Abstract: Aspects of this disclosure relate generally to the use of biomaterials for the in vivo generation of CAR expressing cells. In some embodiments, the biomaterials comprise one or more of a cell recruitment composition, a viral vector, and/or a cell activation agent.

Abstract: Methods, systems, and apparatus for provisioning a network device are disclosed. In one aspect, a message is received by a translation device from a controller. A determination is made, by the translation device, that the received message includes data that is destined for multiple different downstream network devices. A determination is made that a first downstream network device among the multiple different downstream network devices is incapable of being provisioned using a communications protocol of the received message. Data from the received message, that is destined for the first downstream network device, is translated, by the translation device, from the communications protocol of the received message to a translated message defined in a different protocol that is required to provision the first downstream network device. The translated message is transmitted, by the translation device, to the first downstream network device according to the different protocol.

Abstract: Methods, systems, and apparatus for provisioning a network device are disclosed. In one aspect, a message is received by a translation device from a controller. A determination is made, by the translation device, that the received message includes data that is destined for multiple different downstream network devices. A determination is made that a first downstream network device among the multiple different downstream network devices is incapable of being provisioned using a communications protocol of the received message. Data from the received message, that is destined for the first downstream network device, is translated, by the translation device, from the communications protocol of the received message to a translated message defined in a different protocol that is required to provision the first downstream network device. The translated message is transmitted, by the translation device, to the first downstream network device according to the different protocol.

Abstract: Methods, systems, and apparatus for providing content in a multicast stream are disclosed. In one aspect, analytical information of a plurality of individual data sessions between user devices and a content server is received. The analytical information of each of the plurality of individual data sessions is based on a packet inspection analysis of data transmitted in the respective individual data sessions. A same set of content being delivered to at least a portion of the user devices based on the analytical information is determined. In response to the determination, a multicast stream condition is determined to be met based on at least one performance metric of a network over which the same set of content is being delivered. In response to determining that the multicast stream condition has been met, a multicast stream that provides the content in a looping stream is initiated.

Abstract: Methods, systems, and apparatus for providing content in a multicast stream are disclosed. In one aspect, analytical information of a plurality of individual data sessions between user devices and a content server is received. The analytical information of each of the plurality of individual data sessions is based on a packet inspection analysis of data transmitted in the respective individual data sessions. A same set of content being delivered to at least a portion of the user devices based on the analytical information is determined. In response to the determination, a multicast stream condition is determined to be met based on at least one performance metric of a network over which the same set of content is being delivered. In response to determining that the multicast stream condition has been met, a multicast stream that provides the content in a looping stream is initiated.