Patents by Inventor Patrice Courvalin

Patrice Courvalin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR DETECTING MICROORGANISMS
    Publication number: 20130029863
    Abstract: The invention relates to the diagnostic field and to the characterization of antibiotic-resistant bacteria in a sample by detecting specific nucleotides in the CMY-2 gene.
    Type: Application
    Filed: September 30, 2010
    Publication date: January 31, 2013
    Applicants: Institut Pasteur, Assistance Publique - Hopitaux de Paris
    Inventors: Etienne Ruppe, Antoine Andremont, Raymond Ruimy, Patrice Courvalin, Sylvie Bremont
  • Polypeptides implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria, nucleotide sequence coding for these polypeptides and use for diagnosis
    Patent number: 6916906
    Abstract: The invention relates to a composition of polypeptides, characterized in that it contains at least one protein or part of a protein selected from the sequences of amino acids identified in the list of the sequences as SEQ ID NO 1 (VanH), SEQ ID NO 2 (VanA).
    Type: Grant
    Filed: July 20, 1999
    Date of Patent: July 12, 2005
    Assignee: Institut Pasteur
    Inventors: Michel Arthur, Sylvie Dukta-Malen, Catherine Molinas, Patrice Courvalin
  • Polypeptides implicated in the expression of resistance to glycopeptides, in particular in Gram-positive bacteria, nucleotide sequence coding for these polypeptides and use for diagnosis
    Publication number: 20050112641
    Abstract: The invention relates to a composition of polypeptides, characterized in that it contains at least one protein or part of a protein selected from the sequences of amino acids identified in the list of the sequences as SEQ ID NO 1 (VanH), SEQ ID NO 2 (VanA), SEQ ID NO 3 (VanX) or SEQ ID NO 19 (VanC), or any protein or part of a protein recognized by the antibodies directed against VanH, VanA, VanX or VanC, or any protein or part of a protein encoded in a sequence hybridizing with one of the nucleotide sequences identified in the list of the sequences as SEQ ID NO 8, SEQ ID NO 9 or SEQ ID NO 10 or with one of the following sequences V1 or V2 under stringent or only slightly stringent conditions: V1: GGX GAA GAT GGX TCX TTX CAA GGX ??G ??C AG C ??G A V2: AAT ACX ATX CCX GGX TTT AC ??C T ??C C The invention also relates to the nucleotide sequences coding for these polypeptides as well as their utilization for the diagnosis of resistance to the glycopeptides.
    Type: Application
    Filed: September 30, 2004
    Publication date: May 26, 2005
    Applicant: INSTITUT PASTEUR
    Inventors: Michel Arthur, Sylvie Dukta-Malen, Catherine Molinas, Patrice Courvalin
  • Nucleic acids encoding a protein conferring an inducible resistance to glycopeptide, particularly in gram-positive bacteria
    Patent number: 6569622
    Abstract: The invention relates to a protein VanB involved, in Gram-positive bacteria, in resistance to glycopeptides, particularly to vancomycine, said resistance being of the type inducible by the vancomycine and non-inducible by teicoplanine. The invention also relates to the utilisation of fragments of nucleotides of the gene van B for the detection of resistances to glycopeptides.
    Type: Grant
    Filed: April 14, 1999
    Date of Patent: May 27, 2003
    Assignee: Institut Pasteur
    Inventors: Michel Arthur, Sylvie Dutka-Malen, Stefan Evers, Patrice Courvalin
  • Nucleic acids conferring and inducible resistance to glycopeptides particularly in gram-positive bacteria
    Patent number: 6087106
    Abstract: The invention relates to a protein VanB involved, in Gram-positive bacteria, in resistance to glycopeptides, particularly to vancomycine, said resistance being of the type inducible by the vancomycine and non-inducible by teicoplanine. The invention also relates to the utilisation of fragments of nucleotides of the gene van B for the detection of resistances to glycopeptides.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: July 11, 2000
    Assignee: Institut Pasteur
    Inventors: Michel Arthur, Sylvie Dutka-Malen, Stefan Evers, Patrice Courvalin
  • Polynucleotides and their use for detecting enterococci and streptococci bacterial strains
    Patent number: 6054269
    Abstract: Polynucleotides and oligonucleotides for identification of species of the Streptococcus genus and the Enterococcus genus are provided. The polynucleotides and oligonucleotides are useful as probes and primers. Polypeptides expressed by the polynucleotides and oligonucleotides are useful for the preparation of monoclonal and polyclonal antibodies that recognize the polypeptides.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: April 25, 2000
    Assignee: Institut Pasteur
    Inventors: Fabien Garnier, Guy Gerbaud, Marc Galimand, Patrice Courvalin, Sylvie Dukta-Malen, Murielle Charles, Stefan Evers, Barbara Casadewall
  • Polypeptides implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria, nucleotide sequence coding for these polypeptides and use for diagnosis
    Patent number: 6013508
    Abstract: The invention relates to compositions and nucleic acids encoding polypeptides involved in the expression of resistance to glycopeptides, in particular to vancomycin and/or teicoplanin. The invention also relates to vectors containing said nucleic acids, transformed host cells and their use for the diagnosis of resistance to glycopeptides.
    Type: Grant
    Filed: November 28, 1997
    Date of Patent: January 11, 2000
    Assignee: Institut Pasteur
    Inventors: Michel Arthur, Sylvie Dukta-Malen, Catherine Molinas, Patrice Courvalin
  • Probes for the detection of nucleotide sequences implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria
    Patent number: 5871910
    Abstract: The invention relates to isolated polynucleotides and probes which are optionally labelled and which hybridize with polynucleotides encoding polypeptides implicated in the bacterial resistance to vancomycin, teicoplanin and to both vancomycin and teicoplanin. The invention also relates to the utilization of these polynucleotide probes for the diagnosis of resistance to the glycopeptides.
    Type: Grant
    Filed: August 5, 1994
    Date of Patent: February 16, 1999
    Assignee: Institut Pasteur
    Inventors: Michel Arthur, Sylvie Dukta-Malen, Catherine Molinas, Patrice Courvalin
  • Protein conferring an inducible resistance to glycopeptides, particularly in gram-positive bacteria
    Patent number: 5770361
    Abstract: The invention relates to a protein VanB involved, in Gram-positive bacteria, in resistance to glycopeptides, particularly to vancomycine, said resistance being of the type inducible by the vancomycine and non-inducible by teicoplanine. The invention also relates to the utilisation of fragments of nucleotides of the gene van B for the detection of resistances to glycopeptides.
    Type: Grant
    Filed: September 7, 1995
    Date of Patent: June 23, 1998
    Assignee: Institut Pasteur
    Inventors: Michel Arthur, Sylvie Dutka-Malen, Stefan Evers, Patrice Courvalin