodating cavity.

Abstract: A double needle element for dispensing radiofluids, consists of a supporting body, in which at a first end it is made a connection cavity adapted to accommodate part of a container to be filled, and at a second end there are made two cylindrical cavities each of which is adapted to accommodate an end of a respective tube; the double needle element comprises a pair of needles fixedly accommodated within the supporting body, each of which has an output end portion accommodated within the connection cavity, and an input end connected to a respective cylindrical cavity.