Patents by Inventor Pascal Spincemaille
Pascal Spincemaille has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240012080Abstract: Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure.Type: ApplicationFiled: September 25, 2023Publication date: January 11, 2024Applicant: Cornell UniversityInventors: Yi Wang, Zhe Liu, Jinwei Zhang, Qihao Zhang, Junghun Cho, Pascal Spincemaille
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Publication number: 20230320611Abstract: Quantitative susceptibility mapping methods, systems and computer-accessible medium generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian inference approach, which minimizes a cost function comprising of a data fidelity term and regularization terms. The data fidelity term is constructed directly from the multiecho complex magnetic resonance imaging data. The regularization terms include a prior constructed from matching structures or information content in known morphology, and a prior constructed from regions of low susceptibility contrasts characterized on image features. The quantitative susceptibility map can be determined by minimizing the cost function that involves nonlinear functions in modeling the obtained signals, and the corresponding inverse problem is solved using nonconvex optimization using a scaling approach or deep neural network.Type: ApplicationFiled: August 19, 2021Publication date: October 12, 2023Applicant: Cornell UniversityInventors: Yi Wang, Yan Wen, Ramin Jafari, Thanh Nguyen, Pascal Spincemaille, Junghun Cho, Qihao Zhang
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Patent number: 11782112Abstract: Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure.Type: GrantFiled: May 28, 2020Date of Patent: October 10, 2023Assignee: Cornell UniversityInventors: Yi Wang, Zhe Liu, Jinwei Zhang, Qihao Zhang, Junghun Cho, Pascal Spincemaille
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Publication number: 20230160987Abstract: Exemplary quantitative susceptibility mapping methods, systems and computer-accessible medium can be provided to generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian inference approach, which minimizes a cost function consisting of a data fidelity term and two regularization terms. The data fidelity term is constructed directly from the complex magnetic resonance imaging data. The first prior is constructed from matching structures or information content in known morphology. The second prior is constructed from a region having an approximately homogenous and known susceptibility value and a characteristic feature on anatomic images. The quantitative susceptibility map can be determined by minimizing the cost function. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining magnetic susceptibility information associated with at least one structure.Type: ApplicationFiled: January 9, 2023Publication date: May 25, 2023Applicant: CORNELL UNIVERSITYInventors: Yi Wang, Zhe Liu, Youngwook Kee, Alexey Dimov, Yan Wen, Jingwei Zhang, Pascal Spincemaille
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Patent number: 11635480Abstract: Exemplary quantitative susceptibility mapping methods, systems and computer-accessible medium can be provided to generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian inference approach, which minimizes a cost function consisting of a data fidelity term and two regularization terms. The data fidelity term is constructed directly from the complex magnetic resonance imaging data. The first prior is constructed from matching structures or information content in known morphology. The second prior is constructed from a region having an approximately homogenous and known susceptibility value and a characteristic feature on anatomic images. The quantitative susceptibility map can be determined by minimizing the cost function. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining magnetic susceptibility information associated with at least one structure.Type: GrantFiled: January 6, 2021Date of Patent: April 25, 2023Assignee: CORNELL UNIVERSITYInventors: Yi Wang, Zhe Liu, Youngwook Kee, Alexey Dimov, Yan Wen, Jingwei Zhang, Pascal Spincemaille
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Publication number: 20220229140Abstract: Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure.Type: ApplicationFiled: May 28, 2020Publication date: July 21, 2022Applicant: Cornell University Center for Technology Licensing (CTL)Inventors: Yi WANG, Zhe LIU, Jinwei ZHANG, Qihao ZHANG, Junghun CHO, Pascal SPINCEMAILLE
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Publication number: 20210132170Abstract: Exemplary quantitative susceptibility mapping methods, systems and computer-accessible medium can be provided to generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian inference approach, which minimizes a cost function consisting of a data fidelity term and two regularization terms. The data fidelity term is constructed directly from the complex magnetic resonance imaging data. The first prior is constructed from matching structures or information content in known morphology. The second prior is constructed from a region having an approximately homogenous and known susceptibility value and a characteristic feature on anatomic images. The quantitative susceptibility map can be determined by minimizing the cost function. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining magnetic susceptibility information associated with at least one structure.Type: ApplicationFiled: January 6, 2021Publication date: May 6, 2021Applicant: CORNELL UNIVERSITYInventors: Yi Wang, Zhe Liu, Youngwook Kee, Alexey Dimov, Yan Wen, Jingwei Zhang, Pascal Spincemaille
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Patent number: 10890641Abstract: Exemplary quantitative susceptibility mapping methods, systems and computer-accessible medium can be provided to generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian inference approach, which minimizes a cost function consisting of a data fidelity term and two regularization terms. The data fidelity term is constructed directly from the complex magnetic resonance imaging data. The first prior is constructed from matching structures or information content in known morphology. The second prior is constructed from a region having an approximately homogenous and known susceptibility value and a characteristic feature on anatomic images. The quantitative susceptibility map can be determined by minimizing the cost function. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining magnetic susceptibility information associated with at least one structure.Type: GrantFiled: April 3, 2018Date of Patent: January 12, 2021Assignee: Cornell UniversityInventors: Yi Wang, Zhe Liu, Youngwook Kee, Alexey Dimov, Yan Wen, Jingwei Zhang, Pascal Spincemaille
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Publication number: 20180321347Abstract: Exemplary quantitative susceptibility mapping methods, systems and computer-accessible medium can be provided to generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian inference approach, which minimizes a cost function consisting of a data fidelity term and two regularization terms. The data fidelity term is constructed directly from the complex magnetic resonance imaging data. The first prior is constructed from matching structures or information content in known morphology. The second prior is constructed from a region having an approximately homogenous and known susceptibility value and a characteristic feature on anatomic images. The quantitative susceptibility map can be determined by minimizing the cost function. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can he provided for determining magnetic susceptibility information associated with at least one structure.Type: ApplicationFiled: April 3, 2018Publication date: November 8, 2018Inventors: Yi Wang, Zhe Liu, Youngwook Kee, Alexey Dimov, Yan Wen, Jingwei Zhang, Pascal Spincemaille
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Patent number: 8781197Abstract: A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object.Type: GrantFiled: April 28, 2009Date of Patent: July 15, 2014Assignee: Cornell UniversityInventors: Yi Wang, Ludovic de Rochefort, Bryan Kressler, Tian Liu, Pascal Spincemaille
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Patent number: 8200311Abstract: Described is a robust electrocardiogram (ECG) ordering technique of k-space for breath hold contrast enhanced magnetic resonance angiography (CE-MRA) that acquires the central part of k-space in a motion-free portion of diastole and fills in from the periphery of k-space at all other times. To make maximal use of the contrast enhancement, data is acquired continuously even when the ECG signal is lost. The ECG signal is monitored in real time. The ECG ordering technique allows a flexible acquisition matrix and is robust against ECG signal imperfections. The ECG ordering technique allows thoracic and pulmonary magnetic resonance angiography with a higher resolution when compared to the conventional gated sequence.Type: GrantFiled: April 20, 2007Date of Patent: June 12, 2012Assignee: Cornell Research Foundation, Inc.Inventors: Pascal Spincemaille, Yi Wang, Martin R. Prince
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Patent number: 7941204Abstract: Methods of acquiring magnetic resonance imaging (MRI) data for angiography. The present invention includes novel magnetization preparation schemes where the navigator and fat saturation pulses are executed in steady state after the preparatory pulses in order to minimize the delay between the magnetization preparation and the image echoes. The present invention also provides for improved methods of contrast-enhanced MRI where data are collected along non-linear trajectories through k-space and may also involve novel view ordering. In addition, the present methods employ novel motion corrections that minimize motion artifacts. The present invention further provides novel methods of self-calibrated sensitivity-encoded parallel imaging that allow for accurate and rapid scanning of subjects.Type: GrantFiled: November 16, 2005Date of Patent: May 10, 2011Inventors: Yi Wang, Pascal Spincemaille, Thanh D. Nguyen
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Publication number: 20110044524Abstract: A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object.Type: ApplicationFiled: April 28, 2009Publication date: February 24, 2011Applicant: CORNELL UNIVERSITYInventors: Yi Wang, Ludovic de Rochefort, Bryan Kressler, Tian Liu, Pascal Spincemaille
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Publication number: 20070287907Abstract: Described is a robust electrocardiogram (ECG) ordering technique of k-space for breath hold contrast enhanced magnetic resonance angiography (CE-MRA) that acquires the central part of k-space in a motion-free portion of diastole and fills in from the periphery of k-space at all other times. To make maximal use of the contrast enhancement, data is acquired continuously even when the ECG signal is lost. The ECG signal is monitored in real time. The ECG ordering technique allows a flexible acquisition matrix and is robust against ECG signal imperfections. The ECG ordering technique allows thoracic and pulmonary magnetic resonance angiography with a higher resolution when compared to the conventional gated sequence.Type: ApplicationFiled: April 20, 2007Publication date: December 13, 2007Applicant: CORNELL RESEARCH FOUNDATION, INC.Inventors: Pascal Spincemaille, Yi Wang, Martin R. Prince