Patents by Inventor Paul J. Golueke

Paul J. Golueke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cloning of transgenic unglulates comprising artificial chromosomes
    Patent number: 7652192
    Abstract: The invention is directed in part to totipotent cells that have one or more artificial chromosomes; processes for producing such cells; processes for using such cells (e.g., nuclear transfer); transgenic embryos and transgenic animals cloned from such cells; and processes for producing such embryos and animals.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: January 26, 2010
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Erik J. Forsberg, Kelly S. Mallon, Paul J. Golueke, Michael D. Bishop
  • Cultured inner cell mass cell lines derived from bovine or porcine embryos
    Patent number: 5905042
    Abstract: Novel cultured inner cell mass (CICM) cells, and cell lines, derived from ungulates, in particular, pigs and cows, and methods for their preparation are provided. The subject CICMs possess similar morphology and express cell markers identically or substantially similarly to ICMs of undifferentiated developing embryos for prolonged culturing periods. Heterologous DNAs may be introduced into the subject CICM cells and cell lines to produce transgenic cells useful for the production of transgenic embryos, fetuses and/or offspring, e.g., by nuclear transfer procedures.
    Type: Grant
    Filed: April 1, 1996
    Date of Patent: May 18, 1999
    Assignee: University of Massachusetts, A Public Institution of Higher Education of the Commonwealth of Massachusetts, as Represented by its Amherst Campus
    Inventors: Steven L. Stice, Paul J. Golueke