Abstract: A sharps disposal system (2) includes a fiberboard container (6) mounted to a wall (8) by a lockable cage (4). The container has an entrance opening (70) formed through the top (20), sized for the deposit of sharps into its interior. A baffle (60) extends within the interior from the back downwardly and forwardly and is sized and positioned to discourage manual access to the interior while directing sharps into the interior. The container also includes a lid (84) hinged to the top for movement between stable opened and closed positions to permit one hand operation when opened. For disposal the lid is secured to the top using a foam adhesive strip (104) to provide a secure, substantially leakproof seal. The container is coated on the inside surface with a hydrophobic material and has the seams and corners sealed to make the interior of the container substantially leakproof. A view port (50) can be provided to permit the user to determine when the container is full.