Patents by Inventor Patrice Talaga

Patrice Talaga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8034958
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: October 11, 2011
    Assignee: UOB Pharma, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • Compounds comprising an oxazoline or thiazoline moiety, processes for making them, and their uses
    Patent number: 7863450
    Abstract: The present invention relates to compounds comprising an oxazoline or thiazoline moiety, processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H3-receptor ligands, (I), wherein A1 is CH C(CH3) or N; R1 is hydrogen or halogen; R2 is (II); A2 is O or S; R3 is hydrogen, halogen, C1-4 alkyl or C1-4 alkoxy; R4 is hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, trifluoromethyl or —O—(CH2)n-NR12aR each CH2 in —O—(CH2)n-NR12aR12b being optionally substituted by one or two C1-4 alkyl; R5 is hydrogen or —O—(CH2)m—NR13aR13b, each CH2 in —O—(CH2)m—NR13aR13b being optionally substituted by one or two C1-4 alkyl, and at least one of R4 and R5 should be a —O—(CH2)n-NR12/13aR12/13b group.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: January 4, 2011
    Assignee: UCB Pharma, S.A.
    Inventors: Sylvain Celanire, Patrice Talaga, Regorius Leurs, Frederic Denonne, Henkdrik Timmerman, Florence Lebon
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20100222576
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: February 17, 2010
    Publication date: September 2, 2010
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 7692028
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: April 6, 2010
    Assignee: UCB Pharma, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • Chemical compounds with dual activity, processes for their preparation and pharmaceutical compositions
    Patent number: 7544675
    Abstract: The present invention concerns chemical compounds combining affinity and antagonism against the human m3 muscarinic receptor with activity as selective phosphodiesterase IV (PDE IV) inhibitors, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: March 29, 2003
    Date of Patent: June 9, 2009
    Assignee: UCB, S.A.
    Inventors: Laurent Provins, Berend Jan Van Keulen, John Surtees, Patrice Talaga, Bernard Christophe
  • Compounds Comprising an Oxazoline or Thiazoline Moiety, Processes for Making Them, and Their Uses
    Publication number: 20080161331
    Abstract: The present invention relates to compounds comprising an oxazoline or thiazoline moiety, processes for preparing them, pharmaceutical compositions comprising said compounds and their uses as H3-receptor ligands, (I), wherein A1 is CH C(CH3) or N; R1 is hydrogen or halogen; R2 is (II); A2 is O or S; R3 is hydrogen, halogen, C1-4 alkyl or C1-4 alkoxy; R4 is hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, trifluoromethyl or —O—(CH2)n-NR12aR each CH2 in —O—(CH2)n-NR12aR 12b being optionally substituted by one or two C1-4 alkyl; R5 is hydrogen or —O—(CH2)m—NR13aR13b, each CH2 in —O—(CH2)m—NR13aR13b being optionally substituted by one or two C1-4 alkyl, and at least one of R4 and R5 should be a —O—(CH2)n-NR12/13aR12/13b group.
    Type: Application
    Filed: March 29, 2006
    Publication date: July 3, 2008
    Applicant: UCB PHARMA, S.A.
    Inventors: Regorius Leurs, Henkdrik Timmerman, Sylvain Celanire, Patrice Talaga, Frederic Denonne, Florence Lebon
  • Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors
    Patent number: 7361668
    Abstract: The invention concerns quinuclidine derivatives of formula I or II wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention show high affinities for m3 and/or m2 muscarinic receptors and are particularly suited for treating urinary incontinence.
    Type: Grant
    Filed: September 23, 2002
    Date of Patent: April 22, 2008
    Assignee: UCB, S.A.
    Inventors: Michel Guyaux, Chimmanamada U. Dinesh, Charles Mioskowski, Luc Quere, Jean-Philippe Starck, Patrice Talaga, Alain Wagner, Matteo Zanda
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 7358276
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: April 15, 2008
    Assignee: UCB, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • Chemical compounds with dual activity, processes for their preparation and pharmaceutical compositions
    Publication number: 20060074068
    Abstract: The present invention concerns chemical compounds combining affinity and antagonism against the human m3 muscarinic receptor with activity as selective phosphodiesterase IV (PDE IV) inhibitors, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: March 29, 2003
    Publication date: April 6, 2006
    Applicant: UCB, S.A.
    Inventors: Laurent Provins, Berend Van Keulen, John Surtees, Patrice Talaga, Bernard Christophe
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20050171188
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 4, 2005
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20050171187
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 4, 2005
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 6911461
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: June 28, 2005
    Assignee: UCB, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • Quinuclidine derivatives processes for preparing them and their uses as m2 and/or m3 muscarinic receptor inhibitors
    Publication number: 20050020660
    Abstract: The invention concerns quinuclidine derivatives of formula I or II wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention_show high affinities for m3 and/or m2 muscarinic receptors and are particularly suited for treating urinary incontinence.
    Type: Application
    Filed: September 23, 2002
    Publication date: January 27, 2005
    Inventors: Michel Guyaux, Chimmanamada Dinesh, Charles Mioskowski, Luc Quere, Jean-Philippe Starck, Patrice Talaga, Alain Wagner, Mateo Zanda
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 6806287
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: October 19, 2004
    Assignee: UCB, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 6784197
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula (I) wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: August 31, 2004
    Assignee: UCB S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20040116507
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, 1
    Type: Application
    Filed: October 28, 2003
    Publication date: June 17, 2004
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20040087646
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, 1
    Type: Application
    Filed: October 28, 2003
    Publication date: May 6, 2004
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20030120080
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula (I) wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: August 20, 2002
    Publication date: June 26, 2003
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • Alkylation of azaglycine derivatives
    Patent number: 5326875
    Abstract: A process for the preparation of alkylated azaglycine derivatives of the formula IX--(A).sub.n --N(R)--NH--CO--NH.sub.2, (I)is described in which X is an amino protective group, C.sub.1 -C.sub.8 -alkanoyl, C.sub.6 -C.sub.14 -arylcarbonyl or C.sub.6 -C.sub.14 -aryl-C.sub.1 -C.sub.4 -alkanoyl, A is amino acid or imino acid radicals optionally protected on the third function, n is 0-10, X being C.sub.1 -C.sub.8 -alkanoyl, C.sub.6 -C.sub.14 -arylcarbonyl or C.sub.6 -C.sub.14 -aryl-C.sub.1 -C.sub.4 -alkanoyl if n=0, and R is C.sub.1 -C.sub.8 -alkyl, C.sub.6 -C.sub.14 -aryl-C.sub.1 -C.sub.4 -alkanoyl or C.sub.5 -C.sub.12 -heteroaryl-C.sub.1 -C.sub.4 -alkanoyl, which comprises reacting a compound of the formula X--(A).sub.n --NH--NH--CO--NH.sub.2, in which X, A and n have the abovementioned meanings, with a primary or secondary alcohol and excess DEAD, and a tri-C.sub.1 -C.sub.6 -alkylphosphine, tri-C.sub.6 -C.sub.14 -arylphosphine or pyridyl-di-C.sub.6 -C.sub.
    Type: Grant
    Filed: January 21, 1992
    Date of Patent: July 5, 1994
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Patrice Talaga, Wolfgang Konig