Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.

Abstract: The present invention relates to novel pyrimidine derivatives and their use in perfume compositions. The novel pyrimidine derivatives of the present invention are represented by the following formula: wherein m and n are integers that when m is 0, n is 1; when m is 1, n is 0 or 1; or when m is 2, n is 0; wherein (CH)m and (CH)n are each independently optionally substituted with a substituent selected from the group consisting of methyl and ethyl; wherein X is selected from the group consisting of N, O, and S; and wherein R1 and R2 each independently represent H or a hydrocarbon group, or R1 and R2 together represent a fused ring or a ring system, with the proviso that when R1 is H, R2 is not H.

Abstract: The present invention relates to novel quinazoline compounds and their use in perfume compositions. The novel quinazoline compounds of the present invention are represented by the following formula: an isomer or a mixture of isomers thereof, wherein the broken line represents a single or double bond.

Abstract: Radio Frequency (RF) signal conditioning circuitry, which includes RF detection circuitry and RF attenuation circuitry is disclosed. The RF detection circuitry receives and detects an RF sample signal to provide an RF detection signal. The RF attenuation circuitry has an attenuation circuitry input, and receives and attenuates the RF sample signal via the attenuation circuitry input to provide an attenuated RF signal. The RF attenuation circuitry presents an attenuation circuitry input impedance at the attenuation circuitry input. The attenuated RF signal and the RF detection signal are provided concurrently.

Abstract: In accordance with one or more aspects, a variable resolution image is displayed at an initial resolution. The variable resolution image has multiple portions, at least two of which have different resolutions. A request to display one of the multiple portions of the variable resolution image at a higher resolution is received, and a check is made as to whether a higher resolution version of the one portion is available. The higher resolution version of the one portion is displayed if available, otherwise the one portion at the initial resolution is displayed.

Abstract: Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.

Abstract: In accordance with one or more aspects, a variable resolution image is displayed at an initial resolution. The variable resolution image has multiple portions, at least two of which have different resolutions. A request to display one of the multiple portions of the variable resolution image at a higher resolution is received, and a check is made as to whether a higher resolution version of the one portion is available. The higher resolution version of the one portion is displayed if available, otherwise the one portion at the initial resolution is displayed.

Abstract: In accordance with one or more aspects, a variable resolution image is displayed at an initial resolution. The variable resolution image has multiple portions, at least two of which have different resolutions. A request to display one of the multiple portions of the variable resolution image at a higher resolution is received, and a check is made as to whether a higher resolution version of the one portion is available. The higher resolution version of the one portion is displayed if available, otherwise the one portion at the initial resolution is displayed.

Abstract: The present invention provides compounds that can inhibit the activity of soluble epoxide hydrolases. In particular, the present invention provides compounds of Formula I.

Abstract: In accordance with one or more aspects, multiple folders are generated each corresponding to one of multiple levels of an image pyramid, and each of the multiple levels including one or more tiles. In each of the multiple folders, one or more files are stored, each file including image data for a tile of the level corresponding to the folder. In accordance with other aspects, a first version of an image is generated, the first version of the image having a lower resolution than the image. The image is compressed using a first compression process, and the first version of the image is compressed using a second compression process, the second compression process being a higher quality process than the first compression process. Both the compressed image and the compressed first version of the image are stored as an image pyramid for the image.

Abstract: In accordance with one or more aspects, a variable resolution image is displayed at an initial resolution. The variable resolution image has multiple portions, at least two of which have different resolutions. A request to display one of the multiple portions of the variable resolution image at a higher resolution is received, and a check is made as to whether a higher resolution version of the one portion is available. The higher resolution version of the one portion is displayed if available, otherwise the one portion at the initial resolution is displayed.

Abstract: In accordance with one or more aspects, multiple folders are generated each corresponding to one of multiple levels of an image pyramid, and each of the multiple levels including one or more tiles. In each of the multiple folders, one or more files are stored, each file including image data for a tile of the level corresponding to the folder. In accordance with other aspects, a first version of an image is generated, the first version of the image having a lower resolution than the image. The image is compressed using a first compression process, and the first version of the image is compressed using a second compression process, the second compression process being a higher quality process than the first compression process. Both the compressed image and the compressed first version of the image are stored as an image pyramid for the image.

Abstract: An apparatus for storing and displaying a handicap parking permit as well as other parking tags on a vehicle. The apparatus comprises a holder member having each of a predetermined shape and a predetermined size and formed of a predetermined material. A pivoting clip member is engageable with a top portion of the holder member and there is a means for securing the pivoting clip member to a vehicle's sun visor.

Abstract: An earth-boring bit has a bit body and at least one cantilevered bearing shaft depending inwardly and downwardly from the bit body. A cutter is mounted for rotation on the bearing shaft and includes a plurality of cutting elements. At least one of the cutting elements has a generally cylindrical body formed of hard metal with a convex cutting end. A plurality of substantially recesses are formed on the cutting end of the body. The recesses are configured such that a line parallel to the longitudinal axis of the body may extend from any point of each of the recess without touching any other point on the same recess. This enables the cutting element body and the recess to be formed simultaneously by conventional powder metallurgical techniques. A layer of super-hard material is formed on the cutting end of the body and overlays the recesses formed thereon.

Abstract: A catalytically active aluminoxane can be synthesized from a precursor formed by the combination of at least one trialkylaluminum compound and at least one organoaluminum compound containing a carbon-oxygen bond therein, such as an alkoxy group-containing organoaluminum compound of the formula (CH.sub.3).sub.2 Al--O--R, where R is alkyl.

Abstract: Hydrocarbon solutions of a dialkylmagnesium compound having reduced viscosity contain: (a) a hydrocarbon solvent; (b) a dialkylmagnesium compound normally soluble in hydrocarbon solvents; and (c) an effective viscosity reducing amount of a compound selected from the group consisting of a compound having silicon-oxygen bonding, a compound having silicon-nitrogen bonding, and mixtures thereof. Representative viscosity reducing agents include: tetraalkylorthosilicate compounds, such as those of the general formula Si(OR).sub.4, where R is an alkyl group containing from 1 to about 4 carbon atoms, as exemplified by tetraethylorthosilicate; alkylsilazane compounds, including a hexaalkyldisilazane compound containing from 1 to about 4 carbon atoms in the alkyl groups therein as exemplified by hexamethyldisilazane; and silicone oil.

Abstract: An earth-boring bit has a bit body and at least one cantilevered bearing shaft depending inwardly and downwardly from the bit body. A cutter is mounted for rotation on the bearing shaft and includes a plurality of cutting elements. At least one of the cutting elements has a generally cylindrical body formed of hard metal with a convex cutting end. A plurality of substantially linear, parallel lands are formed on the cutting end of the body. The lands have arcuate top surfaces and define grooves between the land having arcuate bottom surfaces. A layer of super-hard material is formed on the cutting end of the body and engages the lands and grooves formed thereon.

Abstract: Partial vinyl-epoxy ester compositions are disclosed which can be cured by a dual path comprising exposure to UV radiation followed by a post thermal treatment. Simply, the partial esters contain from about 1 to 10 parts per hundred parts by weight of ester of a catalyst compound such as tertiary amines and imidazole compounds, salts and adducts thereof.

Abstract: A modified photocurable acrylate resin with improved adhesion to metals is prepared by reacting a liquid polyepoxide, an ethylenically unsaturated conjugated organic carboxylic acid, and a secondary monoamine.

Abstract: A modified photocurable acrylate resin with improved adhesion to metals is prepared by reacting a liquid polyepoxide, an ethylenically unsaturated conjugated organic carboxylic acid, and the half ester of an aliphatic monohydric alcohol and a polycarboxylic acid anhydride.