Patents by Inventor Parameswara M. Reddy

Parameswara M. Reddy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for increasing the dynamic range and accuracy of binding assays
    Patent number: 6867005
    Abstract: This invention relates to methods for increasing the dynamic range and accuracy of assays in which the presence, absence, activity or concentration of a target analyte is assayed by the emission or quenching of a light signal, or by a change (i.e., an evolution or loss) of a light signal in two or more time intervals. In preferred embodiments multiple digitized images are captured at varying times, and the images analyzed to identify captured images within the dynamic range of the assay. The invention further relates to apparati capable of implementing such methods.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: March 15, 2005
    Assignee: Beckman Coulter, Inc.
    Inventors: Daniel A. Keys, Parameswara M. Reddy
  • Method and apparatus for increasing the dynamic range and accuracy of binding assays
    Publication number: 20030078737
    Abstract: This invention relates to methods for increasing the dynamic range and accuracy of assays in which the presence, absence, activity or concentration of a target analyte is assayed by the emission or quenching of a light signal, or by a change (i.e., an evolution or loss) of a light signal in two or more time intervals. In preferred embodiments multiple digitized images are captured at varying times, and the images analyzed to identify captured images within the dynamic range of the assay. The invention further relates to apparati capable of implementing such methods.
    Type: Application
    Filed: October 24, 2001
    Publication date: April 24, 2003
    Inventors: Daniel A. Keys, Parameswara M. Reddy
  • Methods and reagents for cleaving and deprotecting oligonucleotides
    Patent number: 5518651
    Abstract: Disclosed are reagents of methods for cleaving and deprotecting insolubilized and protected synthetic oligonucleotides. In a particularly preferred embodiment, the reagent comprises methylamine and t-butylamine.
    Type: Grant
    Filed: June 8, 1994
    Date of Patent: May 21, 1996
    Assignee: Beckman Instruments, Inc.
    Inventors: Parameswara M. Reddy, Naeem B. Hanna
  • N.sup.4 - acylated cytidinyl compounds useful in oligonucleotide synthesis
    Patent number: 5428148
    Abstract: Disclosed herein are protecting groups for exocyclic amino groups of the bases adenine, guanine and cytosine for use in the synthesis of oligonucleotides, the protecting groups being represented by the formula: --CO-- (CH.sub.2).sub.0-9 --CH.sub.3. In a particularly preferred embodiment, the base cytosine is protected with acetyl (--CO--CH.sub.3), and the oligonucleotide incorporating said protected cytosine is subjected to a cleavage/deprotection reagent comprising at least one straight chain alkylamine having from 1 to about 10 carbon atoms.
    Type: Grant
    Filed: April 24, 1992
    Date of Patent: June 27, 1995
    Assignee: Beckman Instruments, Inc.
    Inventors: Parameswara M. Reddy, Naeem B. Hanna
  • Methods and reagents for cleaving and deprotecting oligonucleotides
    Patent number: 5348868
    Abstract: Disclosed are reagents of methods for cleaving and deprotecting insolubilized and protected synthetic oligonucleotides. In a particularly preferred embodiment, the reagent comprises methylamine and t-butylamine.
    Type: Grant
    Filed: April 24, 1992
    Date of Patent: September 20, 1994
    Assignee: Beckman Instruments, Inc.
    Inventors: Parameswara M. Reddy, Naeem B. Hanna