Patents by Inventor Patrick Leamy
Patrick Leamy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230063323Abstract: The present disclosure provides tissue products produced from extracellular tissue matrices. The tissue products can include acellular extracellular matrices that have been treated in select areas to increase the compressive modulus of the matrix in the selected area while maintaining the ability to support cell growth and tissue regeneration. In addition, the tissue products can include collagen-containing materials that support tissue ingrowth along with a framework of collagenous or polymeric materials such that the combination has a desired compressive or tensile modulus and/or strength while maintaining the ability to support cell growth and tissue regeneration.Type: ApplicationFiled: May 25, 2022Publication date: March 2, 2023Inventors: Israel James Jessop, Mrinal Shah, Patrick Leamy
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Publication number: 20200237944Abstract: Systems for sterilization of tissues, including acellular tissue matrices, comprising a package having a portion permeable to supercritical carbon dioxide and a portion impermeable to moisture are described. Methods of sterilizing acellular tissue matrices from soft tissues or demineralized bone are provided.Type: ApplicationFiled: April 3, 2020Publication date: July 30, 2020Applicant: LifeCell CorporationInventors: Patrick Leamy, Qing-Qing Qiu, Michael S. Pohle, Jason Michael Pomerleau, Jerome Connor
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Publication number: 20190151507Abstract: Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix and/or to control the immunogenicity of the tissue matrix. The methods can comprise treatment with alcalase under conditions controlled to produce a desired pliability without unacceptable alteration in collagen structure.Type: ApplicationFiled: January 23, 2019Publication date: May 23, 2019Inventors: Yi Chen, Kai-Roy Wang, Patrick Leamy, Nimesh Kabaria, Hui Xu
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Patent number: 10207025Abstract: Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix and/or to control the immunogenicity of the tissue matrix. The methods can also comprise performing an assay to determine if contacting the at least one collagen-containing tissue matrix with a proteolytic enzyme has altered the at least one collagen-containing tissue matrix to reduce a human immune response to the tissue matrix. The methods can comprise treatment with alcalase under conditions controlled to produce a desired pliability without unacceptable alteration in collagen structure.Type: GrantFiled: September 5, 2014Date of Patent: February 19, 2019Assignee: LifeCell CorporationInventors: Yi Chen, Kai-Roy Wang, Patrick Leamy, Hui Xu, Nimesh Kabaria
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Publication number: 20160296652Abstract: Systems for sterilization of tissues, including acellular tissue matrices, comprising a package having a portion permeable to supercritical carbon dioxide and a portion impermeable to moisture are described. Methods of sterilizing acellular tissue matrices from soft tissues or demineralized bone are provided.Type: ApplicationFiled: June 17, 2016Publication date: October 13, 2016Inventors: Patrick Leamy, Qing-Qing Qiu, Michael S. Pohle, Jason Michael Pomerleau, Jerome Connor
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Publication number: 20160206784Abstract: The present disclosure provides tissue products produced from extracellular tissue matrices. The tissue products can include acellular extracellular matrices that have been treated in select areas to increase the compressive modulus of the matrix in the selected area while maintaining the ability to support cell growth and tissue regeneration. In addition, the tissue products can include collagen-containing materials that support tissue ingrowth along with a framework of collagenous or polymeric materials such that the combination has a desired compressive or tensile modulus and/or strength while maintaining the ability to support cell growth and tissue regeneration.Type: ApplicationFiled: January 20, 2016Publication date: July 21, 2016Inventors: Israel Jessop, Mrinal Shah, Patrick Leamy
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Publication number: 20140377833Abstract: Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix and/or to control the immunogenicity of the tissue matrix. The methods can also comprise performing an assay to determine if contacting the at least one collagen-containing tissue matrix with a proteolytic enzyme has altered the at least one collagen-containing tissue matrix to reduce a human immune response to the tissue matrix. The methods can comprise treatment with alcalase under conditions controlled to produce a desired pliability without unacceptable alteration in collagen structure.Type: ApplicationFiled: September 5, 2014Publication date: December 25, 2014Inventors: Yi Chen, Kai-Roy Wang, Patrick Leamy, Hui Xu
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Publication number: 20140193299Abstract: Systems for sterilization of tissues, including acellular tissue matrices, comprising a package having a portion permeable to supercritical carbon dioxide and a portion impermeable to moisture are described. Methods of sterilizing acellular tissue matrices from soft tissues or demineralized bone are provided.Type: ApplicationFiled: March 12, 2014Publication date: July 10, 2014Applicant: LifeCell CorporationInventors: Patrick Leamy, Qing-Qing Qiu, Michael S. Pohle, Jason Michael Pomerleau, James R. Connor
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Patent number: 8057595Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.Type: GrantFiled: November 3, 2009Date of Patent: November 15, 2011Assignee: Synthes USA, LLCInventors: Bryan Monro Armitage, Ira Ison, Mark Fulmer, Sean Kerr, Michael Lehmicke, Patrick Leamy, William Schiffer
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Publication number: 20100048763Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.Type: ApplicationFiled: November 3, 2009Publication date: February 25, 2010Inventors: Bryan Monro Armitage, Ira Ison, Mark Fulmer, Sean Kerr, Michael Lehmicke, Patrick Leamy, William Schiffer
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Patent number: 7628851Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.Type: GrantFiled: May 30, 2008Date of Patent: December 8, 2009Assignee: Synthes USA, LLCInventors: Bryan Monro Armitage, Ira C Ison, Mark Thomas Fulmer, Sean Hamilton Kerr, Michael Lehmicke, Patrick Leamy, William Schiffer
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Patent number: 7494950Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.Type: GrantFiled: September 7, 2004Date of Patent: February 24, 2009Assignees: Synthes (U.S.A.), Synthes GmbHInventors: Bryan Monro Armitage, Ira Ison, Mark Fulmer, Sean Kerr, Michael Lehmicke, Patrick Leamy, William Schiffer
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Publication number: 20080226691Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.Type: ApplicationFiled: May 30, 2008Publication date: September 18, 2008Inventors: Bryan Monro Armitage, Ira ISON, Mark FULMER, Sean KERR, Michael LEHMICKE, Patrick LEAMY, William SCHIFFER
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Publication number: 20050208094Abstract: The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of discrete fibers, optionally a flow additive, and optionally continuous reinforcing fibers or an array of organized fibers in the form of mesh. Advantageously, the discrete fibers have a specific aspect ratio (length/diameter) from about 50:1 to about 1000:1. The addition of a small amount of discrete fibers and/or the continuous reinforcing fibers or fiber mesh can cause drastic increases in certain mechanical properties including flexural strength, flexural toughness, and/or screw pullout strength.Type: ApplicationFiled: September 7, 2004Publication date: September 22, 2005Inventors: Bryan Armitage, Ira Ison, Mark Fulmer, Sean Kerr, Michael Lehmicke, Patrick Leamy, William Schiffer
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Publication number: 20050131458Abstract: A flowable, biodegradable endovascular embolic composition effective for embolizing a vascular defect consisting essentially of: (a) a biocompatible, biodegradable polymer or polymeric material forming composition; (b) a biocompatible embolic solvent for the polymer or polymer forming composition capable of diffusion into mammalian tissue; (c) biocompatible magnetic particles responsive to a magnetic field; wherein: the polymer or polymeric forming material and solvent are present in the composition in amounts and relative proportions such that (1) the composition is deliverable to a vascular defect site and (2) upon delivery to the site, solidifies into an embolic mass; and the magnetic particles are present in the composition in an amount sufficient to enable the composition being deliverable to the vascular site by a magnetic field. Also disclosed are methods and articles of manufacture embodying the above-described composition.Type: ApplicationFiled: August 9, 2004Publication date: June 16, 2005Inventors: Christopher Batich, Matthew Eadens, Robert Mericle, Matthew Burry, Courtney Watkins, Swadeshmukul Santra, Patrick Leamy
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Patent number: 5590245Abstract: An image processing method is carried out by a system (1) where a client system (2) automatically logs client data and retrieves image data to produce a job file which is automatically transmitted to a modem (10) of an image processing system (3). A control image processor (11) automatically monitors the job file and carries out routing operations and also supervisor notification operations to ensure efficient and effective implementation of the image processing method as required by the client. Each of the workstations (18, 19, 20) is capable of automatic configuration for particular job types by setting of image processing parameter values such as memory and virtual memory settings.Type: GrantFiled: August 24, 1994Date of Patent: December 31, 1996Assignee: Offset Studios LimitedInventors: Patrick Leamy, Alan Leamy, John Gillin