Patents by Inventor Paul J. Cote

Paul J. Cote has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9310321
    Abstract: A system and associated method for quickly and automatically determining if the safety and performance of a gun tube have been compromised by firing damage or by an excessive number of fatigue cycles. An electromagnetic resonant cavity inspection provides a means of rapidly evaluating the health of the gun tube by monitoring the resonant frequencies that evolve from microwave signals introduced into the cavity or bore of the gun tube. This approach exploits the high sensitivity of the electromagnetic cavity resonance phenomena. Defects and degradation in the structure's cavity produce quantifiable changes in the quality factor, frequency shifts, and mode splitting.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: April 12, 2016
    Assignee: The United States of America as Represented by the Secretary of the Army
    Inventors: Mark Johnson, Paul J. Cote, Sara Lorene Makowiec, Joseph Carter
  • Patent number: 7511027
    Abstract: A method for the treatment for hepatitis delta infection in a host, that includes administering an effective amount of a nucleoside or a nucleoside analog that suppresses the expression of the hepatitis B surface or preS1 antigen in the host 100-fold or more relative to pretreatment values in vivo; or to not more than 1 microgram per milliliter in vivo. In a preferred embodiment, the nucleoside is L-FMAU, or a pharmaceutically acceptable salt or prodrug thereof.
    Type: Grant
    Filed: November 22, 2002
    Date of Patent: March 31, 2009
    Assignees: Georgetown University, University of Georgia Research Foundation, Inc.
    Inventors: John L. Casey, Brent E. Korba, Paul J. Cote, John L. Gerin, Bud C. Tennant, Chung K. Chu
  • Patent number: 6670342
    Abstract: A method for the treatment for hepatitis delta infection in a host, that includes administering an effective amount of a nucleoside or a nucleoside analog that suppresses the expression of the hepatitis B surface or preS1 antigen in the host 100-fold or more relative to pretreatment values in vivo; or to not more than 1 microgram per milliliter in vivo. In a preferred embodiment, the nucleoside is L-FMAU, or a pharmaceutically acceptable salt or prodrug thereof.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: December 30, 2003
    Assignees: Georgetown University, Cornell Research Foundation, Inc., University of Georgia Research Foundation, Inc.
    Inventors: John L. Casey, Brent E. Korba, Paul J. Cote, John L. Gerin, Bud C. Tennant, Chung K. Chu
  • Publication number: 20030158149
    Abstract: A method for the treatment for hepatitis delta infection in a host, that includes administering an effective amount of a nucleoside or a nucleoside analog that suppresses the expression of the hepatitis B surface or preS1 antigen in the host 100-fold or more relative to pretreatment values in vivo; or to not more than 1 microgram per milliliter in vivo. In a preferred embodiment, the nucleoside is L-FMAU, or a pharmaceutically acceptable salt or prodrug thereof.
    Type: Application
    Filed: November 22, 2002
    Publication date: August 21, 2003
    Inventors: John L. Casey, Brent E. Korba, Paul J. Cote, John L. Gerin, Bud C. Tennant, Chung K. Chu
  • Publication number: 20020160980
    Abstract: A method for the treatment for hepatitis delta infection in a host, that includes administering an effective amount of a nucleoside or a nucleoside analog that suppresses the expression of the hepatitis B surface or preS1 antigen in the host 100-fold or more relative to pretreatment values in vivo; or to not more than 1 microgram per milliliter in vivo. In a preferred embodiment, the nucleoside is L-FMAU, or a pharmaceutically acceptable salt or prodrug thereof.
    Type: Application
    Filed: March 29, 2001
    Publication date: October 31, 2002
    Inventors: John L. Casey, Brent E. Korba, Paul J. Cote, John L. Gerin, Bud C. Tennant, Chung K. Chu
  • Patent number: 6361508
    Abstract: A monitor device for monitoring the activity of an individual to provide an alarm for anomalous by the individual. The device includes a triaxial accelerometer adapted to measure simultaneously measure acceleration in three orthogonal, linear axes and generate a voltage output identifying the amplitude and frequency of detected motion by the individual in each axis. Also included is interface electronics for receiving the voltage outputs and buffering the voltage outputs to generate a first reference voltage for each axis of the accelerometer. Amplifier electronics amplifies each voltage output and compares each voltage output to the first reference voltage to produce a digital signal. A microcontroller receives the digital signal to compare it to an adjustable second reference voltage.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: March 26, 2002
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Mark A. Johnson, Paul J. Cote
  • Patent number: 6072400
    Abstract: An electronic light source which replaces the hazardous tritium light sou used in the existing Muzzle Reference System (MRS) found on the M1 Series of tanks. The MRS is mounted near the muzzle end of the gun (opposite the breech) and is used by tank gunness to measure gun deflection for calibration of the tank's fire control computer to optimize accuracy. The electronic light source is an LED which is activated by the pulses from a microcontroller based on the input received from a small, low power, omnidirectional motion sensor which detects the movement of the tank mounted on the tank. In the current implementation, the motion sensor comprises a conductive rolling sphere in a cylindrical chamber having a conductive wall with one electrical pole and end plates electrically insulated from the conductive wall and having the other electrical pole such that movement of the element caused by movement of the cylinder will generate intermittent electrical contact between one end plate and the cylinder wall.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: June 6, 2000
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Mark A. Johnson, Paul J. Cote
  • Patent number: 5879309
    Abstract: A motion detection device for monitoring patient movement. The device includes a sensor adapted to generate a voltage from mechanical vibrations and a circuit in operable relationship with the voltage for generating an alarm upon detection of a predetermined signal. The circuit provides a fixed impedance to the sensor. A micro controller is used for analyzing the signal to select from first and second conditions by sensing activity within sequences of preselected time intervals. The first condition represents a medical condition and the second condition represents casual motion. A switch is used for setting a time interval and a total sampling time for the micro controller. An alarm signal generates an alarm upon detection by the microprocessor of a predetermined activity. The preferred sensor comprises a housing having an outer shell and a hollow spherical opening therein.
    Type: Grant
    Filed: August 11, 1997
    Date of Patent: March 9, 1999
    Inventors: Mark A. Johnson, Paul J. Cote
  • Patent number: 5597527
    Abstract: The disclosure is of apparatus for determining the transformation characteristics of a metal alloy by treating the alloy to render it austenitic and then monitoring the isothermal decomposition of the austenite by measuring the magnetic change in the alloy.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: January 28, 1997
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventor: Paul J. Cote