Abstract: A system includes a controller with at least one processor and at least one non-transitory, tangible memory on which instructions are recorded for executing a method for obtaining a profile of a lens capsule of an eye. The profile is represented by respective central surfaces and respective equatorial surfaces separated at respective transition points. The controller is configured to obtain imaging data for a portion of the lens capsule visible through a pupil of the eye. The imaging data is transformed to an adjusted frame of reference and fitted to the respective central surfaces in a predefined central region of the lens capsule. The profile is obtained based on a set of fitting parameters for the respective central and equatorial surfaces. The respective central surfaces and respective equatorial surfaces may be represented as elliptical cones and skewed parabolas, respectively.

Abstract: A system includes a controller with at least one processor and at least one non-transitory, tangible memory on which instructions are recorded for executing a method for obtaining a profile of a lens capsule of an eye. The profile is represented by respective central surfaces and respective equatorial surfaces separated at respective transition points. The controller is configured to obtain imaging data for a portion of the lens capsule visible through a pupil of the eye. The imaging data is transformed to an adjusted frame of reference and fitted to the respective central surfaces in a predefined central region of the lens capsule. The profile is obtained based on a set of fitting parameters for the respective central and equatorial surfaces. The respective central surfaces and respective equatorial surfaces may be represented as elliptical cones and skewed parabolas, respectively.

Abstract: A system includes a controller with at least one processor and at least one non-transitory, tangible memory on which instructions are recorded for executing a method for obtaining a profile of a lens capsule of an eye. The profile is represented by respective central surfaces and respective equatorial surfaces separated at respective transition points. The controller is configured to obtain imaging data for a portion of the lens capsule visible through a pupil of the eye. The imaging data is transformed to an adjusted frame of reference and fitted to the respective central surfaces in a predefined central region of the lens capsule. The profile is obtained based on a set of fitting parameters for the respective central and equatorial surfaces. The respective central surfaces and respective equatorial surfaces may be represented as elliptical cones and skewed parabolas, respectively.

Abstract: Drug delivery devices, and methods of delivering pharmaceutically active agents to a target tissue within a body using such devices, are disclosed. One drug delivery device includes a body having an internal surface for disposing on a target tissue and a well having an opening to the internal surface. An inner core comprising a drug containing portion and an expandable material is disposed in the well.