Patents by Inventor Paul Gokhale

Paul Gokhale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of cell phenotype by inhibitory rna
    Publication number: 20070093435
    Abstract: We describe a method to inhibit cell division of hyperproliferative cells, typically cancer cells, by introducing inhibitory RNA (RNAi) into said cells to ablate mRNAs that encode polypeptides involved in cellular processes and including RNAi molecules and vectors including transcription cassettes encoding said RNAi molecules. By application of said RNAi molecules to cancers in vivo it is possible to effect a treatment whereby the cancer cells are killed or otherwise eliminated.
    Type: Application
    Filed: March 25, 2004
    Publication date: April 26, 2007
    Inventors: Peter Andrews, Paul Gokhale, Jim Walsh, Maryam Matin
  • Pluripotential stem cells
    Publication number: 20070087991
    Abstract: We describe a method to manipulate the phenotype of stem cells, preferably pluripotential stem cells including nucleic acids and vectors used in said methods.
    Type: Application
    Filed: November 16, 2006
    Publication date: April 19, 2007
    Applicant: AXORDIA LIMITED
    Inventors: Peter Andrews, James Walsh, Paul Gokhale
  • Pluripotential stem cells
    Publication number: 20050202428
    Abstract: We describe a method to manipulate the phenotype of stem cells, preferably pluripotential stem cells including nucleic acids and vectors used in said methods.
    Type: Application
    Filed: February 12, 2003
    Publication date: September 15, 2005
    Applicant: AXORDIA LIMITED
    Inventors: Peter Andrews, James Walsh, Paul Gokhale
  • Stem cell
    Publication number: 20040171153
    Abstract: There is provided a method to modulate the differentiation state of embryonic stem cells in culture by the providing ligands which bind receptors in the Notch and Wnt pathways.
    Type: Application
    Filed: March 25, 2004
    Publication date: September 2, 2004
    Inventors: Peter Andrews, James Walsh, Paul Gokhale
  • Stem cell differentiation
    Publication number: 20040053869
    Abstract: The invention relates to a method to modulate stem cell differentiation comprising introducing inhibitory RNA (RNAi) into a stem cell to ablate mRNA's which encode polypeptides which are involved in stem cell differentiation; RNAi molecules, DNA molecules encoding said RNAi molecules; and cells obtained by said method.
    Type: Application
    Filed: August 5, 2003
    Publication date: March 18, 2004
    Inventors: Peter Andrews, James Walsh, Paul Gokhale