Patents by Inventor Paul-Ernst Frohberger

Paul-Ernst Frohberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4307020
    Abstract: 2-Carboxymethyl-3-carboxy-chromones and esters of the formula ##STR1## in which R, R.sup.1 and R.sup.2 each independently is hydrogen, an optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, aralkyl or aryl group, halogen, hydroxyl, cyano or an optionally substituted alkoxy aryloxy, aralkoxy, alkoxy-carbonyl or dialkylamino group, orR and R.sup.1, together with two carbon atoms of the benzene ring system, form a carbocyclic or heterocyclic 5-membered or 6-membered ring, andR.sup.3 is hydrogen, optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl or aralkyl,are characterized by fungicidal and arthropodicidal activities. The novel compounds are produced by reacting an o-hydroxyacetophenone of the formula ##STR2## with a glyoxylic acid derivative of the formulaOCH-COOZin which Z is a cation, in the presence of a basic compound, followed by acidification to form the dicarboxylic acid and, optionally, the ester.
    Type: Grant
    Filed: July 14, 1980
    Date of Patent: December 22, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Joachim Kabbe, Paul-Ernst Frohberger, Peter Roessler
  • Patent number: 4291044
    Abstract: 1-(Azol-1-yl)-2-substituted-alken-3-ones of the formula ##STR1## in which R.sup.1 represents alkyl, alkoxy, alkylthio, alkylsulphonyl, alkylcarbonyl, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylthio, optionally substituted phenylsulphonyl or optionally substituted phenyl carbonyl,R.sup.2 represents alkyl, cycloalkyl or optionally substituted phenyl andY represents a nitrogen atom or the CH group.
    Type: Grant
    Filed: October 12, 1979
    Date of Patent: September 22, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerhard Jager, Udo Kraatz, Karl H. Buchel, Paul-Ernst Frohberger, Wilhelm Brandes
  • Patent number: 4291047
    Abstract: .alpha.-Azolyl-.beta.-hydroxy-ketones of the formula ##STR1## in which R.sup.1 represents optionally substituted alkyl or optionally substituted phenyl,R.sup.2 represents the grouping --CX.sup.1 X.sup.2 R.sup.3 or alkoxycarbonyl,R.sup.3 represents halogen, halogenoalkyl or optionally substituted phenyl,X.sup.1 and X.sup.2, which may be identical or different, each represents hydrogen or halogen, andY represents a nitrogen atom or the CH group, or physiologically acceptable acid-addition salts or metal-salt complexes thereof which possess fungicidal properties.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: September 22, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Eckart Kranz, Wolfgang Kramer, Karl H. Buchel, Wilhelm Brandes, Paul-Ernst Frohberger
  • Patent number: 4285965
    Abstract: 2-Carboxymethyl-3-carboxy-chromones and esters of the formula ##STR1## in which R, R.sup.1 and R.sup.2 each independently is hydrogen, an optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, aralkyl or aryl group, halogen, hydroxyl, cyano or an optionally substituted alkoxy, aryloxy, aralkoxy, alkoxy-carbonyl or dialkylamino group, orR and R.sup.1, together with two carbon atoms of the benzene ring system, form a carbocyclic or heterocyclic 5-membered or 6-membered ring, andR.sup.3 is hydrogen, optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl or aralkyl,are characterized by fungicidal and arthropodicidal activities. The novel compounds are produced by reacting an o-hydroxyacetophenone of the formula ##STR2## with a glyoxylic acid derivative of the formulaOCH--COOZin whichZ is a cation,in the presence of a basic compound, followed by acidification to form the dicarboxylic acid and, optionally, the ester.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: August 25, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Joachim Kabbe, Paul-Ernst Frohberger, Peter Roessler
  • Patent number: 4284639
    Abstract: 1-Phenoxy-2-(2,4-dichlorophenyl)-1-(1,2,4-triazol-1-yl)-ethan-2-ones and -ols of the formula ##STR1## in which A is --C(O)-- or --CH(OH)--,X each independently is halogen, alkyl or optionally substituted phenyl, andn is 0, 1, 2 or 3,or a salt thereof, which possess fungicidal and antimicrobial properties rendering them useful in agriculture and pharmacy.
    Type: Grant
    Filed: February 28, 1980
    Date of Patent: August 18, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Wilhelm Brandes, Paul-Ernst Frohberger, Manfred Plempel
  • Patent number: 4264772
    Abstract: A 1-phenyl,1-oximino-2-(1,2,4-triazol-1-yl)-ethane of the formula ##STR1## in which R is halogen, alkyl, alkoxy, alkylthio, alkylsulphonyl, halogenoalkyl, nitro, cyano, optionally substituted phenyl or optionally substituted phenoxy,R' is alkyl, alkenyl, alkynyl, optionally substituted benzyl or optionally substituted styryl, andn is 0, 1, 2 or 3,or a salt thereof with a physiologically acceptable acid or a metal salt complex thereof which possesses fungicidal properties.
    Type: Grant
    Filed: March 22, 1979
    Date of Patent: April 28, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Helmut Timmler, Wilhelm Brandes, Paul-Ernst Frohberger
  • Patent number: 4262000
    Abstract: 3-Substituted pyridine derivatives of the formula ##STR1## in which A is --CO-- or --CH(OH)--,R is alkyl or optionally substituted phenyl,X each independently is halogen, alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl or optionally substituted phenylalkoxy,n is 0, 1, 2 or 3, andm is 0 or 1,or a physiologically acceptable acid addition salt or metal salt complex thereof, which possess fungicidal activity.
    Type: Grant
    Filed: February 15, 1980
    Date of Patent: April 14, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Graham Holmwood, Paul-Ernst Frohberger
  • Patent number: 4255434
    Abstract: Fungicidal 1-(azol-1-yl)-4-halo-1-phenoxy-butan-2-ones and -ols of the formula ##STR1## in which R represents alkyl with 1 to 4 carbon atoms;X represents hydrogen, alkyl with 1 to 4 carbon atoms or halogen;Y represents halogen;Z represents halogen, straignt-chain or branched alkyl with 1 to 4 carbon atoms, cycloalkyl with 5 to 7 carbon atoms, halogenoalkyl with 1 or 2 carbon atoms and 1 to 5 halogen atoms, alkoxy with one or 2 carbon atoms, alkylthio with 1 or 2 carbon atoms, alkoxycarbonyl with 1 to 5 carbon atoms in the alkoxy part, amino, cyano, nitro, phenyl or phenoxy substituted with at least one of halogen, amino, cyano, nitro and alkyl with 1 to 2 carbon atoms, phenylalkyl with 1 or 2 carbon atoms on the alkyl part optionally substituted in the alkyl part by alkylcarbonyl with a total of up to 3 carbon atoms and in the phenyl part by halogen, nitro or cyano;n represents 0,1,2 or 3,A is --CO-- or CH(OH)--, andB is --N.dbd. or --CH.dbd., or a salt thereof.
    Type: Grant
    Filed: November 27, 1978
    Date of Patent: March 10, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl Buchel, Paul-Ernst Frohberger, Wilhelm Brandes, Hans Scheinpflug
  • Patent number: 4254132
    Abstract: A 2-acyloxy-1-azolyl-3,3-dimethyl-2-phenoxy-butane of the formula ##STR1## in which A represents a nitrogen atom or the CH group,R represents alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, cycloalkyl, halogenoalkyl, optionally substituted phenyl, optionally substituted phenylalkyl, optionally substituted phenoxyalkyl, alkylamino, dialkylamino, optionally substituted phenylamino, halogenalkylamino, alkoxycarbonylamino, or alkoxyalkylamino,X represents hydrogen, halogen or alkylcarbonyloxy,Y represents halogen or alkylcarbonyloxy,Z represents halogen, alkyl, cycloalkyl, alkoxy, halogenoalkyl, alkylthio, alkoxycarbonyl, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl, cyano or nitro, andn represents 0, 1, 2, 3, 4 or 5, the substituents Z being selected independently of one another when n is 2 or more,and salts and complexes thereof which possess fungicidal properties.
    Type: Grant
    Filed: February 22, 1979
    Date of Patent: March 3, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Paul-Ernst Frohberger, Wilhelm Brandes
  • Patent number: 4251512
    Abstract: Synergistic fungicidal compositions comprising ##STR1## in which R.sup.1 is optionally substituted phenyl,R.sup.2 is hydrogen, alkyl or phenyl,R.sup.3 is alkyl, cycloalkyl, phenyl or chlorophenyl, andY is a keto group or a functional derivative thereof,and at least one member selected from the group consisting of(a) dithiocarbamates,(b) N-polyhaloalkylthio-amines or -amides,(c) imidazole and benzimidazole derivatives,(d) optionally nitrated polyhalobenzenes,(e) N-sulphinyl-N'-aryl-hydrazines, and(f) sulphur or alkaline earth metal polysulphides.
    Type: Grant
    Filed: November 15, 1976
    Date of Patent: February 17, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wilhelm Brandes, Paul-Ernst Frohberger, Hans Scheinpflug, Wolfgang Kramer
  • Patent number: 4246276
    Abstract: 2,2-Difluoro-5-(2,4-dinitro-6-trifluoromethylphenylamino)-benzodioxoles of the formula ##STR1## in which R is hydrogen, halogen or alkyl optionally substituted by halogen,which possess arthropodicidal, microbicidal and herbicidal properties.
    Type: Grant
    Filed: May 16, 1979
    Date of Patent: January 20, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Alfons Hartmann, Albrecht Marhold, Reinhard Lantzsch, Ingeborg Hammann, Paul-Ernst Frohberger, Wilhelm Brandes
  • Patent number: 4239766
    Abstract: A 1-(4-phenoxy)-3,3-dimethyl-2-(N-halogenoalkylmercapto-carbamoyloxy)-1-(1,2 ,4-triazol-1-yl)-butane of the formula ##STR1## in which R.sup.1 is alkyl or optionally substituted phenyl,R.sup.2 is halogenoalkyl,X is hydrogen or halogen,Y is hydrogen or halogen,Z each independently is alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, alkoxycarbonyl, optionally substituted phenyl, phenoxy or phenylalkyl, cyano or nitro, andn is 0, 1, 2, 3, 4 or 5,and physiologically acceptable acid addition salts and metal salt complexes thereof which possess fungicidal properties.
    Type: Grant
    Filed: June 7, 1979
    Date of Patent: December 16, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Engelbert Kuhle, Paul-Ernst Frohberger, Wilhelm Beandes
  • Patent number: 4239760
    Abstract: 3-Azolyl-benzo-1,2,4-triazines or 1-oxides thereof of the formula ##STR1## in which X represents halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylmercapto, C.sub.1 -C.sub.4 alkylsulphonyl, nitro or trifluoromethyl,m represents 0, 1, 2, 3 or 4, the substituents X being selected independently of one another when m is 2 or more,n represents 0 or 1 andAz represents a five-membered hetero-aromatic ring with 2 or 3 nitrogen atoms, which is bonded via nitrogen and which can be optionally substituted, which possess fungicidal and bactericidal properties.
    Type: Grant
    Filed: January 8, 1979
    Date of Patent: December 16, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Sasse, Walter Gauss, Paul-Ernst Frohberger, Peter Kraus, Volker Paul
  • Patent number: 4237143
    Abstract: 2-Methylene-3-substituted-4,5-bis-trifluoromethylimino-thiazoldines of the formula ##STR1## in which R.sup.1 represents optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted aryl, aralkyl, it being possible for the last-mentioned group to be substituted on the alkyl radical, or an amino group --NR.sup.4 R.sup.5, whereinR.sup.4 and R.sup.5 may be identical or different, each represent optionally substituted alkyl, or R.sup.4 and R.sup.5 together with the connecting nitrogen atom and optionally one or more further heteroatoms, form a 4-membered to 12-membered heterocyclic ring,R.sup.2 represents cyano, alkoxycarbonyl, acyl, alkylsulphonyl or arylspulphonyl, the four last-mentioned groups being optionally substituted, or represents an amide or thioamide group, comprising the radical CO--NR.sup.6 R.sup.7 or CS--NR.sup.6 R.sup.7, whereinR.sup.6 represents hydrogen or alkyl andR.sup.
    Type: Grant
    Filed: February 5, 1979
    Date of Patent: December 2, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Grohe, Hans-Joachim Scholl, Volker Paul, Wilhelm Brandes, Paul-Ernst Frohberger
  • Patent number: 4234587
    Abstract: N,N-Dimethyl-carbamic acid O-(2-substituted-methyl-pyrimidin-4-yl)-esters of the formula ##STR1## in which R is alkyl,R.sup.1 is hydrogen or alkyl,R.sup.2 is hydrogen, alkyl or halogen, orR.sup.1 and R.sup.2 together are alkanediyl, andn is 1 or 2,which possess arthropodicidal and fungicidal properties.
    Type: Grant
    Filed: August 22, 1979
    Date of Patent: November 18, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Fritz Maurer, Rolf Schroder, Ingeborg Hammann, Bernhard Homeyer, Paul-Ernst Frohberger
  • Patent number: 4232033
    Abstract: Substantially pure diastereomeric form A of 1-phenoxy-3,3-dimethyl-1-(1,2,4-triazol-1-yl)-butan-2-ols of the formula ##STR1## in which X represents halogen, optionally substituted p- or m-phenyl, substituted o-phenyl, alkyl, alkoxycarbonyl or nitro, andn represents an integer from 1 to 5,which possess fungicidal properties.
    Type: Grant
    Filed: September 11, 1978
    Date of Patent: November 4, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Wolf-Dietrich Pflugbeil, Paul-Ernst Frohberger, Wilhelm Brandes
  • Patent number: 4229459
    Abstract: Azolyl ether derivatives of the formula ##STR1## in which A is CH or a nitrogen atom,R is alkyl, alkenyl, alkynyl, phenyl, benzyl or substituted phenyl or benzyl,X is halogen, alkyl, alkoxy, alkylthio, alkylsulphonyl, halogenoalkyl, alkoxycarbonyl, nitro, cyano, phenyl, phenoxy, phenylthio, or substituted phenyl, phenoxy of phenylthio,Y is alkyl, phenyl, or substituted alkyl or phenyl andn is 0, 1, 2, 3, 4 or 5,which possess fungicidal properties.
    Type: Grant
    Filed: April 26, 1978
    Date of Patent: October 21, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Wilhelm Brandes, Paul-Ernst Frohberger, Volker Paul
  • Patent number: 4228178
    Abstract: N-Sulphenylated carbamoyl compounds of the formula ##STR1## in which Z represents two adjacent C atoms of a bifunctional lower aliphatic radical, of a cycloaliphatic radical or of an optionally substituted aromatic radical,m denotes the number 0 or 1 andn denotes the number 0, 1, 2 or 3,which possess fungicidal properties.
    Type: Grant
    Filed: November 13, 1978
    Date of Patent: October 14, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Engelbert Kuhle, Wilhelm Brandes, Paul-Ernst Frohberger
  • Patent number: 4207328
    Abstract: This invention relates to new 2,4-dichlorophenyl-imidaziolyl-ethan-ones and -ols useful as antimycotic and fungicidal agents. The compounds are useful as medicaments as well as in the plant protection area.
    Type: Grant
    Filed: January 27, 1978
    Date of Patent: June 10, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Karl H. Buchel, Manfred Plempel, Wilhelm Brandes, Paul-Ernst Frohberger
  • Patent number: 4189498
    Abstract: 2-Carboxymethyl-3-carboxy-chromones and esters of the formula ##STR1## in which R, R.sup.1 and R.sup.2 each independently is hydrogen, an optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, aralkyl or aryl group, halogen, hydroxyl, cyano or an optionally substituted alkoxy, aryloxy, aralkoxy, alkoxy-carbonyl or dialkylamino group, orR and R.sup.1, together with two carbon atoms of the benzene ring system, form a carbocyclic or heterocyclic 5-membered or 6-membered ring, andR.sup.3 is hydrogen, optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl or aralkyl,are characterized by fungicidal and arthropodicidal activities. The novel compounds are produced by reacting an o-hydroxyacetophenone of the formula ##STR2## with a glyoxylic acid derivative of the formulaOCH--COOZin whichZ is a cation,in the presence of a basic compound, followed by acidification to form the dicarboxylic acid and, optionally, the ester.
    Type: Grant
    Filed: June 22, 1978
    Date of Patent: February 19, 1980
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Joachim Kabbe, Paul-Ernst Frohberger, Peter Roessler