Patents by Inventor Paul Gregor Sappler

Paul Gregor Sappler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic human genes and polypeptides and their use in the treatment of autoimmune diseases
    Patent number: 8501189
    Abstract: Synthetic human target autoantigen genes comprising sequences coding for at least two immunogenic epitopic clusters (hereinafter IEC) of autoantigen(s) related to a specific autoimmune disease, wherein said at least two IECs may be derived from a sole autoantigen or from at least two different autoantigens related to said autoimmune disease, and polypeptides encoded thereby, can be used for the treatment and the diagnosis of autoimmune diseases such as multiple sclerosis (MS), insulin-dependent diabetes mellitus (IDDM), rheumatoid arthritis (RA), myasthenia gravis (MG) and uveitis.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: August 6, 2013
    Inventors: Avraham Ben-Nun, Nicole Kerlero De Rosbo, Paul Gregor Sappler
  • SYNTHETIC HUMAN GENES AND POLYPEPTIDES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES
    Publication number: 20120172297
    Abstract: Synthetic human target autoantigen genes comprising sequences coding for at least two immunogenic epitopic clusters (hereinafter IEC) of autoantigen(s) related to a specific autoimmune disease, wherein said at least two IECs may be derived from a sole autoantigen or from at least two different autoantigens related to said autoimmune disease, and polypeptides encoded thereby, can be used for the treatment and the diagnosis of autoimmune diseases such as multiple sclerosis (MS), insulin-dependent diabetes mellitus (IDDM), rheumatoid arthritis (RA), myasthenia gravis (MG) and uveitis.
    Type: Application
    Filed: December 29, 2011
    Publication date: July 5, 2012
    Inventors: AVRAHAM BEN-NUN, NICOLE KERLERO DE ROSBO, PAUL GREGOR SAPPLER
  • Synthetic human genes and polypeptides and their use in the treatment of autoimmune diseases
    Patent number: 8088389
    Abstract: Synthetic human target autoantigen genes comprising sequences coding for at least two immunogenic epitopic clusters (hereinafter IEC) of autoantigen(s) related to a specific autoimmune disease, wherein said at least two IECs may be derived from a sole autoantigen or from at least two different autoantigens related to said autoimmune disease, and polypeptides encoded thereby, can be used for the treatment and the diagnosis of autoimmune diseases such as multiple sclerosis (MS), insulin-dependent diabetes mellitus (IDDM), rheumatoid arthritis (RA), myasthenia gravis (MG) and uveitis.
    Type: Grant
    Filed: October 26, 2000
    Date of Patent: January 3, 2012
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Avraham Ben-Nun, Nicole Kerlero De Rosbo, Paul Gregor Sappler