Abstract: In overview, the technology is primarily directed to the implementation of linked gaming in respect of a plurality of gaming machines. In particular, a controller device is disclosed, this controller device being adapted to enable the management of a plurality of linked games via a single piece of hardware. This is achieved in part by virtualization of jackpot controllers within the controller device. More specifically, a user is enabled to configure a plurality of virtual jackpot controllers by way of interaction with a graphical user interface, and select compatible electronic gaming machines to participate in a linked game provided by a given one of the virtual jackpot controllers.

Abstract: Technology described herein includes an arrangement whereby a hardware-based solution is implemented to enable mirroring of NVRAM data in a master server directly to NVRAM in a sleeper server. Both the master server and sleeper server implement a like motherboard unit, which is configured to implement the mirroring technology. That is, the roles of master and sleeper may be reversed. The master server includes a hardware module that monitors (but does not affect) NVRAM operations at the master server, and replicates those operations via a high speed communications link, such as a fiber optic link, to the sleeper server. The term “high speed communications link” refers to a link with at least 2.5 gigabit speed, and preferably at least 5 gigabit speed. The sleeper server is configured to, when in sleeper mode, suspend control of its own NVRAM module. Instead, the NVRAM module is controlled by a module that is configured to receive NVRAM operations via the fiber optic link, and apply those operations.

Abstract: There is provided a grouping for classifying a gastric cancer tumor sample obtained from a patient suffering or suspected to suffer from gastric cancer, wherein the grouping comprises an invasive subtype, a proliferative subtype and a metabolic subtype. There is also provided a predictor and methods of using the grouping.

Abstract: The present invention relates to a pharmaceutical composition comprising an anti-cancer drug and an inhibitor of bone morphogenetic protein 4 (BMP-4) or its gene expression. The present invention also relates to methods of treating cancer and prognostic methods.

Abstract: In overview, the technology is primarily directed to the implementation of linked gaming in respect of a plurality of gaming machines. In particular, a controller device is disclosed, this controller device being adapted to enable the management of a plurality of linked games via a single piece of hardware. This is achieved in part by virtualization of jackpot controllers within the controller device. More specifically, a user is enabled to configure a plurality of virtual jackpot controllers by way of interaction with a graphical user interface, and select compatible electronic gaming machines to participate in a linked game provided by a given one of the virtual jackpot controllers.

Abstract: Fluorescent screens and display systems and devices based on such screens using at least one excitation optical beam to excite one or more fluorescent materials on a screen which emit light to form images. The fluorescent materials may include phosphor materials and non-phosphor materials such as quantum dots. A screen may include a multi-layer dichroic layer.

Abstract: The present invention in one aspect relates to a method for treating cancer or enhancing a cancer treatment, the method comprising inhibiting the expression of an oligonucleotide encoding for a protein selected from the group consisting of OLFM4, SP5, TOB1, ARID1A, FBN1 and HAT1, by administering to a mammal in need of cancer treatment an effective amount of at least one silencing oligonucleotide comprising a binding motif for binding to the oligonucleotide encoding for a protein.

Abstract: The invention provides an in vitro method for predicting clinical outcome of a patient affected with a non-small cell lung carcinoma (NSCLC), which method comprises determining the expression level of at least 8 genes in a biological sample of said patient.

Abstract: The invention relates to methods for diagnosis and prognosis of gastric cancer. The approach described herein can distinguish intestinal-type gastric cancer (G-INT) from diffuse-type gastric cancer (G-DIF). The genomic expression signatures of G-INT and G-DIF define two major sets of genes. A diagnosis of gastric cancer G-INT and G-DIF can be made on the basis of the expression levels of these genes. This can lead to a better prognosis and treatment of gastric cancer.

Abstract: A method of treating or preventing a gastrointestinal cancer by inhibiting expression of a CD44-SLC1A2 fusion gene or a functional variant thereof, or by inhibiting the activity of a fusion protein expressed by the CD44-SLC1A2 fusion gene or the functional variant thereof.

Abstract: One embodiment described herein is directed to a method practiced in a computing environment. The method includes acts for determining test suite effectiveness for testing for concurrency problems and/or product faults. The method includes identifying a plurality of synchronization primitives in a section of implementation source code. One or more of the synchronization primitives are iteratively modified and a same test suite is run for each iteration. For each iteration, a determination is made whether or not the test suite returns an error as a result of modifying one or more synchronization primitives. When the test suite does not return an error, the method includes providing to a user an indication which indicates at least one of a test adequacy hole for the test suite; an implementation source code fault; or an equivalent mutant of the implementation source code.

Abstract: The invention provides an in vitro method for predicting clinical outcome of a patient affected with a non-small cell lung carcinoma (NSCLC), which method comprises determining the expression level of at least 8 genes in a biological sample of said patient.

Abstract: One embodiment described herein is directed to a method practiced in a computing environment. The method includes acts for determining test suite effectiveness for testing for concurrency problems and/or product faults. The method includes identifying a plurality of synchronization primitives in a section of implementation source code. One or more of the synchronization primitives are iteratively modified and a same test suite is run for each iteration. For each iteration, a determination is made whether or not the test suite returns an error as a result of modifying one or more synchronization primitives. When the test suite does not return an error, the method includes providing to a user an indication which indicates at least one of a test adequacy hole for the test suite; an implementation source code fault; or an equivalent mutant of the implementation source code.

Abstract: Fluorescent screens and display systems and devices based on such screens using at least one excitation optical beam to excite one or more fluorescent materials on a screen which emit light to form images. The fluorescent materials may include phosphor materials and non-phosphor materials such as quantum dots. A screen may include a multi-layer dichroic layer.

Abstract: Fluorescent screens and display systems and devices based on such screens using at least one excitation optical beam to excite one or more fluorescent materials on a screen which emit light to form images. The fluorescent materials may include phosphor materials and non-phosphor materials such as quantum dots. A screen may include a multi-layer dichroic layer.

Abstract: A device includes a scan circuit including a scan chain. The scan chain includes a first plurality of scan cells that receive a first scan clock signal in a first clock domain. A second plurality of scan cells receives a second scan clock signal in a second clock domain. A scan clock source generates the first scan clock signal and the second scan clock signal, and selectively inverts the first scan clock signal and the second scan clock signal based on an operating mode of the first plurality of scan cells and the second plurality of scan cells, respective flip-flop arrangements of the first clock domain and the second clock domain.

Abstract: Fluorescent screens and display systems and devices based on such screens using at least one excitation optical beam to excite one or more fluorescent materials on a screen which emit light to form images. The fluorescent materials may include phosphor materials and non-phosphor materials such as quantum dots. A screen may include a multi-layer dichroic layer.

Abstract: In one embodiment, an apparatus comprises a scan circuit including at least a first and a second clock domain and a scan chain having a first plurality of scan cells positioned in the first clock domain and a second plurality of scan cells positioned in the second clock domain. A scan clock source, coupled to the scan chain, generates a first scan clock signal to the first plurality of scan cells and a second scan clock signal to the second plurality of scan cells. The first and the second clock signals have an inverted relationship.

Abstract: The invention provides materials and methods for classifying breast cancer in patients. Particularly there is provided a novel gene expression signature which acts as a predictive signature for response to treatment including hormonal therapies (e.g. tamoxifen) and chemotherapy.