Patents by Inventor Paul J Gleason
Paul J Gleason has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10661072Abstract: A device for delivery of TENS current, attachable to a handheld skin treatment device with a mechanical motion source, comprises a housing for mounting on the handheld skin treatment device, with a conductive skin contact head with first and second electrodes for receiving a TENS signal as a voltage established between the electrodes and a connector mounted in or on the housing and configured to interface with the mechanical motion source to receive the motion of the motion source. The device has an energy converter in the housing to convert the motion into electrical current, a power control circuit for receiving the electrical current and converting it into at least one power supply output voltage; and a signal generation circuit connected to the at least one the power supply output voltage for producing as an output a TENS signal for delivery to skin.Type: GrantFiled: May 25, 2018Date of Patent: May 26, 2020Assignee: NSE Products, Inc.Inventors: Dale G. Kern, Kevin S. Oberkramer, Jared H. Nathanson, Robert D. Miller, Paul J. Gleason
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Publication number: 20180361137Abstract: A device for delivery of TENS current, attachable to a handheld skin treatment device with a mechanical motion source, comprises a housing for mounting on the handheld skin treatment device, with a conductive skin contact head with first and second electrodes for receiving a TENS signal as a voltage established between the electrodes and a connector mounted in or on the housing and configured to interface with the mechanical motion source to receive the motion of the motion source. The device has an energy converter in the housing to convert the motion into electrical current, a power control circuit for receiving the electrical current and converting it into at least one power supply output voltage; and a signal generation circuit connected to the at least one the power supply output voltage for producing as an output a TENS signal for delivery to skin.Type: ApplicationFiled: May 25, 2018Publication date: December 20, 2018Inventors: Dale G. Kern, Kevin S. Oberkramer, Jared H. Nathanson, Robert D. Miller, Paul J. Gleason
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Publication number: 20160145676Abstract: The present invention provides systems and methods for analysis of samples, particularly biological and environmental sample to detect biomolecules of interest contained therein. A variety of system components are described herein, including, but not limited to, components for sample handling, mixing of materials, sample processing, transfer of materials, and analysis of materials. The invention further provides mechanisms for combining and integrating the different components and for housing, moving, and storing system components or the system as a whole. The systems may include any one or more or all of these components. The system finds particular use when employed for analysis of nucleic acid molecule using mass spectrometry, however, the invention is not limited such specific uses.Type: ApplicationFiled: November 20, 2015Publication date: May 26, 2016Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson, Ronald K. Bergold, Robert D. Miller, Kevin S. Oberkramer
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Publication number: 20160116379Abstract: Provided herein are apparatuses, systems, kits and methods for sterilely delivering fluid to an elongated swab. In particular, provided herein are apparatuses configured to sterilely deliver a desired fluid to a swab contained within a swab housing.Type: ApplicationFiled: October 22, 2015Publication date: April 28, 2016Inventors: James C. Hannis, Sherilynn Manalili Wheeler, Thomas N. Chiesl, Jared J. Drader, Steven A. Hofstadler, Ronald K. Bergold, Paul J. Gleason, Zachary T. Hannis
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Publication number: 20160104610Abstract: The invention relates generally to sample ionization, and provides ionization probe assemblies, systems, computer program products, and methods useful for this purpose.Type: ApplicationFiled: October 19, 2015Publication date: April 14, 2016Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson
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Patent number: 9194877Abstract: The present invention provides systems and methods for analysis of samples, particularly biological and environmental sample to detect biomolecules of interest contained therein. A variety of system components are described herein, including, but not limited to, components for sample handling, mixing of materials, sample processing, transfer of materials, and analysis of materials. The invention further provides mechanisms for combining and integrating the different components and for housing, moving, and storing system components or the system as a whole. The systems may include any one or more or all of these components. The system finds particular use when employed for analysis of nucleic acid molecule using mass spectrometry, however, the invention is not limited such specific uses.Type: GrantFiled: July 15, 2010Date of Patent: November 24, 2015Assignee: IBIS BIOSCIENCES, INC.Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson, Ronald K. Bergold, Robert D. Miller, Kevin S. Oberkramer
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Patent number: 9165740Abstract: The invention relates generally to sample ionization, and provides ionization probe assemblies, systems, computer program products, and methods useful for this purpose.Type: GrantFiled: August 4, 2014Date of Patent: October 20, 2015Assignee: IBIS BIOSCIENCES, INC.Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson
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Patent number: 9027730Abstract: Systems, computer program products, and methods useful for handling or managing microplates are provided.Type: GrantFiled: September 16, 2013Date of Patent: May 12, 2015Assignee: IBIS Biosciences, Inc.Inventors: Steven A. Hofstadler, Jared J. Drader, Jose R. Gutierrez, Paul J. Gleason, Rex O. Bare, Robert D. Miller, Jeffrey C. Smith, Kevin S. Oberkramer, Ronald K. Bergold
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Patent number: 9023655Abstract: Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.Type: GrantFiled: December 10, 2013Date of Patent: May 5, 2015Assignee: IBIS Biosciences, Inc.Inventors: Steven A. Hofstadler, Jared J. Drader, Jose R. Gutierrez, Paul J. Gleason, Rex O. Bare, Robert D. Miller, Jeffrey C. Smith
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Patent number: 8950604Abstract: The present invention provides devices, apparatuses, and systems for lifting and mounting of clinical- and research-related equipment. In particular, the present invention provides a lift and mount system for mass spectrometers (e.g., for time of flight (TOF) mass spectrometers (MS)).Type: GrantFiled: July 15, 2010Date of Patent: February 10, 2015Assignee: IBIS Biosciences, Inc.Inventors: Jared J. Drader, Steven A. Hofstadler, Jose R. Gutierrez, Paul J. Gleason, Andrew J. Scherer, Rex O. Bare
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Publication number: 20150014548Abstract: The invention relates generally to sample ionization, and provides ionization probe assemblies, systems, computer program products, and methods useful for this purpose.Type: ApplicationFiled: August 4, 2014Publication date: January 15, 2015Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson
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Publication number: 20140224042Abstract: Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.Type: ApplicationFiled: December 10, 2013Publication date: August 14, 2014Applicant: IBIS BIOSCIENCES, INC.Inventors: Steven A. Hofstadler, Jared J. Drader, Jose R. Gutierrez, Paul J. Gleason, Rex O. Bare, Robert D. Miller, Jeffrey C. Smith
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Patent number: 8796617Abstract: The invention relates generally to sample ionization, and provides ionization probe assemblies, systems, computer program products, and methods useful for this purpose.Type: GrantFiled: January 3, 2012Date of Patent: August 5, 2014Assignee: Ibis BioSciences, Inc.Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson
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Publication number: 20140154043Abstract: Systems, computer program products, and methods useful for handling or managing microplates are provided.Type: ApplicationFiled: September 16, 2013Publication date: June 5, 2014Applicant: IBIS BIOSCIENCES, INC.Inventors: Steven A. Hofstadler, Jared J. Drader, Jose R. Gutierrez, Paul J. Gleason, Rex O. Bare, Robert D. Miller, Jeffrey C. Smith, Kevin S. Oberkramer, Ronald K. Bergold
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Patent number: 8609430Abstract: Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.Type: GrantFiled: August 27, 2012Date of Patent: December 17, 2013Assignee: Ibis Biosciences, Inc.Inventors: Steven A. Hofstadler, Jared J. Drader, Jose R. Gutierrez, Paul J. Gleason, Rex O. Bare, Robert D. Miller, Jeffrey C. Smith
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Publication number: 20130302787Abstract: A device for extraction or isolation of an analyte, such as a nucleic acid, a protein, or a cell, from a sample, and in particular from a biological sample, is described. Methods of using the device are also described. Further processes, such as amplification of the isolated analyte, may also be carried out within the device.Type: ApplicationFiled: May 7, 2013Publication date: November 14, 2013Applicants: Northwestern University, Northwestern Global Health Foundation, Quidel CorporationInventors: Abhishek K. Agarwal, Renana Ashkenazi, Mark J. Fisher, Paul J. Gleason, Jacqueline R. Groves, Henry H. Hsu, David M. Kelso, Sally M. McFall, Mark E. Mossberg, Zaheer Parpia, Kunal Sur, Tom Westberg
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Patent number: 8534447Abstract: Systems, computer program products, and methods useful for handling or managing microplates are provided.Type: GrantFiled: September 16, 2009Date of Patent: September 17, 2013Assignee: Ibis Biosciences, Inc.Inventors: Steven A. Hofstadler, Jared J. Drader, Jose R. Gutierrez, Paul J. Gleason, Rex O. Bare, Robert D. Miller, Jeffrey C. Smith, Kevin S. Oberkramer, Ronald K. Bergold
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Publication number: 20130059372Abstract: Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.Type: ApplicationFiled: August 27, 2012Publication date: March 7, 2013Applicant: IBIS BIOSCIENCES, INC.Inventors: Steven A. Hofstadler, Jared J. Drader, Jose R. Gutierrez, Paul J. Gleason, Rex O. Bare, Robert D. Miller, Jeffrey C. Smith
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Patent number: 8252599Abstract: Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.Type: GrantFiled: August 30, 2011Date of Patent: August 28, 2012Assignee: Ibis Biosciences, Inc.Inventors: Steven A. Hofstadler, Jared J. Drader, Jose R. Gutierrez, Paul J. Gleason, Rex O. Bare, Robert D. Miller, Jeffrey C. Smith
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Publication number: 20120115213Abstract: The present invention provides systems and methods for analysis of samples, particularly biological and environmental sample to detect biomolecules of interest contained therein. A variety of system components are described herein, including, but not limited to, components for sample handling, mixing of materials, sample processing, transfer of materials, and analysis of materials. The invention further provides mechanisms for combining and integrating the different components and for housing, moving, and storing system components or the system as a whole. The systems may include any one or more or all of these components. The system finds particular use when employed for analysis of nucleic acid molecule using mass spectrometry, however, the invention is not limited such specific uses.Type: ApplicationFiled: July 15, 2010Publication date: May 10, 2012Applicant: IBIS BIOSCIENCES, INC.Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared H. Nathanson, Ronald K. Bergold, Robert D. Miller, Kevin S. Oberkramer