Abstract: A valve actuator that moves in a catheter assembly between a first position where a valve is closed and a second position where the valve is open, the valve actuator including a shaft portion at a distal end of the valve actuator that is configured to pierce the valve, a mating portion at a proximal end of the valve actuator that is configured to engage a Luer device, a diameter reduction region that connects the shaft portion and the mating portion, and a plurality of windows that extend through the valve actuator for flushing fluid, the plurality of windows being disposed in the diameter reduction region, wherein each of the plurality of windows does not extend a full length of the diameter reduction region.

Abstract: Provided herein are compounds and compositions thereof for modulating S1P5. In some embodiments, the compounds and compositions are provided for treatment of neurological diseases.

Abstract: The present invention refers to a data management unit for supporting health control comprising a display (162), a processor (140) adapted to receive a user-selectable group of measurement values of a plurality of measurement values of a physiological parameter, for example a blood glucose level, to calculate at least one derived value (501a, 503a, 506a) from the group of measurement values and to determine for each derived value (501a, 503a, 506a) a corresponding rating value and/or a corresponding trend value, a trend indicator (164), wherein the trend indicator is adapted to indicate different trend categories on the display (162), for example an increasing trend, a steady trend and a decreasing trend, as a respective graphical picture (503d), a color indicator (166), wherein the color indicator is adapted to indicate an area (501b, 503b, 506b) with at least one of two different colors on the display (162), for example a red color and a green color, wherein the display (162) is adapted to display the at le

Abstract: Described are embodiments for allowing the negotiation of a continuous presence layout. Specifically, in embodiments, an offer is generated by a client that includes attributes for displaying continuous presence video information. The attributes include, in some embodiments, one or more window identifiers, one or more bandwidth limit identifiers, one or more group numbers, and/or one or more ranks. The offer is sent to a server which transmits an answer to the offer. Once the attributes for the continuous presence layout has been negotiated, the server uses the attributes to format video content sent to the client.

Abstract: Described are embodiments for allowing the negotiation of a continuous presence layout. Specifically, in embodiments, an offer is generated by a client that includes attributes for displaying continuous presence video information. The attributes include, in some embodiments, one or more window identifiers, one or more bandwidth limit identifiers, one or more group numbers, and/or one or more ranks. The offer is sent to a server which transmits an answer to the offer. Once the attributes for the continuous presence layout has been negotiated, the server uses the attributes to format video content sent to the client.