Patents by Inventor Paul A. Slesinger

Paul A. Slesinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kir channel modulators
    Patent number: 8097422
    Abstract: Provided is a three-dimensional structure of an alcohol bound to an alcohol-binding site of an inwardly rectifying potassium (Kir) channel, Kir channel alcohol modulators and methods for identifying Kir channel modulators.
    Type: Grant
    Filed: June 17, 2008
    Date of Patent: January 17, 2012
    Assignee: Salk Institute for Biological Studies
    Inventors: Scott D. Pegan, Paul A. Slesinger, Senyon Choe, Prafulla Aryal
  • KIR CHANNEL MODULATORS
    Publication number: 20090148861
    Abstract: Provided is a three-dimensional structure of an alcohol bound to an alcohol-binding site of an inwardly rectifying potassium (Kir) channel, Kir channel alcohol modulators and methods for identifying Kir channel modulators.
    Type: Application
    Filed: June 17, 2008
    Publication date: June 11, 2009
    Applicant: THE SALK INSTITUTE
    Inventors: Scott D. Pegan, Paul A. Slesinger, Senyon Choe, Prafulla Aryal
  • Mammalian inward rectifier potasssium channel cDNAs, host cells expressing them, and screening assays using such cells
    Patent number: 5670335
    Abstract: This disclosure relates to two separate and distinct inward rectifier K.sup.+ channel expression products and the the genes which encode each expression product. The IRK1 gene (SEQ ID NO:1) encodes an inward rectifier K.sup.+ channel and the GIRK1 gene (SEQ ID NO:3) encodes a G protein coupled muscarinic K.sup.+ channel. The disclosure relates to the uses of these expression products, particularly in combination with identifying physiological processes mediated by these channels, such as regulation of heartbeat and insulin release and materials modulating or blocking same.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 23, 1997
    Assignee: The Regents of the University of California
    Inventors: Lily Y. Jan, Yuh Nung Jan, Yoshihiro Kubo, Eithan Reuveny, Paul A. Slesinger