Patents by Inventor Patrick R. Errada

Patrick R. Errada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for agents which alter G-protein coupled receptor activity
    Patent number: 6291177
    Abstract: The invention relates to a novel transformed yeast cell comprising a first heterologous nucleic acid sequence encoding a G-protein coupled receptor; and second nucleic acid sequence encoding the yeast G&agr; subunit protein Gpa2; and an optional third heterologous nucleic acid sequence encoding a reporter protein. The G-protein coupled receptor can bind ligand thereby altering the activity of Gpa2 and cellular levels of second messenger molecules and ultimately the activity of target genes. The transformed yeast cell can be used, for example, in in vitro high throughput assays to screen for agonists and antagonists of G-protein coupled receptor ligand activity.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: September 18, 2001
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Kevin T. Madden, Patrick R. Errada, Carlos J. Gimeno
  • Assay for agents which alter G-protein coupled receptor activity
    Patent number: 6280934
    Abstract: The invention relates to a novel transformed yeast cell comprising a first heterologous nucleic acid sequence encoding a G-protein coupled receptor; and second nucleic acid sequence encoding the yeast G&agr; subunit protein Gpa2; and an optional third heterologous nucleic acid sequence encoding a reporter protein. The G-protein coupled receptor can bind ligand thereby altering the activity of Gpa2 and cellular levels of second messenger molecules and ultimately the activity of target genes. The transformed yeast cell can be used, for example, in in vitro high throughput assays to screen for agonists and antagonists of G-protein coupled receptor ligand activity.
    Type: Grant
    Filed: May 13, 1998
    Date of Patent: August 28, 2001
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Kevin T. Madden, Patrick R. Errada, Carlos J. Gimeno
  • Tub interactor (TI) polypeptides and uses therefor
    Patent number: 6147192
    Abstract: The present invention provides a novel tub interactor (TI) polypeptides, as well as TI fusion polypeptides, and antigenic peptides.
    Type: Grant
    Filed: February 18, 1999
    Date of Patent: November 14, 2000
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Carlos J. Gimeno, Patrick R. Errada
  • Genes encoding proteins that interact with the tub protein
    Patent number: 5955306
    Abstract: The present invention relates to the discovery of novel genes encoding Tub interactor (TI) polypeptides. Therapeutics, diagnostics and screening assays based on these molecules are also disclosed.
    Type: Grant
    Filed: July 21, 1997
    Date of Patent: September 21, 1999
    Assignee: Millenium Pharmaceuticals, Inc.
    Inventors: Carlos J. Gimeno, Patrick R. Errada