Abstract: An apparatus includes a catheter and an end effector. At least a portion of the catheter is sized and configured to fit within a lumen of a human cardiovascular system. The end effector is positioned at a distal end of the catheter. The end effector includes an expandable assembly and at least one flex circuit. The expandable assembly is configured to transition between a non-expanded state and an expanded state. The expandable assembly includes at least one deformable strut or cage. Each flex circuit includes a flexible substrate secured, without an adhesive, to the expandable assembly and an electrode secured to the flexible substrate. The expandable assembly in the expanded state is configured to urge the electrode into contact with tissue. The electrode has a fishbone-like configuration that defines a longitudinally elongated portion and a plurality of fingers extending transversely from the longitudinally elongated portion.

Abstract: The present disclosure provides a diagnostic and treatment system for communicating with a device to obtain diagnostic input, generating one or more diagnostic evaluations based on the diagnostic input, and generating a subset of differential diagnoses based on the answers to the diagnostic questions and results corresponding to the one or more diagnostic evaluations. The system also receives a selected diagnosis from the subset of differential diagnoses and generates a subset of treatment options based on the selected diagnosis.

Abstract: A treatment instrument can include a fluid platform comprising a chamber and an access port to provide fluid communication between a treatment region of the tooth and the chamber, the chamber having a central axis. The treatment instrument can include a first fluid supply port disposed to direct a fluid stream of a first material into the chamber along a stream axis non-parallel to the central axis. The treatment instrument can include a second supply port distal the first fluid supply port, the second supply port disposed to direct a second material to be entrained with the fluid stream into the chamber.

Abstract: A spine of an electrode assembly is constructed by simultaneously deploying a plurality of individual bobbins of lead wire radially around the longitudinal axis of a polymeric tube. A free end of lead wire from each bobbin is electrically connected to a respective electrode and the electrodes are sequentially installed from a distal first location on the polymeric tube to a proximal location. Each lead wire may be helically wound around the polymeric tube between the electrode to which the lead wire is electrically connected and a proximally adjacent electrode, such that each lead wire between adjacent pairs of electrodes has an alternating direction of winding.

Abstract: Systems and methods are disclosed for providing and using an ablation catheter. The catheter may include a ring electrode having a contact force sensor that provides signals to a system controller to indicate whether the ablation electrode is in contact with the tissue to be ablated as well as how much of the ablation electrode is in contact with the tissue.

Abstract: An apparatus includes a catheter and an end effector. At least a portion of the catheter is sized and configured to fit within a lumen of a human cardiovascular system. The end effector is positioned at a distal end of the catheter. The end effector includes an expandable assembly and at least one flex circuit. The expandable assembly is configured to transition between a non-expanded state and an expanded state. The expandable assembly includes at least one deformable strut or cage. Each flex circuit includes a flexible substrate secured, without an adhesive, to the expandable assembly and an electrode secured to the flexible substrate. The expandable assembly in the expanded state is configured to urge the electrode into contact with tissue. The electrode has a fishbone-like configuration that defines a longitudinally elongated portion and a plurality of fingers extending transversely from the longitudinally elongated portion.

Abstract: A spine of an electrode assembly is constructed by simultaneously deploying a plurality of individual bobbins of lead wire radially around the longitudinal axis of a polymeric tube. A free end of lead wire from each bobbin is electrically connected to a respective electrode and the electrodes are sequentially installed from a distal first location on the polymeric tube to a proximal location. Each lead wire may be helically wound around the polymeric tube between the electrode to which the lead wire is electrically connected and a proximally adjacent electrode, such that each lead wire between adjacent pairs of electrodes has an alternating direction of winding.

Abstract: Systems and methods are disclosed for providing and using an ablation catheter. The catheter may include a ring electrode having a contact force sensor that provides signals to a system controller to indicate whether the ablation electrode is in contact with the tissue to be ablated as well as how much of the ablation electrode is in contact with the tissue.

Abstract: A catheter has an electrode assembly adapted for use on an ostium and a stabilizing assembly movable between a stowed position within the catheter and a deployed position in the tubular region of the ostium. The stabilizing assembly has a balloon member that can be extended distally into the tubular region and inflated to wedge itself in the tubular region for anchoring the electrode assembly. The balloon member is mounted on an elongated extender that extends through the catheter and is provided with longitudinal movement to advance and withdraw the balloon between the stowed and deployed positions.

Abstract: Described herein is an assembly and alignment tool for aligning leaflets of a soft leaflet prosthetic heart valve and fix the leaflets to each other and/or to a wireform or stent. In embodiments, the assembly or alignment tool includes a mandrel configured to support one or more leaflets of a prosthetic valve. The mandrel includes at least one suture hole disposed on the surface thereof to allow a needle to pass through when sewing the one or more leaflets to a wireform.