Patents by Inventor Patrick Ahl

Patrick Ahl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cochleate compositions directed against expression of proteins
    Patent number: 9259392
    Abstract: Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: February 16, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Susan Gould-Fogerite, Raphael J. Mannino, Patrick Ahl, Gaofeng Shang, Zi Wei Chen, Sara L. Krause-Elsmore
  • COCHLEATE COMPOSITIONS DIRECTED AGAINST EXPRESSION OF PROTEINS
    Publication number: 20140186430
    Abstract: Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.
    Type: Application
    Filed: September 27, 2013
    Publication date: July 3, 2014
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Susan Gould-Fogerite, Raphael J. Mannino, Patrick Ahl, Gaofeng Shang, Zi Wei Chen, Sara L. Krause-Elsmore
  • Cochleate compositions directed against expression of proteins
    Patent number: 8546555
    Abstract: Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: October 1, 2013
    Assignee: Biodelivery Sciences International, Inc.
    Inventors: Susan Gould-Fogerite, Raphael J. Mannino, Patrick Ahl, Gaofeng Shang, Zi Wei Chen, Sara L. Krause-Elsmore
  • COCHLEATE COMPOSITIONS DIRECTED AGAINST EXPRESSION OF PROTEINS
    Publication number: 20120282322
    Abstract: Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.
    Type: Application
    Filed: November 17, 2011
    Publication date: November 8, 2012
    Applicant: BIODELIVERY SCIENCES INTERNATIONAL, INC.
    Inventors: Susan Gould-Fogerite, Raphael J. Mannino, Patrick Ahl, Gaofeng Shang, Zi Wei Chen, Sara L. Krause-Elsmore
  • Cochleate compositions directed against expression of proteins
    Publication number: 20110091523
    Abstract: Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.
    Type: Application
    Filed: February 11, 2010
    Publication date: April 21, 2011
    Applicant: BioDelivery Sciences International, Inc.
    Inventors: Susan Gould-Fogerite, Raphael J. Mannino, Patrick Ahl, Gaofeng Shang, Zi Wei Chen, Sara L. Krause-Elsmore
  • Encapsulation of Bioactive Complexes in Liposomes
    Publication number: 20090068256
    Abstract: This invention provides a method to prepare liposome-encapsulated bioactive agents, such as nucleic acids, comprising complexation of the bioactive agents to reverse micelles prior to forming liposomes, as well as methods of using the liposomes so formed and formulations to deliver nucleic acids to cells.
    Type: Application
    Filed: August 25, 2008
    Publication date: March 12, 2009
    Inventors: Paul Meers, Tong Shangguan, Donna Cabral-Lilly, Andrew Janoff, Patrick Ahl
  • Encapsulation of bioactive complexes in liposomes
    Patent number: 7491409
    Abstract: This invention provides a method to prepare liposome-encapsulated bioactive agents such as nucleic acids, comprising complexation of the bioactive agents in reverse micelles prior to forming liposomes, as well as methods of using the liposomes so formed and formulations to deliver nucleic acids to cells.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: February 17, 2009
    Assignee: Transave, Inc.
    Inventors: Paul R. Meers, Tong Shangguan, Donna Cabral-Lilly, Patrick Ahl, Andrew S. Janoff
  • Cochleate compositions directed against expression of proteins
    Publication number: 20080009457
    Abstract: Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.
    Type: Application
    Filed: January 11, 2007
    Publication date: January 10, 2008
    Applicant: BioDelivery Sciences International, Inc.
    Inventors: Susan Gould-Fogerite, Raphael Mannino, Patrick Ahl, Gaofeng Shang, Zi Chen, Sara Krause-Elsmore
  • Modular targeted liposomal delivery system
    Publication number: 20060172003
    Abstract: A liposome including a fusogenic liposome, a linking moiety and a targeting moiety. The fusogenic liposome is a lipid bilayer encapsulating contents. The linking moiety is electrostatically bound to the lipid bilayer, and the targeting moiety is covalently bound to the linking moiety. The liposome may also include a stabilizing moiety interposed between the linking and targeting moieties, and covalently bound to both. Alternatively, the stabilizing and targeting moieties may be covalently bound to separate linking moieties, the linking moieties being electrostatically bound to the lipid bilayer.
    Type: Application
    Filed: February 22, 2006
    Publication date: August 3, 2006
    Applicant: Transave, Inc.
    Inventors: Paul Meers, Tong Shangguan, Donna Cabral-Lilly, Patrick Ahl, Ravi Erukulla, Andrew Janoff
  • Modular targeted liposomal delivery system
    Patent number: 7060291
    Abstract: A liposome including a fusogenic liposome, a linking moiety and a targeting moiety. The fusogenic liposome is a lipid bilayer encapsulating contents. The linking moiety is electrostatically bound to the lipid bilayer, and the targeting moiety is covalently bound to the linking moiety. The liposome may also include a stabilizing moiety interposed between the linking and targeting moieties, and covalently bound to both. Alternatively, the stabilizing and targeting moieties may be covalently bound to separate linking moieties, the linking moieties being electrostatically bound to the lipid bilayer.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: June 13, 2006
    Assignee: Transave, Inc.
    Inventors: Paul R. Meers, Tong Shangguan, Donna Cabral-Lilly, Patrick Ahl, Ravi Erukulla, Andrew Janoff
  • Cochleate compositions directed against expression of proteins
    Publication number: 20050013855
    Abstract: Disclosed herein are novel siRNA-cochleate and morpholino-cochleate compositions. Also disclosed are methods of making and using siRNA-cochleate and morpholino-cochleate compositions.
    Type: Application
    Filed: April 9, 2004
    Publication date: January 20, 2005
    Applicants: BioDelivery Sciences International, Inc., University of Medicine and Dentistry of New Jersey
    Inventors: Susan Gould-Fogerite, Raphael Mannino, Patrick Ahl, Gaofeng Shang, Zi Chen, Sara Krause-Elsmore