Abstract: The present invention relates to a combination of elafibranor with either riboflavin or DHA as antiviral agent. The bacteriophage T4 titer on E. coli that is increased by elafibranor in comparison to an untreated control is reversed by the combination of elafibranor with riboflavin or elafibranor with DHA. Therefore, these combinations decrease adverse side effects of elafibranor on the gut microbiota.

Abstract: The present invention relates to systemic detoxification and chronic inflammation by using extract fractions of Laurus nobilis, that lead to a decrease of anti-inflammatory markers in human lung cell lines and the activation of the Nrf2 pathway, which is a crucial element in intracellular detoxification pathways, decreases the expression of inflammatory cytokines. Therefore, the extract can be used to reduce the adverse effects of air pollution generally (and especially of particulate air pollution), which includes: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues that come into contact with air borne particles.

Abstract: The present invention relates to systemic detoxification by using extracts of Withania somnifera (ashwagandha) and its Nrf2-activating components withaferin-A, 12-deoxywithastramonolide, and Quresimine A. When ingested, the transcription factor Nrf2, which is a crucial element in intracellular detoxification pathways, leads to elimination of potentially toxic compounds. In parallel, the expression of inflammatory cytokines is decreased. Therefore, the extract can be used to reduce the adverse effects of air pollution generally (and especially of particulate air pollution), which includes: cardiovascular problems, respiratory diseases, and chronic inflammation of tissues that come into contact with air borne particles.

Abstract: When performing nuclear (e.g., SPECT or PET) and CT scans on a patient, a volume cone-beam CT scan is performed using a cone-beam CT X-ray source (20) and an offset flat panel X-ray detector (22). A field of view of the X-ray source overlaps a field of view of two nuclear detector heads (18), and the offset of the X-ray detector (22) minimizes interference with nuclear detector head movement about a rotatable gantry (16). Additionally, a locking mechanism (80) provides automatically locking of the X-ray detector (22) in each of a stowed and operation position, improving safety and CT image quality.

Abstract: When performing nuclear (e.g., SPECT or PET) and CT scans on a patient, a volume cone-beam CT scan is performed using a cone-beam CT X-ray source (20) and an offset flat panel X-ray detector (22). A field of view of the X-ray source overlaps a field of view of two nuclear detector heads (18), and the offset of the X-ray detector (22) minimizes interference with nuclear detector head movement about a rotatable gantry (16). Additionally, a locking mechanism (80) provides automatically locking of the X-ray detector (22) in each of a stowed and operation position, improving safety and CT image quality.

Abstract: A power supply system for supplying electrical power to at least one load includes a base plate, a support rail and a power supply module fastened to the base plate, at least one bus bar module, and a rail mounting device for mounting the bus bar module on the support rail. The rail mounting device includes conductor members for supplying power from the power supply module to bus bars contained within the bus bar modules, respectively. A first plug has contacts that engage contacts of each of the bus bars of the bus bar module via access slots contained in the cover member thereof, thereby to supply three-phase power to a load such, as a motor, via a heavy-duty power switch and a circuit breaker that are both mounted on the base plate, and associated second and third connecting plugs. Single-phase power is supplied to an auxiliary load, such as an electrical appliance, from two or more bus bars of the bus bar module via a fourth plug.

Abstract: A telescopic table system (32) is used for imaging a subject in at least a first modality (12) and a second modality (14). The first modality is disposed adjacent to the second modality to align a subject receiving bore (24) of the first modality with a subject receiving bore (36) of the second modality. The telescoping table system (32) includes a base (108), an intermediate pallet (78) and a subject pallet (82) on which a subject is loaded prior to imaging. The subject pallet (82) is mounted and supported to retain a constant cantilevering with respect to the intermediate pallet (78) at all longitude positions to prevent deflection changes while extending into any of the imaging modalities. The subject pallet (82) is moved through the first modality subject receiving bore (24) for imaging in the first modality. The subject pallet (82) is withdrawn from the first modality (12) and aligned with the intermediate pallet (78).

Abstract: A telescopic table system (32) is used for imaging a subject in at least a first modality (12) and a second modality (14). The first modality is disposed adjacent to the second modality to align a subject receiving bore (24) of the first modality with a subject receiving bore (36) of the second modality. The telescoping table system (32) includes a base (108), an intermediate pallet (78) and a subject pallet (82) on which a subject is loaded prior to imaging. The subject pallet (82) is mounted and supported to retain a constant cantilevering with respect to the intermediate pallet (78) at all longitude positions to prevent deflection changes while extending into any of the imaging modalities. The subject pallet (82) is moved through the first modality subject receiving bore (24) for imaging in the first modality. The subject pallet (82) is withdrawn from the first modality (12) and aligned with the intermediate pallet (78).

Abstract: A power supply system for supplying electrical power to at least one load includes a base plate, a support rail and a power supply module fastened to the base plate, at least one bus bar module, and a rail mounting device for mounting the bus bar module on the support rail. The rail mounting device includes conductor members for supplying power from the power supply module to bus bars contained within the bus bar modules, respectively. A first plug has contacts that engage contacts of each of the bus bars of the bus bar module via access slots contained in the cover member thereof, thereby to supply three-phase power to a load such, as a motor, via a heavy-duty power switch and a circuit breaker that are both mounted on the base plate, and associated second and third connecting plugs. Single-phase power is supplied to an auxiliary load, such as an electrical appliance, from two or more bus bars of the bus bar module via a fourth plug.

Abstract: A system for exchanging and storing collimators for medical imaging devices includes a first frame having a first receptacle and a second frame having a first docking member. A collimator can be attached to and removed from the first receptacle. The first docking member can be positioned adjacent to the first receptacle such that the first docking member can contact the collimator to remove the collimator from the first receptacle. The collimator is coupled to the first docking member while the collimator is removed from the first receptacle.

Abstract: The imaging system has two detectors which can be rotated in a circular path about an object with the angular displacement between the detectors and their radial position with respect to the axis being adjustable. Preferably, the distance of the detectors from the lateral axis is adjustable to increase resolution of the system. A gantry has supports for drive gear rings for the detectors with radial motion mechanisms connecting one detector to the interior surface of a drive gear ring and the other to the exterior of its drive gear ring via a support arm. A drive gear and idler gear move one detector along the circular path and a radial drive motor moves the detectors radially with respect to the axis.

Abstract: The imaging system has two detectors which can be rotated in a circular path about an object with the angular displacement between the detectors and their radial position with respect to the axis being adjustable. Preferably, the distance of the detectors from the lateral axis is adjustable to increase resolution of the system. A gantry has supports for drive gear rings for the detectors with radial motion mechanisms connecting one detector to the interior surface of a drive gear ring and the other to the exterior of its drive gear ring via a support arm. A drive gear and idler gear move one detector along the circular path and a radial drive motor moves the detectors radially with respect to the axis.

Abstract: A nuclear medicine imaging system provides three-axis linear and rotary detector motion. The imaging system includes an overhead gantry, which includes a carriage supported above the object and movable in translation along a first horizontal axis. Support arms are suspended downward from the carriage and are movable along a second horizontal axis perpendicular to the first horizontal axis. A detector is coupled to a lower end of each support arm. Each support arm is retractably extendible along a substantially vertical axis, and each detector is pivotable about a horizontal axis parallel to the first horizontal axis. Each support arm cooperates with the carriage to enable the corresponding detector to be positioned at multiple angular positions about a longitudinal axis corresponding to multiple projection angles by using combinations of independent linear movements of the detectors along any of three perpendicular axes.

Abstract: An improved image acquisition system allows the angular displacement between two detectors to be adjusted between 90° and 180° to reduce the imaging time for both 360° and 180° scans. A patient table is displaced vertically and horizontally from a lateral axis to allow the body of a patient to be positioned next to the detectors and to improve resolution.

Abstract: An improved image acquisition system allows the angular displacement between two detectors to be adjusted between 90° and 180° to reduce the imaging time for both 360° and 180° scans. A patient table is displaced vertically and horizontally from a lateral axis to allow the body of a patient to be positioned next to the detectors and to improve resolution.