Abstract: The invention provides a natural killer (NK) cell engineered to express a chimeric antigen receptor (CAR), wherein the CAR comprises the extracellular domain of CD27 or a CD70-binding portion thereof, as well as compositions comprising the engineered NK cell, methods for producing the engineered NK cell, and therapeutic applications of the engineered NK cell, such as for treating neoplastic diseases.

Abstract: An example device includes a user interface component that implements a user interface and receives a visualization request value from user operations; an inspection database comprising an aggregation of inspection data; and a controller, comprising: a facility planning circuit that interprets a user facility visualization value in response to the visualization request value; a facility inspection data circuit that interprets the aggregation of inspection data in response to the user facility visualization value; a geographic depiction circuit that determines a geographic display boundary and a hierarchical inspection presentation for at least one industrial facility positioned within the geographic display boundary in response to the user facility visualization value and the aggregation of inspection data, and determines a user geographic display value in response to the geographic display boundary and the hierarchical inspection presentation.

Abstract: An apparatus for scanning and decoding barcodes includes an imager, a sample imaging area, and a processor. The imager is configured to capture images within a selectable field of view. The sample imaging area is configured to support a plurality of sample/tissue containers. Each sample/tissue container of the plurality of sample/tissue containers comprises a respective barcode. At least a portion of the plurality of sample/tissue containers are positioned within the field of view, such that a plurality of the respective barcodes is within the field of view. The processor is configured to receive captured images from the imager. The processor is configured to detect and decode each of the plurality of respective barcodes present in a first image of the captured images. The processor is also configured to define an associated region of interest for each barcode present in the first image.

Abstract: Compounds, such as compounds having Formula (I): wherein each variable is as described herein, that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.

Abstract: A steerable delivery system is provided for delivering a replacement heart valve to a native heart valve location. The steerable delivery system includes an outer sheath assembly having a capsule along a distal end portion for retaining the replacement heart valve in a compressed configuration. The capsule is constructed to provide both compression resistance and flexibility. The capsule may be formed with an outer polymer layer, a metal middle layer located on a radially inner surface of the outer polymer layer, and an inner liner located on a radially inner surface of the metal middle layer. A fluoroelastomer layer is provided for bonding the inner liner to the metal middle layer. The metal middle layer is preferably a metal hypotube.

Abstract: A lightweight ablator formulation has been developed which offers superior thermal performance compared to current state of the art ablator formulations. The lightweight ablator formulations described herein typically include at least one endothermically decomposing (energy absorbing) material with a fluxing agent resulting in significantly reduced backface temperature response and a more stable surface. According to one implementation the ablator composition comprises about 30 to about 70 percent by weight of a base silicone resin, about 25 to about 67 percent by weight of a low-density filler, about 3 to about 7 percent by weight of a curing agent and greater than 0 and up to about 10 percent by weight of a boron-containing compound.

Abstract: A lightweight ablator formulation has been developed which offers superior thermal performance compared to current state of the art ablator formulations. The lightweight ablator formulations described herein typically include at least one endothermically decomposing (energy absorbing) material with a fluxing agent resulting in significantly reduced backface temperature response and a more stable surface. According to one implementation the ablator composition comprises about 30 to about 70 percent by weight of a base silicone resin, about 25 to about 67 percent by weight of a low-density filler, about 3 to about 7 percent by weight of a curing agent and greater than 0 and up to about 10 percent by weight of a boron-containing compound.

Abstract: A lightweight ablator formulation has been developed which offers superior thermal performance compared to current state of the art ablator formulations. The lightweight ablator formulations described herein typically include at least one endothermically decomposing (energy absorbing) material with a fluxing agent resulting in significantly reduced backface temperature response and a more stable surface. According to one implementation the ablator composition comprises about 30 to about 70 percent by weight of a base silicone resin, about 25 to about 67 percent by weight of a low-density filler, about 3 to about 7 percent by weight of a curing agent and greater than 0 and up to about 10 percent by weight of a boron-containing compound.

Abstract: An antenna system for a wireless network that provides multi-band and/or multi-sector operation from a single location is provided. The antenna system may provide improved control and adjustment of antennas contained within a compact design to allow sectors of coverage provided by the antennas to be modified to accommodate different cell site parameters that may otherwise have been satisfied using a more distributed arrangement of antennas.

Abstract: A lightweight ablator formulation has been developed which offers superior thermal performance compared to current state of the art ablator formulations. The lightweight ablator formulations described herein typically include at least one endothermically decomposing (energy absorbing) material with a fluxing agent resulting in significantly reduced backface temperature response and a more stable surface. According to one implementation the ablator composition comprises about 30 to about 70 percent by weight of a base silicone resin, about 25 to about 67 percent by weight of a low-density filler, about 3 to about 7 percent by weight of a curing agent and greater than 0 and up to about 10 percent by weight of a boron-containing compound.

Abstract: The invention is directed to methods and systems for adjusting the vertical beam width of an imbalanced antenna. In one embodiment, first and second antenna arrays are imbalanced because one of the arrays has at least one more radiating element than the other. The additional gain created by additional radiating element(s) distorts the beam and alters the coverage area of the corresponding array, in embodiments. The tilt of the array having at least one more additional radiating element(s) is modified using phase shifting technology and based on the tilt of the array having fewer elements. By modifying tilt of the array having at least one more additional radiating element(s), the upper 3 dB points of the first and second array may be aligned to correct for the distorted beam and altered coverage area between the first and second arrays.

Abstract: A lightweight ablator formulation has been developed which offers superior thermal performance compared to current state of the art ablator formulations. The lightweight ablator formulations described herein typically include at least one endothermically decomposing (energy absorbing) material with a fluxing agent resulting in significantly reduced backface temperature response and a more stable surface. According to one implementation the ablator composition comprises about 30 to about 70 percent by weight of a base silicone resin, about 25 to about 67 percent by weight of a low-density filler, about 3 to about 7 percent by weight of a curing agent and greater than 0 and up to about 10 percent by weight of a boron-containing compound.

Abstract: A method of forming a thermal protection system for high speed aircraft is described. The method includes mechanically working an uncured ablator material into a first surface of a felt layer such that the ablator material penetrates a distance into a thickness of the felt layer thereby forming an region that has a mixture of felt and ablator material, adding additional uncured ablator material to the worked ablator material, and curing the combined ablator material.

Abstract: Detection and mitigation of signal conflict, such as a primary synchronization signal conflict, between broadcast cells in a wireless communication network is provided. Multiple broadcast cells may be provided in the network to provide sectors of coverage. A mobile communication device may operate within the network and attempt to attach to one or more of the broadcast cells. A synchronization signal conflict between neighboring broadcast cells may be identified and mitigated using one or more adjustments to the broadcast cells or signals emitted therefrom, which may allow for improved network performance, among other benefits.

Abstract: An antenna system for a wireless network that provides multi-band and/or multi-sector operation from a single location is provided. The antenna system may provide improved control and adjustment of antennas contained within a compact design to allow sectors of coverage provided by the antennas to be modified to accommodate different cell site parameters that may otherwise have been satisfied using a more distributed arrangement of antennas.

Abstract: Devices, systems, and methods for providing improved network performance in wireless communications networks using intelligent radiation selection are provided. A radio is communicatively coupled to an antenna and configured to provide a signal to the antenna for broadcast from a cell site. One or more input components are communicatively coupled to the radio to provide information on at least one of an internal or an external condition of the antenna, so that the radio can adjust or modify the signal provided to the antenna to change an emitted pattern of radiation from the antenna to reduce signal loss, or recover or help maintain an area of coverage provided by the antenna.

Abstract: The present invention provides tomatillo ideotypes and tomatillo plants with machine harvestable traits combined with desirable agronomic traits. The present invention also provides methods of making such plants and methods of using such plants to produce additional machine harvestable tomatillo plants.

Abstract: Detection and mitigation of signal conflict, such as a primary synchronization signal conflict, between broadcast cells in a wireless communication network is provided. Multiple broadcast cells may be provided in the network to provide sectors of coverage. A mobile communication device may operate within the network and attempt to attach to one or more of the broadcast cells. A synchronization signal conflict between neighboring broadcast cells may be identified and mitigated using one or more adjustments to the broadcast cells or signals emitted therefrom, which may allow for improved network performance, among other benefits.