Patents by Inventor Patrick J. Casara

Patrick J. Casara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of inhibiting protozoal growth
    Patent number: 5196450
    Abstract: This invention relates to the use of .alpha.- halomethyl, .alpha.-acetylenic or .alpha.-allenic derivatives of arginine and agmatine, or their dehydro analogs, in the treatment of Chagas disease and Coccidiosis.
    Type: Grant
    Filed: September 30, 1991
    Date of Patent: March 23, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Albert Sjoerdsma, Peter P. McCann, Philippe Bey, Patrick J. Casara
  • .alpha.-Acetylenic derivatives of .alpha.-amino acids
    Patent number: 4260823
    Abstract: Novel acetylenic derivatives of .alpha.-amino acids of the following general structure: ##STR1## wherein R is hydrogen, alkylcarbonyl wherein the alkyl moiety has from 1 to 4 carbon atoms and is straight or branched, alkoxycarbonyl wherein the alkoxy moiety has from 1 to 4 carbon atoms and is straight or branched, or ##STR2## is hydrogen, a straight or branched lower alkyl group of 1 to 4 carbon atoms, benzyl or .rho.-hydroxybenzyl; each R.sub.1 is the same and is hydroxy, a straight or branched alkoxy group of from 1 to 8 carbon atoms, --NR.sub.3 R.sub.4 wherein each of R.sub.3 and R.sub.4 is hydrogen or a lower alkyl group of from 1 to 4 carbon atoms and can be the same or different, or ##STR3## wherein R.sub.5 is hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl or .rho.-hydroxybenzyl; and pharmaceutically acceptable salts and individual optical isomers thereof.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: April 7, 1981
    Assignee: Merrell Toruade et Compagnie
    Inventors: Patrick J. Casara, Michel Jung, Brian W. Metcalf
  • Lower alkyl 2-tri-(lower)alkylsilylacetylene-N-carbethoxyglycinates and process for using same
    Patent number: 4088667
    Abstract: Novel compounds of the formula ##STR1## wherein each of R and R.sub.1 is a lower alkyl group of from 1 to 4 carbon atoms, R.sub.3 is an alkyl group and a process employing said compounds.
    Type: Grant
    Filed: July 1, 1977
    Date of Patent: May 9, 1978
    Assignee: Merrell Toraude et Compagnie
    Inventors: Patrick J. Casara, Michel Jung, Brian Walter Metcalf