Patents by Inventor Patrick Bolan

Patrick Bolan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11241296
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: February 8, 2022
    Assignee: Breast-Med, Inc.
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Patent number: 11009577
    Abstract: A system and computerized method for generating magnetic resonance imaging (MRI) images is provided that includes accessing data acquired from a subject using an MRI system that includes Nyquist ghosts and processing the data using a cost function that exploits a cosine and sine modulation in a ghosted image component of the data. An image of the subject is produced from the data after processing the data using the cost function.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: May 18, 2021
    Assignee: Regents of the University of Minnesota
    Inventors: Jessica McKay, Patrick Bolan
  • Publication number: 20190369192
    Abstract: A system and computerized method for generating magnetic resonance imaging (MRI) images is provided that includes accessing data acquired from a subject using an MRI system that includes Nyquist ghosts and processing the data using a cost function that exploits a cosine and sine modulation in a ghosted image component of the data. An image of the subject is produced from the data after processing the data using the cost function.
    Type: Application
    Filed: June 3, 2019
    Publication date: December 5, 2019
    Inventors: Jessica McKay, Patrick Bolan
  • Publication number: 20180085184
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Application
    Filed: November 30, 2017
    Publication date: March 29, 2018
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Patent number: 9861450
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: January 9, 2018
    Assignee: Breast-Med, Inc.
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Patent number: 9795455
    Abstract: A radiographic marker containing a sensing medium that initially includes a gas and liquid mixture for producing increased signal intensity in a first imaging modality. The radiographic marker can have a permeable portion allowing the exchange of the gases or liquids of the sensing medium to be changed or exchanged for at least a second fluid in the surrounding tissue to reduce the bubbles or air pockets created by the gas portion of the sensing medium. The change or exchange of gas for the second liquid in the radiographic marker produces a detectable signal intensity of the radiographic marker in a second imaging modality different from the first imaging modality.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: October 24, 2017
    Assignee: Breast-Med, Inc.
    Inventors: Patrick Bolan, Mark C. Gross, Daniel A. Halpern, Michael T. Nelson
  • Publication number: 20160100910
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Application
    Filed: December 11, 2015
    Publication date: April 14, 2016
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Publication number: 20160051337
    Abstract: A radiographic marker containing a sensing medium that initially includes a gas and liquid mixture for producing increased signal intensity in a first imaging modality. The radiographic marker can have a permeable portion allowing the exchange of the gases or liquids of the sensing medium to be changed or exchanged for at least a second fluid in the surrounding tissue to reduce the bubbles or air pockets created by the gas portion of the sensing medium. The change or exchange of gas for the second liquid in the radiographic marker produces a detectable signal intensity of the radiographic marker in a second imaging modality different from the first imaging modality.
    Type: Application
    Filed: August 22, 2014
    Publication date: February 25, 2016
    Inventors: Patrick Bolan, Mark C. Gross, Daniel A. Halpern, Michael T. Nelson
  • Patent number: 9241773
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: January 26, 2016
    Assignee: Breast-Med, Inc.
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Publication number: 20150173848
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Application
    Filed: March 2, 2015
    Publication date: June 25, 2015
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Patent number: 8966735
    Abstract: An implantable tissue marker incorporates a contrast agent scaled within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: March 3, 2015
    Assignee: Breast-Med, Inc.
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Publication number: 20140187911
    Abstract: An implantable tissue marker incorporates a contrast agent scaled within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Application
    Filed: September 10, 2013
    Publication date: July 3, 2014
    Applicant: Breast-Med, Inc.
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Patent number: 8544162
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: October 1, 2013
    Assignee: Breast-Med, Inc.
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Publication number: 20100287887
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Application
    Filed: April 19, 2010
    Publication date: November 18, 2010
    Applicant: Breast-Med, Inc.
    Inventors: Patrick Bolan, Michael G. Garwood, Michael T. Nelson, Daniel A. Halpern
  • Publication number: 20070110665
    Abstract: An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.
    Type: Application
    Filed: November 17, 2005
    Publication date: May 17, 2007
    Inventors: Patrick Bolan, Michael Garwood, Michael Nelson, Daniel Halpern
  • Patent number: 6650116
    Abstract: A method and system for performing MRI and NMR spectroscopy that improves the dynamic range of the received signal by using adiabatic RF pulses for spin excitation rather than for spin inversion. The preferred adiabatic RF excitation produces a spatially varying phase across the slab, and a sharp slab profile. The phase variation is divided up by a phase-encoding gradient into voxels having a phase variation that is negligible over the width of the voxel. The phase variation in the slab-select direction is, on the whole, large enough that the peak amplitude of the received signal is reduced and the signal width broadened. This reduces the dynamic range required of the analog to digital converter used in a NMR system. A NMR system suitable for carrying out the methods of the invention is also disclosed.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: November 18, 2003
    Assignee: Regents of the University of Minnesota
    Inventors: Michael G. Garwood, Kamil Ugurbil, Lance DelaBarre, Patrick Bolan
  • Publication number: 20020153889
    Abstract: A method and system for performing MRI and NMR spectroscopy that improves the dynamic range of the received signal by using adiabatic RF pulses for spin excitation rather than for spin inversion. The preferred adiabatic RF excitation produces a spatially varying phase across the slab, and a sharp slab profile. The phase variation is divided up by a phase-encoding gradient into voxels having a phase variation that is negligible over the width of the voxel. The phase variation in the slab-select direction is, on the whole, large enough that the peak amplitude of the received signal is reduced and the signal width broadened. This reduces the dynamic range required of the analog to digital converter used in a NMR system. A NMR system suitable for carrying out the methods of the invention is also disclosed.
    Type: Application
    Filed: September 24, 2001
    Publication date: October 24, 2002
    Applicant: Regents of the University of Minnesota
    Inventors: Michael G. Garwood, Kamil Ugurbil, Lance DelaBarre, Patrick Bolan