Abstract: Wellbore synthesis techniques are disclosed suitable for use in geothermal applications. Embodiments are provided where open hole drilled wellbores are sealed while drilling to form an impervious layer at the wellbore/formation interface. The techniques may be chemical, thermal, mechanical, biological and are fully intended to irreversibly damage the formation in terms of the permeability thereof. With the permeability negated, the wellbore may be used to create a closed loop surface to surface geothermal well operable in the absence of well casing for maximizing thermal transfer to a circulating working fluid. Formulations for the working and drilling fluids are disclosed.

Abstract: Closed loop wellbore configurations with unrestricted geometry for accommodating irregular or challenging thermal gradients within a thermally productive formation are disclosed. A working fluid is utilized in the loop for extraction of thermal energy there from. The loop and the unrestricted geometry are achieved using magnetic ranging of independent drilling operations which intersect from an inlet well and outlet well to form an interconnecting segment. In conjunction with the directional drilling, conditioning operations are incorporated to condition the rock face, cool the entire system, activate the wellbore for treatment to optimize thermal transfer inter alia. The significant degree of freedom in wellbore configuration is further optimized by the absence of mechanical impediments such as casing or liners in the heat transfer areas.

Abstract: The present disclosure generally relates to a method for preparing a powder or granular foam control compositions and methods for reducing or preventing or breaking foam in various applications such as powder detergents as well as coatings, cementing, concrete, gypsum board and other construction type applications or in some agricultural formulations like fertilizers, herbicides and pesticides.

Abstract: A visual perception device is described. The visual perception device has corrective optics for viewing virtual and real-world content. An insert for the corrective optics is attached using a magnetic set, pins and/or a nose piece. Interchangeable nose pieces allow for height adjustments to accommodate different users. The visual perception device has pliable components to absorb forces exerted on a nose piece and a protective barrier for limiting electric shock or ingress of dirt.

Abstract: A visual perception device is described. The visual perception device has corrective optics for viewing virtual and real-world content. An insert for the corrective optics is attached using a magnetic set, pins and/or a nose piece. Interchangeable nose pieces allow for height adjustments to accommodate different users. The visual perception device has pliable components to absorb forces exerted on a nose piece and a protective barrier for limiting electric shock or ingress of dirt.

Abstract: Methods of assessing, such as characterizing or determining, condensate-associated characteristics of a compound, such as a test compound, and applications thereof are provided. For example, methods of determining a partition characteristic of a test compound in a target condensate, methods of determining a relative partition characteristic of a test compound in a target condensate, and methods of determining a condensate preference profile of a test compound are provided. Additionally, methods of designing and/or identifying and/or making a compound, or portion thereof, with a desired relative condensate partition characteristic are provided.

Abstract: Methods of identifying a compound, such as a test compound, and applications thereof are provided. For example, methods of identifying a compound that preferentially affects, increases, or decreases a level of association of a macromolecule with one or more target condensates or methods of identifying a compound that preferentially causes a macromolecule to associate or disassociate with one or more target condensates are provided. Additionally, methods of designing and/or identifying and/or making a compound, or portion thereof, with a desired characteristic are provided.

Abstract: The present disclosure, in some aspects, is directed to methods for screening and identifying compounds that modulate one or more characteristics associated with a condensate comprising a RBM20 polypeptide and/or the RBM20 polypeptide. In other aspects, the disclosure is directed to systems and composition components thereof, such as cellular models useful for the methods described herein.

Abstract: An egg incubator includes a base assembly having a base tray configured to support a plurality of eggs and a motorized egg turner configured to turn the plurality of eggs. The egg turner includes a hub, a first ring concentric with the hub, and a first plurality of spokes extending radially from the hub. Each of the first plurality of spokes is circumferentially-spaced from an adjacent spoke of the first plurality of spokes and includes: a radial member extending from the hub toward the first ring, a first diverging member extending obliquely from the radial member to the first ring, and a second diverging member extending obliquely from the radial member to the first ring. The motorized egg turner also includes a second ring positioned outward from and circumscribing the first ring and a second plurality of spokes extending radially between the inner ring and the outer ring.

Abstract: Methods of assessing, such as characterizing or determining, condensate-associated characteristics of a compound, such as a test compound, and applications thereof are provided. For example, methods of determining a partition characteristic of a test compound in a target condensate, methods of determining a relative partition characteristic of a test compound in a target condensate, and methods of determining a condensate preference profile of a test compound are provided. Additionally, methods of designing and/or identifying and/or making a compound, or portion thereof, with a desired relative condensate partition characteristic are provided.

Abstract: Methods of identifying a compound, such as a test compound, and applications thereof are provided. For example, methods of identifying a compound that preferentially affects, increases, or decreases a level of association of a macromolecule with one or more target condensates or methods of identifying a compound that preferentially causes a macromolecule to associate or disassociate with one or more target condensates are provided. Additionally, methods of designing and/or identifying and/or making a compound, or portion thereof, with a desired characteristic are provided.

Abstract: A visual perception device is described. The visual perception device has corrective optics for viewing virtual and real-world content. An insert for the corrective optics is attached using a magnetic set, pins and/or a nose piece. Interchangeable nose pieces allow for height adjustments to accommodate different users. The visual perception device has pliable components to absorb forces exerted on a nose piece and a protective barrier for limiting electric shock or ingress of dirt.

Abstract: A visual perception device is described. The visual perception device has corrective optics for viewing virtual and real-world content. An insert for the corrective optics is attached using a magnetic set, pins and/or a nose piece. Interchangeable nose pieces allow for height adjustments to accommodate different users. The visual perception device has pliable components to absorb forces exerted on a nose piece and a protective barrier for limiting electric shock or ingress of dirt.

Abstract: Methods of identifying a compound, such as a test compound, and applications thereof are provided. For example, methods of identifying a compound that preferentially affects, increases, or decreases a level of association of a macromolecule with one or more target condensates or methods of identifying a compound that preferentially causes a macromolecule to associate or disassociate with one or more target condensates are provided. Additionally, methods of designing and/or identifying and/or making a compound, or portion thereof, with a desired characteristic are provided.

Abstract: An egg incubator includes a base assembly having a base tray configured to support a plurality of eggs and a motorized egg turner configured to turn the plurality of eggs. The egg turner includes a hub, a first ring concentric with the hub, and a first plurality of spokes extending radially from the hub. Each of the first plurality of spokes is circumferentially-spaced from an adjacent spoke of the first plurality of spokes and includes: a radial member extending from the hub toward the first ring, a first diverging member extending obliquely from the radial member to the first ring, and a second diverging member extending obliquely from the radial member to the first ring. The motorized egg turner also includes a second ring positioned outward from and circumscribing the first ring and a second plurality of spokes extending radially between the inner ring and the outer ring.

Abstract: An egg incubator having a base assembly, a window, and a lid assembly. The base assembly includes a base tray configured to support a plurality of eggs, and a first water trough beneath the base tray and configured to retain a quantity of water. The window is removably coupled to the base assembly. The lid assembly is coupled to the window. The base assembly, window, and the lid assembly enclose a main incubation chamber sized to hold a plurality of eggs therein. The lid assembly includes a heating element configured to heat the main incubation chamber to a desired temperature, and a circulating fan configured to generate an airflow over the heating element.

Abstract: An egg incubator having a base assembly, a window, and a lid assembly. The base assembly including a base tray configured to support a plurality of eggs, a water trough beneath the base tray and configured to retain a quantity of water, and a motorized egg turner configured to periodically turn the plurality of eggs. The window is configured to be removably coupled to the base assembly. The lid assembly is coupled to the window. The base assembly, window, and the lid assembly enclose a main incubation chamber sized to hold a plurality of eggs therein. The lid assembly includes a heating element configured to heat the main incubation chamber to a desired temperature, and a circulating fan configured to generate an airflow over the heating element.