Patents by Inventor Paul David Schmitt

Paul David Schmitt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Characterization of trace crystallinity by second harmonic generation microscopy
    Patent number: 10309902
    Abstract: A method for quantifying crystallinity within a sample using second harmonic generation microscopy is described herein. In one aspect, a method for reducing the timeframe for accelerated stability testing of amorphous solid dispersions of active pharmaceutical ingredients though identifying regions of interest to quantify crystallinity and composition is presented herein.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: June 4, 2019
    Assignee: PURDUE RESEARCH FOUNDATION
    Inventors: Garth Jason Simpson, Paul David Schmitt
  • TRIBOLUMINESCENCE APPARATUS AND METHOD FOR RAPID DETECTION OF HOMOCHIRAL CRYSTALLINITY IN PHARMACEUTICAL FORMULATIONS
    Publication number: 20180313764
    Abstract: An impact-driven apparatus and method to achieve triboluminescence of homochiral API crystals as a measurement tool for rapidly assessing the presence of trace crystallinity within nominally amorphous pharmaceutical powders. The apparatus may include a kinetic energy director and two plates which hold a sample for testing. The triboluminescence may also be achieve by an acoustic transducer.
    Type: Application
    Filed: September 27, 2016
    Publication date: November 1, 2018
    Applicant: Purdue Research Foundation
    Inventors: Garth Jason Simpson, Paul David Schmitt, Scott Robert Griffin, Casey Jake Smith
  • CHARACTERIZATION OF TRACE CRYSTALLINITY BY SECOND HARMONIC GENERATION MICROSCOPY
    Publication number: 20170212053
    Abstract: A method for quantifying crystallinity within a sample using second harmonic generation microscopy is described herein. In one aspect, a method for reducing the timeframe for accelerated stability testing of amorphous solid dispersions of active pharmaceutical ingredients though identifying regions of interest to quantify crystallinity and composition is presented herein.
    Type: Application
    Filed: September 28, 2015
    Publication date: July 27, 2017
    Applicant: Purdue Research Foundation
    Inventors: Garth Jason Simpson, Paul David Schmitt