Patents by Inventor PASCALINE LECORCHE

PASCALINE LECORCHE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR CANCER IMAGING AND RADIOTHERAPY
    Publication number: 20240100204
    Abstract: The present invention relates to a conjugated compound comprising a marker M pharmaceutically acceptable, and a peptide or pseudo-peptide P having at most 30 amino acid residues and able to bind the Low-Density Lipoprotein Receptor (LDLR) and to its use in a method of labelling and/or detecting and/or treating cancerous cells in a subject by administration of the conjugated compound to the subject an analysis of the presence and/or the amount of marker.
    Type: Application
    Filed: July 28, 2023
    Publication date: March 28, 2024
    Inventors: CÉDRIC MALICET, PASCALINE LECORCHE, JONATHAN NOWAK, MARION DAVID, JAMAL TEMSAMANI, MICHEL KHRESTCHATISKY
  • TRANSFERRIN RECEPTOR-BINDING MOLECULES, CONJUGATES THEREOF AND THEIR USES
    Publication number: 20230414780
    Abstract: The invention relates to Variable Domain of Camelid Heavy Chain-only (VHH) molecules which bind TfR, conjugate compounds comprising such VHH molecules, and the uses thereof e.g., to transport molecules of pharmaceutical or diagnostic interest into cells and in organs, in pathological conditions including cancer.
    Type: Application
    Filed: June 22, 2023
    Publication date: December 28, 2023
    Inventors: ROMY COHEN, MARION DAVID, GUILLAUME JACQUOT, JAMAL TEMSAMANI, PASCALINE LECORCHE, MICHEL KHRESTCHATISKY
  • Compositions and methods for cancer imaging and radiotherapy
    Patent number: 11712486
    Abstract: The present invention relates to a conjugated compound comprising a marker M pharmaceutically acceptable, and a peptide or pseudo-peptide P having at most 30 amino acid residues and able to bind the Low-Density Lipoprotein Receptor (LDLR) and to its use in a method of labelling and/or detecting and/or treating cancerous cells in a subject by administration of the conjugated compound to the subject an analysis of the presence and/or the amount of marker.
    Type: Grant
    Filed: January 30, 2018
    Date of Patent: August 1, 2023
    Assignees: VECT-HORUS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX-MARSEILLE
    Inventors: Cédric Malicet, Pascaline Lecorche, Jonathan Nowak, Marion David, Jamal Temsamani, Michel Khrestchatisky
  • COMPOSITIONS AND METHODS FOR CANCER IMAGING AND RADIOTHERAPY
    Publication number: 20190351079
    Abstract: The present invention relates to a conjugated compound comprising a marker M pharmaceutically acceptable, and a peptide or pseudo-peptide P having at most 30 amino acid residues and able to bind the Low-Density Lipoprotein Receptor (LDLR) and to its use in a method of labelling and/or detecting and/or treating cancerous cells in a subject by administration of the conjugated compound to the subject an analysis of the presence and/or the amount of marker.
    Type: Application
    Filed: January 30, 2018
    Publication date: November 21, 2019
    Inventors: CÉDRIC MALICET, PASCALINE LECORCHE, JONATHAN NOWAK, MARION DAVID, JAMAL TEMSAMANI, MICHEL KHRESTCHATISKY
  • Activated neurotensin molecules and the uses thereof
    Patent number: 9821072
    Abstract: The present invention relates to activated neurotensin, pharmaceutical compositions comprising the same, and the uses thereof. The compounds and compositions of the invention may be used, e.g., to reduce body temperature, attenuate or halt seizures, reduce excitotoxicity, promote neuroprotection, reduce neuroinflammation and aberrant axonal sprouting or reduce pain.
    Type: Grant
    Filed: January 19, 2015
    Date of Patent: November 21, 2017
    Assignees: VECT-HORUS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Guillaume Jacquot, Pascaline Lecorche, Michel Khrestchatisky
  • ACTIVATED NEUROTENSIN MOLECULES AND THE USES THEREOF
    Publication number: 20160354480
    Abstract: The present invention relates to activated neurotensin, pharmaceutical compositions comprising the same, and the uses thereof. The compounds and compositions of the invention may be used e.g., to reduce body temperature, attenuate or halt seizures, reduce excitotoxicity, promote neuroprotection, reduce neuroinflammation and aberrant axonal sprouting or reduce pain.
    Type: Application
    Filed: January 19, 2015
    Publication date: December 8, 2016
    Inventors: GUILLAUME JACQUOT, PASCALINE LECORCHE, MICHEL KHRESTCHATISKY