Patents by Inventor Paolo Carminati

Paolo Carminati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6441039
    Abstract: Exogenous L-carnitine in the form of an equimolar amount of L-carnitine acid fumarate is administered to reduce increased volume and fluidity of stools and frequency of bowel movements relative to their usual pattern brought about by the administration of exogenous L-carnitine. Preferably nutritionally dietetically or therapeutically effective amount of L-carnitine acid fumarate is administered orally in the form of a tablet pill, capsule or powder.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: August 27, 2002
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Paolo Carminati
  • Publication number: 20010008939
    Abstract: Camptothecin derivatives of camptothecin of formula (I) 1
    Type: Application
    Filed: December 22, 2000
    Publication date: July 19, 2001
    Applicant: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A..
    Inventors: Sergio Penco, Lucio Merlini, Paolo Carminati, Franco Zunino
  • Patent number: 6245800
    Abstract: A pharmaceutical composition is described, comprising a lipid-lowering drug such as lovastatin, simvastatin, pravastatin and fluvastatin and L-carnitine or an alkanoyl L-carnitine, which, while conserving the efficacy of the lipid-lowering drug, is substantially devoid of the toxic or side effects typical of such drugs.
    Type: Grant
    Filed: September 1, 1999
    Date of Patent: June 12, 2001
    Assignee: Sigma-Tau
    Inventors: Arduino Arduini, Alessandro Peschechera, Paolo Carminati
  • Patent number: 6242457
    Abstract: Camptothecin derivatives of camptothecin of formula (I) wherein the groups R1, R2 and R3 are as defined in the description are disclosed. The compounds of formula (I) are endowed with antitumor activity and show a good therapeutic index. Processes for the preparation of the compounds of formula (I) and their use in the preparation of medicaments useful in the treatment of tumors, viral infections and antiplasmodium falciparum are also disclosed.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: June 5, 2001
    Assignees: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A., Istituo Nazionale per lo Studio e la Cura dei Tumori
    Inventors: Sergio Penco, Lucio Merlini, Paolo Carminati, Franco Zunino
  • Patent number: 5288704
    Abstract: A pharmaceutcial composition is provided for use in the prevention or treatment of viral infections caused by enveloped viruses. The composition comprises a fibroblast growth factor, a sulfated polysaccharide with antiviral activity, and one or more pharmaceutically acceptable carriers. The fibroblast growth factor may be a basic fibroblast growth factor or an analogue thereof, and the polysaccharide may be a carrageenan, heparin, dextran sulfate, pentosan polysulfate or a sulfated polysaccharides produced by marine algae belonging to the class of Rhodophyceae.
    Type: Grant
    Filed: January 31, 1992
    Date of Patent: February 22, 1994
    Assignee: Farmitalia Carlo Erba S.R.L.
    Inventors: Domenico Ungheri, Luisa Garofano, Carlo Battistini, Paolo Carminati, Guy Mazue
  • Patent number: 5089489
    Abstract: 6-substituted penem esters of formula (I): ##STR1## wherein R.sub.1 is halogen or a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, phenyl, phenoxy, benzyl or sulphonyloxy group; R.sub.2 is a C.sub.1 -C.sub.4 alkyl, benzyl diphenylmethyl ##STR2## group where A is C.sub.1 -C.sub.4 alkyl, benzyl, p-nitrobenzyl or p-methoxybenzyl; and R.sub.3 is an organic radical, are elastase inhibitors and thereby useful antiinflammatory and antidegenerative agents.
    Type: Grant
    Filed: April 5, 1990
    Date of Patent: February 18, 1992
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Marco Alpegiani, Ettore Perrone, Piergiuseppe Orezzi, Paolo Carminati, Giuseppe Cassinelli
  • Patent number: 4954493
    Abstract: 6-substituted penem esters of formula (I): ##STR1## wherein R.sub.1 is halogen or a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, phenyl, phenoxy, benzyl, or sulphonyloxy group; R.sub.2 is a C.sub.1 -C.sub.4 alkyl, benzyl diphenylmethyl ##STR2## group where A is C.sub.1 -C.sub.4 is C.sub.1 -C.sub.4 alkyl, benzyl, p-nitrobenzyl or p-methoxybenzyl; and R.sub.3 is an organic radical, are elastase inhibitors and thereby useful antiinflammatory and antidegenerative agents.
    Type: Grant
    Filed: June 14, 1988
    Date of Patent: September 4, 1990
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Marco Alpegiani, Ettore Perrone, Piergiuseppe Orezzi, Paolo Carminati, Giuseppe Cassinelli
  • Patent number: 4691019
    Abstract: The invention relates to 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula ##STR1## in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic acitivity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: September 1, 1987
    Assignee: Sanofi
    Inventors: Dino Nisato, Emilio Crisafulli, Alberto Bianchetti, Paolo Carminati
  • Patent number: 4602024
    Abstract: The invention relates to 4-(-3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula ##STR1## in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic activity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.
    Type: Grant
    Filed: July 16, 1984
    Date of Patent: July 22, 1986
    Assignee: Sanofi
    Inventors: Dino Nisato, Emilio Crisafulli, Alberto Bianchetti, Paolo Carminati
  • Patent number: 4542136
    Abstract: The present invention relates to a process for preparing 2-(1-piperazinyl) pyrimidines of formula: ##STR1## in which one of the groups T and Q represents hydrogen, a hydroxyl or lower alkanoyloxy group, and the other represents hydrogen; and X represents:a group --CO--R.sub.1a group ##STR2## an alkylene-COOY group an alkylene-CO--W group,according to which a 2-(1-piperazinyl) pyrimidine of formula: ##STR3## is reacted with a compound of formula AX in which A is selected from an atom of halogen and an activator group of the carboxylic function of the radical X.
    Type: Grant
    Filed: October 28, 1983
    Date of Patent: September 17, 1985
    Assignee: Sanofi
    Inventors: Paolo Carminati, Kathleen Biziere, Andre Hallot
  • Patent number: 4501747
    Abstract: Amides acting as histamine H.sub.2 receptors antagonists, of formula ##STR1## wherein X represents a N.fwdarw.O or C-NH-A-B group in which A is CO or SO.sub.2 and B is alkyl, phenyl, pyridyl, pyridyl 1-oxide, pyrazinyl or thienyl; their salts; process for their preparation by reacting 2-(2-guanidinothiazol-4-ylmethylthio)ethylamine with a derivative of formula ##STR2## and optional salification; and pharmaceutical compositions containing same.
    Type: Grant
    Filed: April 29, 1983
    Date of Patent: February 26, 1985
    Assignee: Sanofi
    Inventors: Dino Nisato, Sergio Boveri, Romeo Roncucci, Paolo Carminati
  • Patent number: 4489079
    Abstract: The present invention relates to a pharmaceutical composition having a peripheral antagonistic action with respect to opiates containing, as active ingredient, a haloallylate of levallorphan of formula: ##STR1## where X is chlorine, bromine or iodine, mixed with a pharmaceutical excipient.
    Type: Grant
    Filed: September 24, 1982
    Date of Patent: December 18, 1984
    Assignee: Sonofi
    Inventors: Antonina Giudice, Claude Moulineau, Luciano Manara, Paolo Carminati
  • Patent number: 4472408
    Abstract: The invention relates to 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridines of formula ##STR1## in which R represents a cyano, acetyl or cycloalkyl group of from 3 to 7 carbon atoms and Alk represents a straight or branched alkylene of from 1 to 4 carbon atoms, as well as to the salts thereof, having an anorectic activity, to a process for preparing same and to pharmaceutical compositions containing said compounds, useful in the treatment of obesity.
    Type: Grant
    Filed: March 3, 1982
    Date of Patent: September 18, 1984
    Assignee: Sanofi
    Inventors: Dino Nisato, Emilio Crisafulli, Alberto Bianchetti, Paolo Carminati
  • Patent number: 4439444
    Abstract: Amidobenzamides acting as histamine H.sub.2 receptors blocking agents, of formula ##STR1## wherein A is CO or SO.sub.2 and B is alkyl, phenyl, pyridyl, pyridyl-1-oxyde, pyrazinyl or thienyl; their salts; process for their preparation by reaching 2-(5-dimethyl-aminomethylfuran-2-ylmethylthio)ethylamine with a derivative of formula ##STR2## and optional salification and pharmaceutical compositions containing same.
    Type: Grant
    Filed: July 7, 1982
    Date of Patent: March 27, 1984
    Assignee: Sanofi
    Inventors: Dino Nisato, Sergio Boveri, Alberto Bianchetti, Romeo Roncucci, Paolo Carminati
  • Patent number: 4409228
    Abstract: The present invention relates to novel 4-amino-1-(2-pyridyl)piperidines with anorexiant action, of formula: ##STR1## in which R represents hydrogen, a halogen, a methyl group, a trifluoromethyl group, a lower alkoxy group, a trifluoromethoxy group, a 2,2,2-trifluoroethoxy group, a lower alkylthio group, a trifluoromethylthio group, a possibly substituted phenoxy group or a possibly substituted phenylthio group; to salts thereof; to a process for preparation thereof; to drugs containing same; and to intermediate products in the synthesis thereof.
    Type: Grant
    Filed: December 3, 1981
    Date of Patent: October 11, 1983
    Assignee: Sanofi
    Inventors: Dino Nisato, Paolo Carminati