Patents by Inventor Pascale Delangle

Pascale Delangle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclodecapeptide compounds for use as drugs
    Patent number: 9856294
    Abstract: The invention relates to novel cyclodecapeptide compounds having formula (I) for use as drugs and, more specifically, for use in the diagnosis, prevention and/or treatment of neurodegenerative diseases, such as Wilson's disease and Alzheimer's disease, and for use in the diagnosis, prevention and/or treatment of poisoning with metal ions, such as copper and mercury ions. The invention also relates to pharmaceutical compositions comprising at least one compound having formula (I) as an active principle.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: January 2, 2018
    Assignees: Commissariat A L'Energie Atomique Et Aux Energies Alternatives, Universite Joseph Fourier
    Inventors: Pascale Delangle, Anaïs Pujol, Pascal Dumy, Olivier Renaudet, Michel Ferrand
  • Uranium-chelating peptides derived from EF-hand calcium-binding motif useful for uranium biodetection and biodecontamination
    Patent number: 9845343
    Abstract: Uranium-chelating polypeptides comprising at least one helix-loop-helix calcium-binding (EF-hand) motif which comprises a deletion of at least two amino acid in the 12-amino-acid calcium-binding loop sequence, and their use for uranium biodetection and biodecontamination.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: December 19, 2017
    Assignee: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Romain Pardoux, Sandrine Sauge-Merle, David Lemaire, Catherine Berthomieu, Philippe Guilbaud, Pascale Delangle, Nicolas Bremond, Maria-Rosa Beccia
  • New uranium-chelating peptides derived from EF-hand calcium-binding motif useful for uranium biodetection and biodecontamination
    Publication number: 20160130316
    Abstract: Uranium-chelating polypeptides comprising at least one helix-loop-helix calcium-binding (EF-hand) motif which comprises a deletion of at least two amino acid in the 12-amino-acid calcium-binding loop sequence, and their use for uranium biodetection and biodecontamination.
    Type: Application
    Filed: March 28, 2014
    Publication date: May 12, 2016
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Romain PARDOUX, Sandrine SAUGE-MERLE, David LEMAIRE, Catherine BERTHOMIEU, Philippe GUILBAUD, Pascale DELANGLE, Nicolas BREMOND, Maria-Rosa BECCIA
  • Novel Cyclodecapeptide Compounds For Use As Drugs
    Publication number: 20130251639
    Abstract: The invention relates to novel cyclodecapeptide compounds having formula (I) for use as drugs and, more specifically, for use in the diagnosis, prevention and/or treatment of neurodegenerative diseases, such as Wilson's disease and Alzheimer's disease, and for use in the diagnosis, prevention and/or treatment of poisoning with metal ions, such as copper and mercury ions. The invention also relates to pharmaceutical compositions comprising at least one compound having formula (I) as an active principle.
    Type: Application
    Filed: May 17, 2011
    Publication date: September 26, 2013
    Applicant: UNIVERSITE JOSEPH FOURIER
    Inventors: Pascale Delangle, Anaïs Pujol, Pascal Dumy, Olivier Renaudet, Michel Ferrand
  • Chelating agents of metal ions, their methods of preparation and their applications
    Patent number: 8148359
    Abstract: The present invention relates to compounds that can be used as metal-ion-chelating agents or as depolluting agents, corresponding to general formula (I) below: and also to precursor compounds of formula (II) and labelled compounds of formula (III) deriving from the compounds of formula (I). The present invention also relates to the use of the compounds (I), (II) or (III) as a medicament, and also the use thereof for the diagnosis, prevention and treatment of neurodegenerative diseases such as Wilson's disease and Alzheimer's disease.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: April 3, 2012
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Pascale Delangle, Christelle Gateau, Anaïs Pujol
  • CHELATING AGENTS OF METAL IONS, THEIR METHODS OF PREPARATION AND THEIR APPLICATIONS
    Publication number: 20100234338
    Abstract: The present invention relates to compounds that can be used as metal-ion-chelating agents or as depolluting agents, corresponding to general formula (I) below: and also to precursor compounds of formula (II) and labelled compounds of formula (III) deriving from the compounds of formula (I). The present invention also relates to the use of the compounds (I), (II) or (III) as a medicament, and also the use thereof for the diagnosis, prevention and treatment of neurodegenerative diseases such as Wilson's disease and Alzheimer's disease.
    Type: Application
    Filed: March 13, 2009
    Publication date: September 16, 2010
    Inventors: Pascale Delangle, Christelle Gateau, Anais Pujol