Patents by Inventor Pascal GAYET

Pascal GAYET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10857242
    Abstract: A fluorescent tracer for targeting tumors, comprises: at least one first fluorophore fluorescing in a range of wavelengths of between 700 and 1000 nm, a targeting assembly comprising at least two identical targeting molecules, and a cyclic oligopeptide: configured so as to define a mean plane defining a first upper face and a second lower face, comprising at least one first lysine amino acid residue on the second lower face, the targeting molecules being fixed to the first upper face of the mean plane, the fluorophore being fixed to the second lower face of the mean plane via a spacer arm connecting a carbon of the sequence of the at least three double bonds and the lysine amino acid residue of the oligopeptide.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: December 8, 2020
    Assignee: FLUOPTICS
    Inventor: Pascal Gayet
  • Publication number: 20180147303
    Abstract: A fluorescent tracer for targeting tumors, comprises: at least one first fluorophore fluorescing in a range of wavelengths of between 700 and 1000 nm, a targeting assembly comprising at least two identical targeting molecules, and a cyclic oligopeptide: configured so as to define a mean plane defining a first upper face and a second lower face, comprising at least one first lysine amino acid residue on the second lower face, the targeting molecules being fixed to the first upper face of the mean plane, the fluorophore being fixed to the second lower face of the mean plane via a spacer arm connecting a carbon of the sequence of the at least three double bonds and the lysine amino acid residue of the oligopeptide.
    Type: Application
    Filed: May 24, 2016
    Publication date: May 31, 2018
    Inventor: Pascal GAYET
  • Publication number: 20180140723
    Abstract: A fluorescent tracer comprises: a RAFT template, comprising the residues: Glycine-Proline-Lysine-Alanine-Lysine-Glycine-Proline-Lysine-Lysine-Lysine and having a mean plane defining an upper face having four lysine residues and a lower face having one lysine residue, four identical targeting molecules comprising the amino acids: Arginine-Glycine-Aspartic acid-Phenylalanine-Lysine (RGDKf), each of the molecules being fixed to a different lysine residue of the first upper face via an oxime bond, and a fluorophore S0456 fixed to the lower face of the mean plane via a spacer arm connecting the central carbon of the sequence of double bonds of the fluorophore and the lysine amino acid of the lower face of the decapeptide via an amide bond, the spacer arm being 5-(4-hydroxyphenyl)pentanoic acid.
    Type: Application
    Filed: May 24, 2016
    Publication date: May 24, 2018
    Inventor: Pascal GAYET