Patents by Inventor Patricio Manuel Viera Araujo Soares Da Silva

Patricio Manuel Viera Araujo Soares Da Silva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of 5H-dibenz/b,f/azepine-5-carboxamide derivatives for treating fibromyalgia
    Patent number: 9855277
    Abstract: The use of 5H-dibenz/b,f/azepine-5-carboxamide derivatives for treating fibromyalgia. Useful 5H-dibenz/b,f/azepine-5-carboxamide derivatives include compounds of the formula (I): where R1 is hydrogen, alkyl, halogenalkyl, aralkyl, cycloalkyl, cycloalkylalkyl, alkoxy, aryl, or pyridyl; the term alkyl means a straight or branched hydrocarbon chain containing from 1 to 18 carbon atoms; the term halogen means fluorine, chlorine, bromine or iodine; the term cycloalkyl means an alicyclic saturated group with 3 to 6 carbon atoms; and the term aryl means an unsubstituted phenyl group or phenyl substituted by alkoxy, halogen or nitro group.
    Type: Grant
    Filed: July 27, 2009
    Date of Patent: January 2, 2018
    Assignee: BIAL—PORTELA & CA, S.A.
    Inventor: Patricio Manuel Viera Araújo Soares Da Silva
  • Peripherally-selective inhibitors of dopamine-?-hydroxylase and method of their preparation
    Patent number: 7259271
    Abstract: Compounds of formula I: where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkylaryl, alkyloxy, hydroxy, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; R4 signifies hydrogen, alkyl or alkylaryl group; X is CH2, O or S, and n is 1, 2 or 3, with the proviso that if X is CH2, n is not 1, and a method for their preparation. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: August 21, 2007
    Assignee: Portela & C.A., S.A.
    Inventors: David Alexander Learmonth, Patricio Manuel Viera Araújo Soares da Silva, Alexander Beliaev
  • Peripherally-Selective Inhibitors of Dopamine-ß-Hydroxylase And Method Of Their Preparation
    Publication number: 20070015730
    Abstract: Compounds of formula I: where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkylaryl, alkyloxy, hydroxy, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; R4 signifies hydrogen, alkyl or alkylaryl group; X is CH2, O or S, and n is 1, 2 or 3, with the proviso that if X is CH2, n is not 1, and a method for their preparation. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.
    Type: Application
    Filed: September 20, 2006
    Publication date: January 18, 2007
    Applicant: PORTELA & C.A., S.A.
    Inventors: David Learmonth, Patricio Manuel Viera Araujo Soares da Silva, Alexander Beliaev
  • Peripherally-selective inhibitors of dopamine-?-hydroxylase and method of their preparation
    Patent number: 7125904
    Abstract: Compounds of formula I: where R1, R2 and R3 are the same or different and signify hydrogens, halogens, alkyl, alkylaryl, alkyloxy, hydroxy, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; R4 signifies hydrogen, alkyl or alkylaryl group; X is CH2, O or S, and n is 1, 2 or 3, with the proviso that if X is CH2, n is not 1, and a method for their preparation. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.
    Type: Grant
    Filed: October 8, 2003
    Date of Patent: October 24, 2006
    Assignee: Portela & C.A., S.A.
    Inventors: David Alexander Learmonth, Patricio Manuel Viera Araújo Soares da Silva, Alexander Beliaev
  • Peripherally-selective inhibitors of dopamine-beta-hydroxylase and method of their preparation
    Publication number: 20040142996
    Abstract: Compounds of formula I: t,0010
    Type: Application
    Filed: October 8, 2003
    Publication date: July 22, 2004
    Applicant: Portela & C.A., S.A.
    Inventors: David Alexander Learmonth, Patricio Manuel Viera Araujo Soares da Silva, Alexander Beliaev
  • Substituted 2-phenyl-1-(3,4-dihydroxy-5-nitrophenyl)-1-ethanones, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them
    Patent number: 6512136
    Abstract: New compounds of formula I are described The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders, where a reduction in the O-methylation of catecholamines may be of therapeutical benefit, such as Parkinson's disease and parkinsonian disorders, gastrointestinal disturbances, edema formation states and hypertension.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: January 28, 2003
    Assignee: Portela & C.A., S.A.
    Inventors: Jan Benes, Patricio Manuel Viera Araujo Soares Da Silva, David Alexander Learmonth