Patents by Inventor Patrick Bolan
Patrick Bolan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11241296Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: November 30, 2017Date of Patent: February 8, 2022Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 11009577Abstract: A system and computerized method for generating magnetic resonance imaging (MRI) images is provided that includes accessing data acquired from a subject using an MRI system that includes Nyquist ghosts and processing the data using a cost function that exploits a cosine and sine modulation in a ghosted image component of the data. An image of the subject is produced from the data after processing the data using the cost function.Type: GrantFiled: June 3, 2019Date of Patent: May 18, 2021Assignee: Regents of the University of MinnesotaInventors: Jessica McKay, Patrick Bolan
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Publication number: 20190369192Abstract: A system and computerized method for generating magnetic resonance imaging (MRI) images is provided that includes accessing data acquired from a subject using an MRI system that includes Nyquist ghosts and processing the data using a cost function that exploits a cosine and sine modulation in a ghosted image component of the data. An image of the subject is produced from the data after processing the data using the cost function.Type: ApplicationFiled: June 3, 2019Publication date: December 5, 2019Inventors: Jessica McKay, Patrick Bolan
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Publication number: 20180085184Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: November 30, 2017Publication date: March 29, 2018Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 9861450Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: December 11, 2015Date of Patent: January 9, 2018Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 9795455Abstract: A radiographic marker containing a sensing medium that initially includes a gas and liquid mixture for producing increased signal intensity in a first imaging modality. The radiographic marker can have a permeable portion allowing the exchange of the gases or liquids of the sensing medium to be changed or exchanged for at least a second fluid in the surrounding tissue to reduce the bubbles or air pockets created by the gas portion of the sensing medium. The change or exchange of gas for the second liquid in the radiographic marker produces a detectable signal intensity of the radiographic marker in a second imaging modality different from the first imaging modality.Type: GrantFiled: August 22, 2014Date of Patent: October 24, 2017Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Mark C. Gross, Daniel A. Halpern, Michael T. Nelson
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Publication number: 20160100910Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: December 11, 2015Publication date: April 14, 2016Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Publication number: 20160051337Abstract: A radiographic marker containing a sensing medium that initially includes a gas and liquid mixture for producing increased signal intensity in a first imaging modality. The radiographic marker can have a permeable portion allowing the exchange of the gases or liquids of the sensing medium to be changed or exchanged for at least a second fluid in the surrounding tissue to reduce the bubbles or air pockets created by the gas portion of the sensing medium. The change or exchange of gas for the second liquid in the radiographic marker produces a detectable signal intensity of the radiographic marker in a second imaging modality different from the first imaging modality.Type: ApplicationFiled: August 22, 2014Publication date: February 25, 2016Inventors: Patrick Bolan, Mark C. Gross, Daniel A. Halpern, Michael T. Nelson
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Patent number: 9241773Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: March 2, 2015Date of Patent: January 26, 2016Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Publication number: 20150173848Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: March 2, 2015Publication date: June 25, 2015Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 8966735Abstract: An implantable tissue marker incorporates a contrast agent scaled within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: September 10, 2013Date of Patent: March 3, 2015Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Publication number: 20140187911Abstract: An implantable tissue marker incorporates a contrast agent scaled within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: September 10, 2013Publication date: July 3, 2014Applicant: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Patent number: 8544162Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: GrantFiled: April 19, 2010Date of Patent: October 1, 2013Assignee: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Publication number: 20100287887Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: April 19, 2010Publication date: November 18, 2010Applicant: Breast-Med, Inc.Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
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Publication number: 20070110665Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.Type: ApplicationFiled: November 17, 2005Publication date: May 17, 2007Inventors: Patrick Bolan, Michael Garwood, Michael Nelson, Daniel Halpern
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Patent number: 6650116Abstract: A method and system for performing MRI and NMR spectroscopy that improves the dynamic range of the received signal by using adiabatic RF pulses for spin excitation rather than for spin inversion. The preferred adiabatic RF excitation produces a spatially varying phase across the slab, and a sharp slab profile. The phase variation is divided up by a phase-encoding gradient into voxels having a phase variation that is negligible over the width of the voxel. The phase variation in the slab-select direction is, on the whole, large enough that the peak amplitude of the received signal is reduced and the signal width broadened. This reduces the dynamic range required of the analog to digital converter used in a NMR system. A NMR system suitable for carrying out the methods of the invention is also disclosed.Type: GrantFiled: September 24, 2001Date of Patent: November 18, 2003Assignee: Regents of the University of MinnesotaInventors: Michael G. Garwood, Kamil Ugurbil, Lance DelaBarre, Patrick Bolan
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Publication number: 20020153889Abstract: A method and system for performing MRI and NMR spectroscopy that improves the dynamic range of the received signal by using adiabatic RF pulses for spin excitation rather than for spin inversion. The preferred adiabatic RF excitation produces a spatially varying phase across the slab, and a sharp slab profile. The phase variation is divided up by a phase-encoding gradient into voxels having a phase variation that is negligible over the width of the voxel. The phase variation in the slab-select direction is, on the whole, large enough that the peak amplitude of the received signal is reduced and the signal width broadened. This reduces the dynamic range required of the analog to digital converter used in a NMR system. A NMR system suitable for carrying out the methods of the invention is also disclosed.Type: ApplicationFiled: September 24, 2001Publication date: October 24, 2002Applicant: Regents of the University of MinnesotaInventors: Michael G. Garwood, Kamil Ugurbil, Lance DelaBarre, Patrick Bolan