Patents by Inventor Pau Sancho-Bru

Pau Sancho-Bru has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for differentiating cells into hepatic stellate cells
    Patent number: 11492596
    Abstract: The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other applications, for treatment of liver deficiencies, liver metabolism studies, and liver toxicity studies, fibrogenic studies, or to support hepatocyte function in co-culture setting.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: November 8, 2022
    Assignees: Katholieke Universiteit Leuven, Institut D'Investigacions Biomediques August PI | Sunyer (IDIBAPS)
    Inventors: Catherine Verfaillie, Ruben Boon, Pau Sancho Bru, Mar Col Loperena, Luis Perea Sanchez
  • METHODS FOR DIFFERENTIATING CELLS INTO HEPATIC STELLATE CELLS
    Publication number: 20200248146
    Abstract: The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other applications, for treatment of liver deficiencies, liver metabolism studies, and liver toxicity studies, fibrogenic studies, or to support hepatocyte function in co-culture setting.
    Type: Application
    Filed: December 1, 2016
    Publication date: August 6, 2020
    Applicants: Katholieke Universiteit Leuven, Institut D'Investigacions Biomediques August PI I Sunyer (IDIBAPS)
    Inventors: Catherine Verfaillie, Ruben Boon, Pau Sancho Bru, Mar Col Loperena, Luis Perea Sanchez
  • Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the method, and methods for using the cells
    Patent number: 9777258
    Abstract: The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype and cells that express a hepatic sinusoidal endothelial phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other things, for treatment of liver deficiency, liver metabolism studies, and liver toxicity studies.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: October 3, 2017
    Assignee: Katholieke Universiteit Leuven
    Inventors: Pau Sancho-Bru, Catherine M. Verfaillie
  • METHODS FOR DIFFERENTIATING CELLS INTO HEPATIC STELLATE CELLS AND HEPATIC SINUSOIDAL ENDOTHELIAL CELLS, CELLS PRODUCED BY THE METHOD, AND METHODS FOR USING THE CELLS
    Publication number: 20160145570
    Abstract: The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype and cells that express a hepatic sinusoidal endothelial phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other things, for treatment of liver deficiency, liver metabolism studies, and liver toxicity studies.
    Type: Application
    Filed: June 25, 2015
    Publication date: May 26, 2016
    Applicant: Katholieke Universiteit Leuven
    Inventors: Pau Sancho-Bru, Catherine M. Verfaillie
  • Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
    Patent number: 9090878
    Abstract: The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype and cells that express a hepatic sinusoidal endothelial phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other things, for treatment of liver deficiency, liver metabolism studies, and liver toxicity studies.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: July 28, 2015
    Assignee: Katholieke Universiteit Leuven
    Inventors: Pau Sancho-Bru, Catherine M. Verfaillie
  • Methods for Differentiating Cells into Hepatic Stellate Cells and Hepatic Sinusoidal Endothelial Cells, Cells Produced by the Methods, and Methods for Using the Cells
    Publication number: 20120009672
    Abstract: The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype and cells that express a hepatic sinusoidal endothelial phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other things, for treatment of liver deficiency, liver metabolism studies, and liver toxicity studies.
    Type: Application
    Filed: June 16, 2011
    Publication date: January 12, 2012
    Applicant: Katholieke Universitiet Leuven
    Inventors: Pau Sancho-Bru, Catherine M. Vefaillie