Abstract: The invention provides for a steerable guidewire for insertion into a body cavity, characterized in that is comprises an elongated body defining a longitudinally-arranged lumen comprising i) a proximal end portion and ii) a distal end portion comprising a spatially reconfigurable portion and a tip; a pull wire located along said lumen and affixed to said distal end portion and to said proximal end; an actuation region located on said proximal end portion adapted to impart a tension force on the pull wire resulting in a compression force to the spatially reconfigurable region; and an intermediate region tubular element on said body located between said spatially reconfigurable portion and said proximal end.

Abstract: The present invention concerns an organic cavity injection device including an injection cannula for injecting a photo-activatable substance inside an organic cavity; at least one element or a plurality of elements configured to control the removal of a resident substance from the organic cavity and simultaneously prevent removal of the non-activated photo-activatable substance from the organic cavity; and an optical waveguide for providing electromagnetic radiation inside the organic cavity to the photo-activatable substance to photoactive the photo-activatable substance inside the organic cavity.

Abstract: The present invention concerns an organic cavity injection device including an injection cannula for injecting a photo-activatable substance inside an organic cavity; at least one element or a plurality of elements configured to control the removal of a resident substance from the organic cavity and simultaneously prevent removal of the non-activated photo-activatable substance from the organic cavity; and an optical waveguide for providing electromagnetic radiation inside the organic cavity to the photo-activatable substance to photoactive the photo-activatable substance inside the organic cavity.