Patents by Inventor Patricia Bourne

Patricia Bourne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies that bind to human programmed death ligand 1 (PD-L1)
    Patent number: 9709568
    Abstract: The present disclosure provides isolated antibodies that specifically bind to human PD-L1, as well as antigen binding fragments of such antibodies, and kits comprising the anti-PD-L1 antibodies or binding fragments and a set of reagents for detecting a complex of the antibody, or antigen binding fragment thereof, bound to human PD-L1. The antibodies and antigen binding fragments of this disclosure are useful for immunohistochemical detection of human PD-L1 expression in tissue samples. Nucleic acid molecules encoding the antibodies and antigen binding fragments of this disclosure, as well as expression vectors and host cells for expression thereof, are also provided.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: July 18, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Robert H. Pierce, Patricia Bourne, Linda Liang, Michael Bigler
  • ANTIBODIES THAT BIND TO HUMAN PROGRAMMED DEATH LIGAND 1 (PD-L1)
    Publication number: 20150355184
    Abstract: The present disclosure provides isolated antibodies that specifically bind to human PD-L1, as well as antigen binding fragments of such antibodies, and kits comprising the anti-PD-L1 antibodies or binding fragments and a set of reagents for detecting a complex of the antibody, or antigen binding fragment thereof, bound to human PD-L1. The antibodies and antigen binding fragments of this disclosure are useful for immunohistochemical detection of human PD-L1 expression in tissue samples. Nucleic acid molecules encoding the antibodies and antigen binding fragments of this disclosure, as well as expression vectors and host cells for expression thereof, are also provided.
    Type: Application
    Filed: December 18, 2013
    Publication date: December 10, 2015
    Inventors: Robert H. Pierce, Patricia Bourne, Linda Liang, Michael Bigler