Patents by Inventor Paul Frederik Gründeman
Paul Frederik Gründeman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11376123Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet attached to a supporting element, which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets.Type: GrantFiled: December 3, 2019Date of Patent: July 5, 2022Assignee: DSM IP ASSETS B.V.Inventors: Paul Frederik Gründeman, Jolanda Kluin, Karlien Kristal Boon-Ceelen, Thomas König
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Publication number: 20200107928Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet attached to a supporting element, which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets.Type: ApplicationFiled: December 3, 2019Publication date: April 9, 2020Inventors: Paul Frederik GRÜNDEMAN, Jolanda KLUIN, Karlien Kristal BOON-CEELEN, Thomas KÖNIG
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Patent number: 10524902Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet (3) attached to a supporting element (2), which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface (700) to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets. The invention also relates to a leaflet assembly for use in a prosthetic valve, and to methods of making the prosthetic valve, including making the leaflet assembly.Type: GrantFiled: December 28, 2017Date of Patent: January 7, 2020Assignee: DSM IP ASSETS B.V.Inventors: Paul Frederik Gründeman, Jolanda Kluin, Karlien Kristal Boon-Ceelen, Thomas König
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Patent number: 10098992Abstract: Heart support device for circulatory assistance, with an internal member (6) to be disposed inside a heart lumen (13) and having a dynamic volume body. The internal member (6) has a substantially stiff wall strengthening portion (8) arranged to engage an inner wall surface (12a) of the heart (10) in operation and a dynamic member (9) that is inflatable to assist pumping action of the heart (10).Type: GrantFiled: June 30, 2015Date of Patent: October 16, 2018Assignee: Stichting Katholieke UniversiteitInventors: Daniël Immanuel Michaël van Dort, Harry Suryapranata, Paul Frederik Gründeman, Jakob Roelf Lahpor
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Patent number: 10070855Abstract: A surgical device (5) for application in a treatment performed on the human or animal body (1) with the aim of providing access to a surgical site in the body, includes at least one inflatable chamber (70, 71, 72) which can be inflated from a collapsed state to an expanded state, in which expanded state the device is suitable for exerting a force on an organ or tissue at the surgical site, at least one elongated flexible member (8, 80), which member at its proximal end (801) is operatively connected to the device, and which member has a length to allow the distal end (800) of the member to be fixed to a fixation site (100, 101) outside of the body, and methods of using this device.Type: GrantFiled: June 12, 2014Date of Patent: September 11, 2018Assignee: UMC UTRECHT HOLDING B.V.Inventors: Paul Frederik Gründeman, Paul Barteld Kwant
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Publication number: 20180193137Abstract: Prosthetic valves are provided with a leaflet assembly having at least one leaflet (3) attached to a supporting element (2), which leaflet has a free margin that can move between a first position wherein the free margin is flexed away from a closure surface (700) to allow body fluid to flow through the valve, and a second position wherein the free margin abuts the closure surface to close the valve, and wherein the leaflet, without pulsatile load on the valve, can form a coaptation height H of more than 0.1 mm along the length of the free margin. Such prosthetic valve provides good performance during prolonged time, and can be made using various materials for the leaflets. The invention also relates to a leaflet assembly for use in a prosthetic valve, and to methods of making the prosthetic valve, including making the leaflet assembly.Type: ApplicationFiled: December 28, 2017Publication date: July 12, 2018Inventors: Paul Frederik GRÜNDEMAN, Jolanda KLUIN, Karlien Kristal BOON-CEELEN, Thomas KÖNIG
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Publication number: 20170136162Abstract: Heart support device for circulatory assistance, with an internal member (6) to be disposed inside a heart lumen (13) and having a dynamic volume body. The internal member (6) has a substantially stiff wall strengthening portion (8) arranged to engage an inner wall surface (12a) of the heart (10) in operation and a dynamic member (9) that is inflatable to assist pumping action of the heart (10).Type: ApplicationFiled: June 30, 2015Publication date: May 18, 2017Applicant: STICHTING KATHOLIEKE UNIVERSITEITInventors: Daniël Immanuel Michaël van Dort, Harry Suryapranata, Paul Frederik Gründeman, Jakob Roelf Lahpor
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Publication number: 20160120531Abstract: A surgical device (5) for application in a treatment performed on the human or animal body (1) with the aim of providing access to a surgical site in the body, includes at least one inflatable chamber (70, 71, 72) which can be inflated from a collapsed state to an expanded state, in which expanded state the device is suitable for exerting a force on an organ or tissue at the surgical site, at least one elongated flexible member (8, 80), which member at its proximal end (801) is operatively connected to the device, and which member has a length to allow the distal end (800) of the member to be fixed to a fixation site (100, 101) outside of the body, and methods of using this device.Type: ApplicationFiled: June 12, 2014Publication date: May 5, 2016Inventors: Paul Frederik GRÜNDEMAN, Paul Barteld KWANT
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Patent number: 8764646Abstract: A surgical device for application in a treatment performed on the human or animal body with the aim of providing access to a surgical site in the body by exerting a force, upon expansion of the device at the location of the surgical site, on the organs and/or tissues at the surgical site, e.g. for mobilizing and/or supporting organs and/or tissues, the surgical device including an expansion structure, at least one fluid reservoir, and a conduit for conveying fluid from the reservoir to the expansion structure.Type: GrantFiled: April 29, 2004Date of Patent: July 1, 2014Assignee: UMC Utrecht Holding B.V.Inventor: Paul Frederik Gründeman
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Patent number: 6790171Abstract: Invention relates to a cannula and a screw pump for use in a mechanical circulatory support device, in particular a transventricular circulatory support device. The cannula according to the present invention comprises a tubular member made of a flexible, collapsible material having a diameter between 0.5 cm and 3 cm, preferably between 1 cm and 2.5 cm. The invention also relates to an inflatable screw pump for use in circulatory support system which comprises a flexible central drive shaft and an inflatable body having a free edge defining a spiral shaped contour around the central drive shaft and an inner edge connected to the drive shaft. The Archimedes type screw pump may be used in conjunction with the flexible cannula.Type: GrantFiled: March 1, 2002Date of Patent: September 14, 2004Assignee: Universitair Medisch Cenrum UtrechtInventors: Paul Frederik Gründeman, Cornelis Wilhelmus Jozef Verlaan, Cornelius Borst, Hendricus Jacobus Mansvelt Beck