Patents by Inventor Patton E. Garay

Patton E. Garay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS
    Publication number: 20230279083
    Abstract: The present specification discloses SNAP-25 compositions, methods of making ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing ?-BoNT/A antibodies.
    Type: Application
    Filed: September 29, 2022
    Publication date: September 7, 2023
    Inventors: Ester Fernandez-Salas, Joanne Wang, Patton E. Garay, Lina Wong, D. Dianne Hodges, Kei Roger Aoki
  • IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS
    Publication number: 20230235031
    Abstract: The present specification discloses SNAP-25 compositions, methods of making ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing ?-BoNT/A antibodies.
    Type: Application
    Filed: August 17, 2022
    Publication date: July 27, 2023
    Inventors: Ester Fernandez-Salas, Joanne Wang, Patton E. Garay, Lina Wong, D. Dianne Hodges, Kei Roger Aoki
  • Immuno-based botulinum toxin serotype A activity assays
    Patent number: 11332518
    Abstract: The present specification discloses SNAP-25 compositions, methods of making ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing ?-BoNT/A antibodies.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: May 17, 2022
    Assignee: Allergan, Inc.
    Inventors: Ester Fernandez-Salas, Joanne Wang, Patton E. Garay, Lina Wong, D. Dianne Hodges, Kei Roger Aoki
  • IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS
    Publication number: 20220144925
    Abstract: The present specification discloses SNAP-25 compositions, methods of making ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing ?-BoNT/A antibodies.
    Type: Application
    Filed: January 11, 2022
    Publication date: May 12, 2022
    Inventors: Ester Fernandez-Salas, Joanne Wang, Patton E. Garay, Lina Wong, D. Dianne Hodges, Kei Roger Aoki
  • Immuno-based botulinum toxin serotype A activity assays
    Patent number: 11261240
    Abstract: The present specification discloses SNAP-25 compositions, methods of making ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing ?-BoNT/A antibodies.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: March 1, 2022
    Assignee: Allergan, Inc.
    Inventors: Ester Fernandez-Salas, Joanne Wang, Patton E. Garay, Lina Wong, D. Diane Hodges, Kei Roger Aoki
  • METHODS OF TREATING CANCER USING OPIOD RETARGETED ENDOPEPIDASES
    Publication number: 20130230502
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
    Type: Application
    Filed: November 20, 2012
    Publication date: September 5, 2013
    Applicant: ALLERGAN, INC.
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Dean G. Stathakis, Joseph Francis, Kei Roger Aoki, Ester Fernandez-Salas
  • Methods of Treating Cancer Using Growth Factor Retargeted Endopeptidases
    Publication number: 20130195838
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
    Type: Application
    Filed: August 9, 2012
    Publication date: August 1, 2013
    Applicant: ALLERGAN, INC.
    Inventors: Birgitte P.S. JACKY, Patton E. Garay, Yanira Molina, Dean G. Stathakis, Joseph Francis, Kei Roger Aoki, Ester Fernandez-Salas, Lance E. Steward, Sanjiv Ghanshani, Terrence J. Hunt
  • Botulinum toxin screening assays
    Patent number: 8497081
    Abstract: Methods for detecting BoNT/A activity in a sample, methods for screening molecules able to compete with BoNT/A receptor binding, methods for reducing BoNT/A activity in a human and methods of marketing a neurotoxin capable of selectively binding to a FGFR2, a FGFR3, a SV2, or any combination thereof, to a governmental or regional regulatory authority.
    Type: Grant
    Filed: May 20, 2009
    Date of Patent: July 30, 2013
    Assignee: Allergan, Inc.
    Inventors: Ester Fernandez-Salas, Birgitte P. S. Jacky, Patton E. Garay, Kei Roger Aoki
  • IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS
    Publication number: 20130040368
    Abstract: The present specification discloses SNAP-25 compositions, methods of making ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, ?-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing ?-BoNT/A antibodies.
    Type: Application
    Filed: October 11, 2012
    Publication date: February 14, 2013
    Applicant: ALLERGAN, INC.
    Inventors: Ester Fernandez-Salas, Joanne Wang, Patton E. Garay, Lina S. Wong, D. Dianne Hodges, Kei Roger Aoki
  • Botulinum toxin screening assays
    Patent number: 8257914
    Abstract: Methods for detecting BoNT/A activity in a sample, methods for screening molecules able to compete with BoNT/A receptor binding, methods for reducing BoNT/A activity in a human and methods of marketing a neurotoxin capable of selectively binding to FGFR3 to a governmental or regional regulatory authority.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: September 4, 2012
    Assignee: Allergan, Inc.
    Inventors: Ester Fernandez-Salas, Patton E. Garay, Kei Roger Aoki
  • Methods of Inhibiting Aberrant Blood Vessel Formation Using Opioid Retargeted Endpeptidases
    Publication number: 20120207734
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating a disease or disorder associated with aberrant new blood vessel formation in a mammal using such TVEMP compositions.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 16, 2012
    Applicant: ALLERGAN, INC.
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Joseph Francis, Lance E. Steward, Sanjiv Ghanshani, Terrence J. Hunt, Kei Roger Aoki, Ester Fernandez-Salas
  • Treating a Disease of Hyperproliferation Using Retargeted Endopeptidases
    Publication number: 20120207733
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer or a disease of hyperproliferation in a mammal using such TVEMP compositions.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 16, 2012
    Applicant: ALLERGAN, INC.
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Joseph Francis, Lance E. Steward, Sanjiv Ghanshani, Terrence J. Hunt, Kei Roger Aoki, Ester Fernandez-Salas
  • Inhibiting Aberrant Blood Vessel Formation Using Retargeted Endopeptidases
    Publication number: 20120207743
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating a disease or disorder associated with aberrant new blood vessel formation in a mammal using such TVEMP compositions.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 16, 2012
    Applicant: ALLERGAN, INC.
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Joseph Francis, Lance E. Steward, Sanjiv Ghanshani, Terrence J. Hunt, Kei Roger Aoki, Ester Fernandez-Salas
  • Treatments Using PSMA Ligand Endopeptidases
    Publication number: 20120207742
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating a prostate cancer, a benign prostatic hyperplasia, and/or neovascularization or pathological angiogenesis associated with a cancer in a mammal using such TVEMP compositions.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 16, 2012
    Applicant: ALLERGAN, INC.
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Joseph Francis, Lance E. Steward, Sanjiv Ghanshani, Terrence J. Hunt, George Sachs, Kei Roger Aoki, Ester Fernandez-Salas
  • Inhibiting Aberrant Blood Vessel Formation Using Growth Factor Retargeted Endopeptidases
    Publication number: 20120207704
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating a disease or disorder associated with aberrant new blood vessel formation in a mammal using such TVEMP compositions.
    Type: Application
    Filed: February 13, 2012
    Publication date: August 16, 2012
    Applicant: ALLERGAN, INC.
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Joseph Francis, Lance E. Steward, Sanjiv Ghanshani, Terrence J. Hunt, Kei Roger Aoki, Ester Fernandez-Salas
  • Methods of Treating Cancer Using Tachykinin Retargeted Endopepidases
    Publication number: 20110110911
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
    Type: Application
    Filed: August 16, 2010
    Publication date: May 12, 2011
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Dean G. Stathakis, Joseph Francis, Kei Roger Aoki, Ester Fernandez-Salas
  • METHODS OF TREATING CANCER USING NEUROTROPHIN RETARGETED ENDOPEPTIDASES
    Publication number: 20110070215
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
    Type: Application
    Filed: August 16, 2010
    Publication date: March 24, 2011
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Dean G. Stathakis, Joseph Francis, Kei Roger Aoki, Ester Fernandez-Salas
  • Methods of Treating Cancer Using Galanin Retargeted Endopepidases
    Publication number: 20110070211
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
    Type: Application
    Filed: August 13, 2010
    Publication date: March 24, 2011
    Inventors: BIRGITTE P.S. JACKY, PATTON E. GARAY, YANIRA MOLINA, DEAN G. STATHAKIS, JOSEPH FRANCIS, KEI ROGER AOKI, ESTER FERNANDEZ-SALAS
  • Methods of Treating Cancer Using Glucagon-Like Hormone Retargeted Endopeptidases
    Publication number: 20110070212
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
    Type: Application
    Filed: August 16, 2010
    Publication date: March 24, 2011
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Dean G. Stathakis, Joseph Francis, Kei Roger Aoki, Ester Fernandez-Salas
  • Methods of Treating Cancer Using Growth Factor Retargeted Endopeptidases
    Publication number: 20110070186
    Abstract: The present specification discloses TVEMPs, compositions comprising such TVEMPs and methods of treating cancer in a mammal using such TVEMP compositions.
    Type: Application
    Filed: August 16, 2010
    Publication date: March 24, 2011
    Inventors: Birgitte P.S. Jacky, Patton E. Garay, Yanira Molina, Dean G. Stathakis, Joseph Francis, Kei Roger Aoki, Ester Fernandez-Salas