Patents by Inventor Patricia Contreras

Patricia Contreras has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metaphit and related compounds as acylating agents for the (3H)phencyclidine receptors
    Patent number: 4762846
    Abstract: A derivative of phencyclidine (1) bearing an isothiocyanate moiety on the meta position of the aromatic ring (3; Metaphit as methanesulfonate and HCl salt) has been synthesized and identified as a rapid and specific site-directed acylating agent of the [.sup.3 H]-phencyclidine binding site in rat brain homogenates. Additional related compounds to Metaphit are Thiophit (oxalate salt), Ethylphit (HCl salt), and Isopropylphit (HCl salt).
    Type: Grant
    Filed: January 31, 1986
    Date of Patent: August 9, 1988
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Kenner C. Rice, Michael F. Rafferty, Arthur E. Jacobson, Patricia Contreras, Thomas L. O'Donohue, Ralph A. Lessor, Mariena V. Mattson
  • Metaphit, a specific acylating agent for the [.sup.3 H] phencyclidine
    Patent number: 4598153
    Abstract: A derivative of phencyclidine (1) bearing an isothiocyanate moiety of the meta position of the aromatic ring (2; Metaphit) has been synthesized and identified as a rapid and specific site-directed acylating agent of the [.sup.3 H]-phencyclidine binding site in rat brain homogenates.
    Type: Grant
    Filed: December 19, 1984
    Date of Patent: July 1, 1986
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Kenner C. Rice, Michael F. Rafferty, Arthur E. Jacobson, Patricia Contreras, Thomas L. O'Donohue, Ralph A. Lessor, Mariena V. Mattson