Abstract: Systems and methods are provided for controlling the authentication or authorization of a mobile device user for enabling access to the resources or functionality associated with an application or service executable at the user's mobile device. The user or user's mobile device may be automatically authenticated or authorized to access application or system resources at the device when the current geographic location of the user's mobile device is determined to be within a preauthorized zone, e.g., based on a predetermined geo-fence corresponding to the preauthorized zone. A security level or amount of authorization credentials required to authorize a user for data access may be varied according any of a plurality of security levels, when the current or last known geographic location of the user's mobile device is determined to be outside the preauthorized zone.

Abstract: Systems and methods are provided for determining in real-time geographic areas having a threshold level of content consumption and deploying dynamic geo-fences to contain these geographic areas. These dynamic geo-fences provide a means for timing message notifications in order to optimize the chances of delivering targeted content to a mobile device user based on the current geographic location of the user's device relative to a threshold level of content consumption area. As mobile device users may be more likely to launch a client application in a place where other users are currently consuming content, a general message notification sent to the user's device located in a dynamic geo-fence created based on real-time content consumption, may increase the likelihood that the user will launch the client application and thereby, allow targeted content to be delivered to the user's mobile device.

Abstract: Systems and methods are provided for timing message notifications to be provided to mobile device users based on their geographic locations with respect to geographic areas associated with a threshold level of content consumption. The timing of message notifications may be controlled in order to optimize the chances of delivering targeted content to a mobile device user based on the current geographic location of the user's device relative to a threshold level of content consumption area. As mobile device users may be more likely to launch a client application in a place where other users are currently consuming content, a general message notification sent to the user's device located in a geographic area associated with a threshold level of content consumption, may increase the likelihood that the user will launch the client application and thereby, allow targeted content to be delivered to the user's mobile device.

Abstract: Systems and methods are provided for timing message notifications to be provided to mobile device users based on their geographic locations with respect to geographic areas associated with a threshold level of content consumption. The timing of message notifications may be controlled in order to optimize the chances of delivering targeted content to a mobile device user based on the current geographic location of the user's device relative to a threshold level of content consumption area. As mobile device users may be more likely to launch a client application in a place where other users are currently consuming content, a general message notification sent to the user's device located in a geographic area associated with a threshold level of content consumption, may increase the likelihood that the user will launch the client application and thereby, allow targeted content to be delivered to the user's mobile device.

Abstract: Systems and methods are provided for controlling the authentication or authorization of a mobile device user for enabling access to the resources or functionality associated with an application or service executable at the user's mobile device. The user or user's mobile device may be automatically authenticated or authorized to access application or system resources at the device when the current geographic location of the user's mobile device is determined to be within a preauthorized zone, e.g., based on a predetermined geo-fence corresponding to the preauthorized zone. A security level or amount of authorization credentials required to authorize a user for data access may be varied according any of a plurality of security levels, when the current or last known geographic location of the user's mobile device is determined to be outside the preauthorized zone.

Abstract: Systems and methods are provided for controlling the authentication or authorization of a mobile device user for enabling access to the resources or functionality associated with an application or service executable at the user's mobile device. The user or user's mobile device may be automatically authenticated or authorized to access application or system resources at the device when the current geographic location of the user's mobile device is determined to be within a preauthorized zone, e.g., based on a predetermined geo-fence corresponding to the preauthorized zone. A security level or amount of authorization credentials required to authorize a user for data access may be varied according any of a plurality of security levels, when the current or last known geographic location of the user's mobile device is determined to be outside the preauthorized zone.

Abstract: Systems and methods are provided for enabling access to digital content based on geographic locations visited by mobile device users. One method includes receiving a promotion associated with premium digital content, access information, and one or more locations in which the premium digital content is accessible.

Abstract: Systems and methods are disclosed for electronic distribution of electronic content. The method includes retrieving data indicating transmission of electronic content to a plurality of electronic devices within a geographical zone extending between an inner boundary extending around a target location and an outer boundary extending around the target location; receiving data indicating presence of one of the plurality of electronic devices in a target geographical zone, the target geographical zone being located within the inner boundary; determining a time difference between transmission of the electronic content to the one of the plurality of electronic devices and the one of the plurality of electronic devices' presence in the target geographical zone; and determining an electronic device conversion occurred when the time difference is less than a threshold period of time associated with the electronic content.

Abstract: Systems and methods are provided for determining release weights for geographic locations and specific times for selected users, and optimizing the timing of message notifications for a mobile device based on those release weights. The release weights may be determined based 1) generalized factors, 2) factors individualized for a particular mobile device user, and/or 3) real-time factors. These release weights are calculated to represent a user's likeliness to launch a client application from a message notification at a given time and geographic location.

Abstract: Systems and methods are provided for determining in real-time geographic areas having a threshold level of content consumption and deploying dynamic geo-fences to contain these geographic areas. These dynamic geo-fences provide a means for timing message notifications in order to optimize the chances of delivering targeted content to a mobile device user based on the current geographic location of the user's device relative to a threshold level of content consumption area. As mobile device users may be more likely to launch a client application in a place where other users are currently consuming content, a general message notification sent to the user's device located in a dynamic geo-fence created based on real-time content consumption, may increase the likelihood that the user will launch the client application and thereby, allow targeted content to be delivered to the user's mobile device.

Abstract: Systems and methods are provided for increasing sales profits by dynamically determining a promotion associated with a coupon. The promotion may be determined and delivered to a mobile device once the mobile device is in a geographic location associated with the coupon. By allowing advertisers to change or decide promotions in real-time, demand may be smoothed and profits may be maximized. When the mobile device is in the location associated with the coupons, advertisers can use a variety of factors including location, time of day, current sales or redemption data, or information known about the mobile device to set or adjust an ideal promotion for the current situation.

Abstract: Systems and methods are provided for timing message notifications to be provided to mobile device users based on their geographic locations with respect to geographic areas associated with a threshold level of content consumption. The timing of message notifications may be controlled in order to optimize the chances of delivering targeted content to a mobile device user based on the current geographic location of the user's device relative to a threshold level of content consumption area. As mobile device users may be more likely to launch a client application in a place where other users are currently consuming content, a general message notification sent to the user's device located in a geographic area associated with a threshold level of content consumption, may increase the likelihood that the user will launch the client application and thereby, allow targeted content to be delivered to the user's mobile device.

Abstract: Systems and methods are disclosed for electronic distribution of electronic content. The method includes receiving, from an advertiser or content provider, a request to transmit electronic content to a plurality of electronic devices of a desired subset of individuals, wherein the electronic content relates to a target location of the advertiser or content provider; identifying a geographical zone extending between an inner boundary around the target location and an outer boundary around the target location; receiving an indication that one of the plurality of electronic devices of the subset of individuals is present in the geographical zone based on determining that the one of the plurality of electronic devices is located within the outer boundary but not within the inner boundary; and transmitting electronic content to the electronic device of the one of the subset of individuals in the population, the electronic content relating to the target location.

Abstract: Systems and methods are provided for controlling the authentication or authorization of a mobile device user for enabling access to the resources or functionality associated with an application or service executable at the user's mobile device. The user or user's mobile device may be automatically authenticated or authorized to access application or system resources at the device when the current geographic location of the user's mobile device is determined to be within a preauthorized zone, e.g., based on a predetermined geo-fence corresponding to the preauthorized zone. A security level or amount of authorization credentials required to authorize a user for data access may be varied according any of a plurality of security levels, when the current or last known geographic location of the user's mobile device is determined to be outside the preauthorized zone.

Abstract: Systems and methods are disclosed for electronic distribution of electronic content. The method may include receiving, from an advertiser or content provider, a request to transmit electronic content to a plurality of electronic devices of a desired subset of individuals. The electronic content may relate to a target location affiliated with the advertiser or content provider. The method also may include retrieving population density data for the target location and surrounding area, and correlating the subset of individuals with the population density. In addition, the method also may identifying a geographical zone extending from the target location to a perimeter location. The zone may have a size based on the population density correlated with the subset of individuals. The method my further include receiving an indication that the electronic device of a user has entered the geographical zone, and transmitting electronic content to the electronic device of the user.

Abstract: Systems and methods are disclosed for online distribution of content. The method may include, receiving a request to publish content on the electronic device relating to a target location. The request may include at least one threshold travel parameter to the target location. The method also may include identifying one or more perimeter locations at the at least one threshold travel parameter and generating a zone extending from the one or more locations to the target location and including one or more routes. In addition, the method may include receiving an indication that the electronic device has entered the zone, transmitting content to the user's electronic device relating to the target location.

Abstract: The invention describes methods and compositions for alleviating recurrent medical afflictions for which anxiety may cause or exacerbate the affliction. A subject suffering from the affliction is treated with a combination of a pharmaceutical that enhances learning, and a second pharmaceutical recognized to be useful for treatment of the affliction. Representative afflictions include insomnia, erectile dysfunction, female sexual dysfunction, neuropathic pain, attention deficit disorder, and depression.

Abstract: The present invention provides a method for producing physiologically active human Interleukin-18 (“IL-18”).

Abstract: The present invention provides a method for producing physiologically active human Interleukin-18 (“IL-18”).

Abstract: The present invention includes novel ligands which may be utilized as part of a catalyst system. A catalyst system of the present invention is a transition metal-ligand complex. In particular, the catalyst system includes a transition metal component and a ligand component comprising a Nitrogen atom and/or functional groups comprising a Nitrogen atom, generally in the form of an imine functional group. In certain embodiments, the ligand component may further comprise a phosphorous atom. Preferred ligand components are bidentate (bind to the transition metal at two or more sites) and include a nitrogen-transition metal bond. The transition metal-ligand complex is generally cationic and associated with a weakly coordinating anion. A catalyst system of the present invention may further comprise a Lewis or Bronsted acid. The Lewis or Bronsted acid may be complexed with the ligand component of the transition metal-ligand complex.