Patents by Inventor Partha Neogi
Partha Neogi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7781464Abstract: The present invention relates to novel heterocyclic diphenyl ether and diphenyl amine compounds, derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and pharmaceutically acceptable solvates thereof and pharmaceutically acceptable compositions containing these singly or in combination. The compounds of the present invention are effective in lowering blood glucose, serum insulin, free fatty acids, cholesterol and triglyceride levels and are useful in the treatment and/or prophylaxis of diabetes. The compounds of the present invention are effective in treatment of obesity, inflammation, autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and immunological diseases, including the treatment of cancer. Furthermore, the compounds are useful for the treatment of disorders associated with insulin resistance.Type: GrantFiled: February 21, 2006Date of Patent: August 24, 2010Assignee: Bexel Pharmaceuticals, Inc.Inventors: Partha Neogi, Bishwajit Nag, Debendranath Dey, Abhijeet Nag, Birendra Kumar Bhattacharya, Vinod Kumar Singh, Surendradoss Jayakumar
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Patent number: 7718682Abstract: Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.Type: GrantFiled: April 2, 2008Date of Patent: May 18, 2010Assignee: Theracos, Inc.Inventors: Partha Neogi, Debendranath Dey, Satyanarayana Medicherla, Bishwagit Nag, Arthur Lee
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Patent number: 7521465Abstract: Novel diphenyl ether derivatives are provided that exhibit activity useful for reducing glucose, cholesterol, and/or triglyceride levels in plasma, and for treatment of obesity, inflammation, immunological diseases, autoimmune diseases, diabetes and disorders associated with insulin resistance.Type: GrantFiled: March 31, 2005Date of Patent: April 21, 2009Assignee: Bexel Pharmaceuticals, Inc.Inventors: Bishwajit Nag, Abhijeet Nag, Debendranath Dey, Shiv Kumar Agarwal, Partha Neogi, Gaddam Om Reddy, Sangamesh Badiger, Gajendra Singh, Surendra Kumar Pandey, Santhanagopalan Chithra
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Patent number: 7521466Abstract: Novel dipeptide ethers are effective for lowering blood glucose, serum insulin, free fatty acids, cholesterol and triglyceride levels. The dipeptide ethers are also useful for the treatment and/or prophylaxis of diabetes, obesity, inflammation and autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.Type: GrantFiled: May 4, 2006Date of Patent: April 21, 2009Assignee: Bexel Pharmaceuticals, Inc.Inventors: Bishwajit Nag, Abhijeet Nag, Debendranath Dey, Partha Neogi, Shiv Kumar Agarwal, Surendra Kumar Pandey
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Publication number: 20090069313Abstract: The present invention provides a new medical use for the compounds of the formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions, metabolites and prodrugs thereof, as MAO-A inhibitors. Also included is a method for prophylaxis and treatment of mental disorders such as depression, in a mammal, comprising administering an effective amount of a compound of formula (I). These compounds are also effective in treating a disease, condition or disorder such as weight loss, obesity, bulimia, depression, bipolar disorders, psychoses, schizophrenia, behaviors, alcoholism, tobacco abuse, memory loss, Alzheimer's disease, dementia of aging, seizure disorders, epilepsy, attention deficit disorder, and Parkinson's disease, which is modulated by a cannabinoid receptor antagonist.Type: ApplicationFiled: September 6, 2007Publication date: March 12, 2009Applicant: ORCHID RESEARCH LABORATORIES LTD.Inventors: Debendranath Dey, Gajendra Singh, Partha Neogi, Uma Ramachandran, Chithra Santhanagopalan
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Publication number: 20080319031Abstract: The present invention relates to novel tyrosine derivatives of formula (I), their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The present invention more particularly provides novel tyrosine derivatives of the general formula (I).Type: ApplicationFiled: March 10, 2006Publication date: December 25, 2008Inventors: Surendrakumar Satyanarayan Pandey, Shiv Kumar Agarwal, Gajendra Singh, Santhanagopalan Chithra, Sangmesh Badiger, Bishwajit Nag, Debendranath Dey, Abhijeet Nag, Partha Neogi
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Publication number: 20080293949Abstract: Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.Type: ApplicationFiled: April 2, 2008Publication date: November 27, 2008Applicant: Theracos, Inc.Inventors: Partha Neogi, Debendranath Dey, Satyanarayana Medicherla, Bishwajit Nag, Arthur Lee
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Patent number: 7456292Abstract: Novel hydroxamic acid containing amino acid derivatives are provided that are useful for treatment of inflammation, inflammatory and immunological diseases; lowering blood glucose, serum insulin, free fatty acids, cholesterol and triglyceride levels; and for treatment or prophylaxis of metabolic disorders.Type: GrantFiled: June 30, 2005Date of Patent: November 25, 2008Assignee: Bexel Pharmaceuticals, Inc.Inventors: Partha Neogi, Debendranath Dey, Abjiheet Nag, Sujata Neogi, Bishwajit Nag
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Publication number: 20080261981Abstract: Novel amino acid derivatives are provided that are useful for management of disorders such as obesity and immunological diseases. The derivatives are also useful in lowering blood glucose levels in hyperglycemic disorders and for treating related disorders such as body weight gain, elevated free fatty acid, cholesterol and triglyceride levels and other disorder exacerbated by obesity.Type: ApplicationFiled: June 3, 2008Publication date: October 23, 2008Inventors: DEBENDRANATH DEY, Abjiheet Nag, Bindu Pandey, Preeti Balse, Partha Neogi, Bishwajit Nag
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Publication number: 20080200521Abstract: Novel hydroxamic acid containing amino acid derivatives are provided that are useful for treatment of inflammation, inflammatory and immunological diseases; lowering blood glucose, serum insulin, free fatty acids, cholesterol and triglyceride levels; and for treatment or prophylaxis of metabolic disorders.Type: ApplicationFiled: January 3, 2008Publication date: August 21, 2008Inventors: Partha Neogi, Debendranath Dey, Abjiheet Nag, Sujata Neogi, Bishwajit Nag
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Publication number: 20080188654Abstract: Novel acyl urea, thiourea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering blood glucose levels in animal models of Type II diabetes mellitus. The compounds are disclosed as useful for a variety of treatments including the treatment of diabetes mellitus, insulin resistance, inflammation, inflammatory, diseases, immunological diseases and cancer.Type: ApplicationFiled: December 20, 2007Publication date: August 7, 2008Applicant: Theracos, Inc.Inventors: Partha Neogi, Debedranath Dey, Joseph C. Fuller, Liang Chen, Ta-Kai Li
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Patent number: 7407978Abstract: Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.Type: GrantFiled: October 8, 2002Date of Patent: August 5, 2008Assignee: Theracos, Inc.Inventors: Partha Neogi, Debendranath Dey, Satyanarayana Medicheria, Bishwajit Nag, Arthur Lee
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Publication number: 20080175795Abstract: Novel amino acid derivatives are provided that are useful for management of disorders such as obesity and immunological diseases. The derivatives are also useful in lowering blood glucose levels in hyperglycemic disorders and for treating related disorders such as body weight gain, elevated free fatty acid, cholesterol and triglyceride levels and other disorder exacerbated by obesity.Type: ApplicationFiled: January 3, 2008Publication date: July 24, 2008Inventors: Partha Neogi, Debendranath Dey, Abjiheet Nag, Bindu Pandey, Preeti Balse, Bishwajit Nag
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Patent number: 7399786Abstract: Novel amino acid derivatives are provided that are useful for management of disorders such as obesity and immunological diseases. The derivatives are also useful in lowering blood glucose levels in hyperglycemic disorders and for treating related disorders such as body weight gain, elevated free fatty acid, cholesterol and triglyceride levels and other disorder exacerbated by obesity.Type: GrantFiled: June 30, 2005Date of Patent: July 15, 2008Assignee: Bexel Pharmaceuticals, Inc.Inventors: Debendranath Dey, Abjiheet Nag, Bindu Pandey, Preeti Balse, Partha Neogi, Bishwajit Nag
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Publication number: 20080108825Abstract: Novel acyl urea, thiourea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering blood glucose levels in animal models of Type II diabetes mellitus. The compounds are disclosed as useful for a variety of treatments including the treatment of diabetes mellitus, insulin resistance, inflammation, inflammatory, diseases, immunological diseases and cancer.Type: ApplicationFiled: December 20, 2007Publication date: May 8, 2008Applicant: Theracos, Inc.Inventors: Partha Neogi, Debedranath Dey, Joseph Fuller, Liang Chen, Ta-Kai Li
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Publication number: 20080103302Abstract: Novel acyl urea, thiourea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering blood glucose levels in animal models of Type II diabetes mellitus. The compounds are disclosed as useful for a variety of treatments including the treatment of diabetes mellitus, insulin resistance, inflammation, inflammatory, diseases, immunological diseases and cancer.Type: ApplicationFiled: December 20, 2007Publication date: May 1, 2008Applicant: Theracos, Inc.Inventors: Partha Neogi, Debedranath Dey, Joseph Fuller, Liang Chen, Ta-Kai Li
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Patent number: 7323496Abstract: Novel acyl urea, thiourea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering blood glucose levels in animal models of Type II diabetes mellitus. The compounds are disclosed as useful for a variety of treatments including the treatment of diabetes mellitus, insulin resistance, inflammation, inflammatory diseases, immunological diseases and cancer.Type: GrantFiled: May 7, 2003Date of Patent: January 29, 2008Assignee: Theracos, Inc.Inventors: Partha Neogi, Debedranath Dey, Joseph Fuller, Liang Chen, Ta-Kai Li
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Publication number: 20070259961Abstract: Novel acyl urea, thiourea, carbamate, thiocarbamate and related compounds are provided which are effective in inhibiting the cytokine-mediated inflammatory response in cultured cells, in ameliorating bone destruction in an animal model of arthritis and in lowering blood glucose levels in animal models of Type II diabetes mellitus. The compounds are disclosed as useful for a variety of treatments including the treatment of diabetes mellitus, insulin resistance, inflammation, inflammatory diseases, immunological diseases and cancer.Type: ApplicationFiled: May 7, 2003Publication date: November 8, 2007Inventors: Partha Neogi, Debedranath Dey, Joseph Fuller, Liang Chen, Ta-Kai Li
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Patent number: 7202366Abstract: Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. In contrast to previously reported thiazolidinedione compounds, known to lower leptin levels, the present compounds increase leptin levels and have no known liver toxicity. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.Type: GrantFiled: March 25, 2004Date of Patent: April 10, 2007Assignee: Theracos, Inc.Inventors: Bishwajit Nag, Debendranath Dey, Satyanarayana Medicherla, Partha Neogi
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Publication number: 20070037863Abstract: Novel dipeptide ethers are effective for lowering blood glucose, serum insulin, free fatty acids, cholesterol and triglyceride levels. The dipeptide ethers are also useful for the treatment and/or prophylaxis of diabetes, obesity, inflammation and autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.Type: ApplicationFiled: May 4, 2006Publication date: February 15, 2007Inventors: Bishwajit Nag, Abhijeet Nag, Debendranath Dey, Partha Neogi, Shiv Agarwal, Surendra Pandey