Patents by Inventor Patricia Pelton

Patricia Pelton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzoazepin-oxy-acetic acid derivatives as PPAR-delta agonists used for the increase of HDL-C, lower LDL-C and lower cholesterol
    Patent number: 8633184
    Abstract: The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia, stroke, irritable bowel disorder, inflammation, cataract, cardiovascular diseases, Metabolic X Syndrome, hyper-LDL-cholesterolemia, dyslipidemia (including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia, and hypo-HDL-cholesterolemia), atherosclerosis, obesity, and other disorders related to lipid metabolism and energy homeostasis complications thereof, using compounds of the invention are also described.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: January 21, 2014
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Gee-Hong Kuo, Yan Zhang, Lan Shen, Songfeng Lu, Keith T. Demarest, Patricia Pelton
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 8242173
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: August 14, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Alan DeAngelis, Keith T Demarest, Gee-Hong Kuo, Patricia Pelton, Aihua Wang, Rui Zhang
  • 3,4-dihydro-2H-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors
    Patent number: 8012963
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: September 6, 2011
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Gee-Hong Kuo, Thomas Rano, Aihua Wang, Catherine Prouty, Keith T. Demarest, Patricia Pelton
  • 1,2,3,4-tetrahydro-quinoline derivatives as CETP inhibitors
    Patent number: 7928238
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: April 19, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Thomas Rano, Gee-Hong Kuo, Ellen Sieber-McMaster, Keith T. Demarest, Patricia Pelton, Aihua Wang
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7875744
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: January 25, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
    Publication number: 20100331406
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: September 1, 2010
    Publication date: December 30, 2010
    Inventors: Alan DEANGELIS, Keith T. Demarest, Gee-Hong Kuo, Patricia Pelton, Aihua Wang, Rui Zhang
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7812053
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: October 12, 2010
    Assignee: Janssen Pharmaceuticals NV
    Inventors: Alan DeAngelis, Keith T. Demarest, Gee-Hong Kuo, Patricia Pelton, Aihua Wang, Rui Zhang
  • 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS
    Publication number: 20100227857
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Application
    Filed: May 18, 2010
    Publication date: September 9, 2010
    Inventors: Gee-Hong Kuo, Thomas Rano, Aihua Wang, Catherine Prouty, Keith T. Demarest, Patricia Pelton
  • 3,4-dihydro-2h-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors
    Patent number: 7749995
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: July 6, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Gee-Hong Kuo, Aihua Wang, Thomas Rano, Catherine Prouty, Keith T. Demarest, Patricia Pelton
  • BENZOAZEPIN-OXY-ACETIC ACID DERIVATIVES AS PPAR-DELTA AGONISTS USED FOR THE INCREASE OF HDL-C, LOWER LDL-C AND LOWER CHOLESTEROL
    Publication number: 20100120748
    Abstract: The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia, stroke, irritable bowel disorder, inflammation, cataract, cardiovascular diseases, Metabolic X Syndrome, hyper-LDL-cholesterolemia, dyslipidemia (including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia, and hypo-HDL-cholesterolemia), atherosclerosis, obesity, and other disorders related to lipid metabolism and energy homeostasis complications thereof, using compounds of the invention are also described.
    Type: Application
    Filed: January 19, 2010
    Publication date: May 13, 2010
    Inventors: Gee-Hong Kuo, Yan Zhang, Lan Shen, Songfeng Lu, Keith T. Demarest, Patricia Pelton
  • Benzoazepin-oxy-acetic acid derivatives as PPAR-delta agonists used for the increase of HDL-C, lower LDL-C and lower cholesterol
    Patent number: 7678786
    Abstract: The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia, stroke, irritable bowel disorder, inflammation, cataract, cardiovascular diseases, Metabolic X Syndrome, hyper-LDL-cholesterolemia, dyslipidemia (including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia, and hypo-HDL-cholesterolemia), atherosclerosis, obesity, and other disorders related to lipid metabolism and energy homeostasis complications thereof, using compounds of the invention are also described.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: March 16, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Gee-Hong Kuo, Yan Zhang, Lan Shen, Songfeng Lu, Keith T. Demarest, Patricia Pelton
  • 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
    Publication number: 20090318332
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: August 28, 2009
    Publication date: December 24, 2009
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7598416
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: June 23, 2008
    Date of Patent: October 6, 2009
    Assignee: Janssen Pharmaceutica N. V.
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
    Publication number: 20080269336
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: June 23, 2008
    Publication date: October 30, 2008
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7425649
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: September 16, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS
    Publication number: 20070265304
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Application
    Filed: May 10, 2007
    Publication date: November 15, 2007
    Inventors: Thomas Rano, Gee-Hong Kuo, Ellen Sieber-McMaster, Keith T. Demarest, Patricia Pelton, Aihua Wang
  • 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS
    Publication number: 20070265252
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Application
    Filed: May 10, 2007
    Publication date: November 15, 2007
    Inventors: Gee-Hong Kuo, Aihua Wang, Thomas Rano, Catherine Prouty, Keith T. Demarest, Patricia Pelton
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Publication number: 20060058382
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: September 14, 2005
    Publication date: March 16, 2006
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Publication number: 20060058393
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: September 14, 2005
    Publication date: March 16, 2006
    Inventors: Alan DeAngelis, Keith Demarest, Gee-Hong Kuo, Patricia Pelton, Aihua Wang, Rui Zhang