Patents by Inventor Paul K. Smith
Paul K. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20030187248Abstract: Novel arylisothiocyanate compounds are described that are useful for activating alcohol-containing macromolecules, for example polyethyleneglycols and cellulose, for covalent linkage to amino-groups of biomolecules, for example polypeptides such as antibodies, enzymes, and proteins.Type: ApplicationFiled: March 25, 2002Publication date: October 2, 2003Inventor: Paul K. Smith
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Publication number: 20020179542Abstract: A water-insoluble polymeric oxidizing medium is contemplated that has a plurality of polymerized N-pyridinium vinylbenzyl triiodide or tribromide moieties whose pyridinium rings bear two substituents, R1 and R2, that are independently a hydrido or a C1-C4 alkyl group, and correspond in structure to the formula 1Type: ApplicationFiled: December 17, 2001Publication date: December 5, 2002Inventors: Paul K. Smith, Timothy J. Badger
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Patent number: 6063287Abstract: A process is disclosed for the removal of algae-associated odorant from fresh water by contacting such water with cyclodextrin and recovering the water so contacted.Type: GrantFiled: September 17, 1998Date of Patent: May 16, 2000Assignee: Affiniti, LLCInventors: Paul K. Smith, Eugene P. Bergemann
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Patent number: 6017943Abstract: The present invention provides a class of compounds having the formula:Y--R--CH.sub.2 --CH.sub.2 --[O--CH.sub.2 --CH.sub.2 ].sub.n --R'--Y'wherein n is an integer from about 5 to about 200; R is carbamate, urea, or amide; R' is carbamate, urea, amide, or oxygen; Y is 4-phenylmalemimido or 3-phenylmaleimido; and Y' is 4-phenylmalemimido, 3-phenylmaleimido, methyl or hydrogen. The present invention also provides various hemoglobin compositions modified with the class of compounds of the present invention, processes for preparing these compositions, as well as pharmaceutical compositions comprising these compositions.Type: GrantFiled: February 4, 1998Date of Patent: January 25, 2000Assignee: Albert Einstein College of Medicine of Yeshiva UniversityInventors: A. Seetharama Acharya, Belur N. Manjula, Paul K. Smith
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Patent number: 5908557Abstract: A process for the separation of pentavalent arsenic from an aqueous solution using an N-alkyl pyridinium-containing adsorption medium is disclosed. An oxidizing medium and process for the oxidation of trivalent arsenic to pentavalent arsenic with removal of the pentavalent arsenic so formed is also disclosed.Type: GrantFiled: May 12, 1997Date of Patent: June 1, 1999Assignee: NTEC Solutions, Inc.Inventors: Paul K. Smith, Eugene P. Bergemann
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Patent number: 5855789Abstract: A process for removing contaminating levels of selenium from a contaminated aqueous solution is disclosed. That process includes providing a vessel or flow-permissive container containing a water-insoluble polymeric adsorption medium having a plurality of polymerized C.sub.1 -C.sub.4 N-alkylated pyridinium-containing adsorption sites. An influent of an aqueous solution having a total selenium concentration of about 10 to about 1000 parts per billion is introduced to the vessel or flow-permissive container to contact the insoluble polymeric adsorption medium. The solution is maintained in contact with that insoluble adsorption medium for a time period sufficient for the medium to bind the selenium in the contacting solution. The resulting aqueous solution is discharged from the vessel as an effluent having a total selenium concentration whose ratio to the total selenium concentration of the influent is about zero to about 10.sup.-3.Type: GrantFiled: April 1, 1997Date of Patent: January 5, 1999Assignee: NTEC Solutions, Inc.Inventors: Paul K. Smith, Eugene P. Bergemann
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Patent number: 5750725Abstract: The present invention provides a class of compounds having the formula:Y--R--CH.sub.2 --CH.sub.2 --?O--CH.sub.2 --CH.sub.2 !.sub.n --R'--Y'wherein n is an integer from about 5 to about 200; R is carbamate, urea, or amide; R' is carbamate, urea, amide, or oxygen; Y is 4-phenylmalemimido or 3-phenylmaleimido; and Y' is 4-phenylmalemimido, 3-phenylmaleimido, methyl or hydrogen. The present invention also provides various hemoglobin compositions modified with the class of compounds of the present invention, processes for preparing these compositions, as well as pharmaceutical compositions comprising these compositions.Type: GrantFiled: September 26, 1996Date of Patent: May 12, 1998Assignee: Albert Einstein College of Medicine of Yeshiva University, a Division of YeshivaInventors: A. Seetharama Acharya, Belur N. Manjula, Paul K. Smith
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Patent number: 5746922Abstract: A process for removing contaminating levels of hexavalent chromium ion ?Cr(VI)! from a concentrated aqueous solution of sodium sulfate. That process includes providing a vessel containing a water-insoluble adsorption medium having a plurality of polymerized pyridyl-containing adsorption sites. An influent of an aqueous solution of about 1.0 to about 2.0 molar (e.g., saturated) sodium sulfate having a total hexavalent chromium ion concentration of up to about 1000 parts per million, to the vessel to contact the insoluble adsorption medium. The solution is maintained in contact with that insoluble adsorption medium for a time period sufficient for the medium to bind the hexavalent chromium ions in the contacting solution. The resulting aqueous solution is discharged from the vessel as an effluent having a total hexavalent chromium ion concentration whose ratio to the total hexavalent chromium ion concentration of the influent is about zero to about 25.0.times.10.sup.-6.Type: GrantFiled: January 27, 1997Date of Patent: May 5, 1998Assignee: NTEC Solutions, Inc.Inventors: Paul K. Smith, Eugene P. Bergemann
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Patent number: 5667352Abstract: A locking system for extension members on portable lifts or the like has a wedge block with a jaw face on one side and a sloped wedge face on the opposite side engaging a complementing fixed sloped face so that when the wedge block is moved upwardly the complementing faces cause the wedge block to also move horizontally into clamping position by way of the jaw face. The wedge block is moved upwardly responsive to turning of a screw threaded into the block.Type: GrantFiled: April 18, 1994Date of Patent: September 16, 1997Assignee: Genie IndustriesInventors: Richard M. Curtin, Paul K. Smith, Matthew G. Kraemer
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Patent number: 5645142Abstract: Apparatus for braking relative vertical movement between two vertical members includes a ramp mounted on one of the members to oppose a vertical face on the other. If the ramp member accelerates downwardly a wedging roller is wedged between the ramp and the vertical face. This roller is on a slide rod which normally compresses a spring carried at the bottom of the ramp, but downward acceleration on the ramp results in expansion of the spring and movement of the wedging roller into wedging position to stop the acceleration.Type: GrantFiled: April 18, 1994Date of Patent: July 8, 1997Assignee: Genie IndustriesInventors: Matthew G. Kraemer, Richard M. Curtin, Paul K. Smith
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Patent number: 5584363Abstract: A swing-up stabilizer for a portable lift has a bracing strut with a pivoted locking mechanism at its upper end including a locking plate on the strut which is spring biased into a tilted locking position biting the strut when the stabilizer is in an active ground engaging position or swung into a raised storage position located past an "at center" position whereat the strut is aligned with a pivotal connection between the strut and stabilizer.Type: GrantFiled: April 18, 1994Date of Patent: December 17, 1996Assignee: Genie IndustriesInventors: Richard M. Curtin, Paul K. Smith, Matthew G. Kraemer
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Patent number: 5585484Abstract: The present invention provides a class of compounds having the formula:Y--R--CH.sub.2 --CH.sub.2 --[O--CH.sub.2 --CH.sub.2 ].sub.n --R'--y'wherein n is an integer from about 5 to about 200; R is carbamate, urea, or amide; R' is carbamate, urea, amide, or oxygen; Y is 4-phenylmalemimido or 3-phenylmaleimido; and Y' is 4-phenylmalemimido, 3-phenylmaleimido, methyl or hydrogen. The present invention also provides various hemoglobin compositions modified with the class of compounds of the present invention, processes for preparing these compositions, as well as pharmaceutical compositions comprising these compositions.Type: GrantFiled: April 19, 1995Date of Patent: December 17, 1996Assignee: Albert Einstein College of Medicine of Yeshiva University, A Division of Yeshiva UniversityInventors: A. Seetharama Acharya, Belur N. Manjula, Paul K. Smith
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Patent number: 5515945Abstract: A multi-stage mast assembly has its mast stages stacked front to back when retracted and has front-to-back guide rollers and side-to-side guide rollers between the mast stages and a front carriage frame. An extrusion is used for the mast stages and the carriage frame. The extrusion has a central hollow rectangular column, inwardly facing channels at the front corners, outwardly directed flanges at the back corners, and pairs of central stub flanges at the front and back.Type: GrantFiled: April 18, 1994Date of Patent: May 14, 1996Assignee: Genie Industries, Inc.Inventors: Paul K. Smith, Richard M. Curtin, Matthew G. Kraemer
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Patent number: 5337858Abstract: A lift has a base frame supported on a pair of screw jacks and a pair of support legs when a multi-stage mast on the lift is to be raised. The support legs are slide mounted in guides and each is downwardly biased away from a control switch on the base frame so that the switch is open unless the leg is loaded by the weight of the lift. A transport carriage is mounted to roll on sloped tracks on the base frame and is connected to the base frame by a hydraulic cylinder unit which functions when activated to pull the carriage downwardly into ground engagement to take the load of the lift from the jacks and support legs. A control circuit prevents the mast from being raised while the lift is supported on the carriage.Type: GrantFiled: January 19, 1993Date of Patent: August 16, 1994Assignee: Genie IndustriesInventors: Willi B. Neubauer, Paul K. Smith, Philip J. Harvey
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Patent number: 4839295Abstract: Cu.sup.+ produced during the reaction of protein with alkaline Cu.sup.++ can be monitored by measuring the absorbance at 562 nm of the intense purple complex formed with the ion of bicinchoninic acid (BCA). The color produced is stable and increases in a linear fashion over a broad working range of increasing protein concentration. Since BCA is stable, it is incorporated in the reagent formulation at the start of the reaction. Thus, the method offers mechanical simplification over the method described by Lowry et al.Type: GrantFiled: May 26, 1987Date of Patent: June 13, 1989Assignee: Pierce Chemical CompanyInventor: Paul K. Smith
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Patent number: 4657218Abstract: An improved easily-adjustable chair pedestal having two principal tubular members, including a base member and a pedestal tube therein, which are axially adjustable to an infinite number of positions and are clamped together at the desired relative positions. An off-center coil spring, which is held in proper vertical alignment by support structure, biases the pedestal tube upwardly. A clamp screw passes through an orifice in the base member and through a slot in the pedestal tube and is threadedly engaged with a locking block, located inside the pedestal tube in space provided by the off-center location of the spring, to hold the principal tubular members in position.Type: GrantFiled: January 21, 1986Date of Patent: April 14, 1987Assignee: J. I. Case CompanyInventors: James W. Scheberle, Paul K. Smith
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Patent number: 4448764Abstract: There is disclosed an effective direct-acting iodinating reagent for biological specimens which, because it is direct, avoids the necessity of having present at the same time both an oxidizing agent and sodium iodide. The reagent is a conjugate of an iodous ion and a water insoluble support. The manner of conjugation is such that the ion is complexed onto the surface of the support but is still free to react with groups in proteins susceptible to iodination and thus be transferred to the biological specimen being iodinated. Apart from the advantage of being direct-acting, the reagent has those desirable attributes which are associated with water insoluble oxidants.Type: GrantFiled: July 6, 1982Date of Patent: May 15, 1984Assignee: Pierce Chemical CompanyInventors: Paul K. Smith, Dennis C. Klenk
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Patent number: 4436718Abstract: An improved oxidant useful in mediating the iodination of biological specimens containing tyrosyl or synthetically incorporated phenolic residues is disclosed. The oxidant is water insoluble, is easy to handle, and can be prepared with a determinable oxidizing capacity. An illustrated oxidant is a polystyrene bead having covalently attached to its surface N-chlorobenzenesulfonamide groups.Type: GrantFiled: October 13, 1981Date of Patent: March 13, 1984Assignee: Pierce Chemical CompanyInventor: Paul K. Smith
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Patent number: 4394259Abstract: Vacuum pneumatic conveying apparatus and method are utilized to transfer food products, such as fish, from a boat to a processing factory directly or via a tender vessel. Fish products such as salmon, are withdrawn from a fishing boat through an intake nozzle of a pneumatic vacuum system and entrained in an air flow, upwardly through inlet or receiving conduits of a vacuum, pneumatic, conveying system, and on through a product separator of an in line assembly of an upper product separator and a lower liquid separator. Salmon continue on flying out of the product separator and commence their downwardly momentum and gravity induced travel through discharge conduits, encompassing essentially non flowing air maintained under continuing vacuum.Type: GrantFiled: October 27, 1981Date of Patent: July 19, 1983Assignee: TEMCO, Inc.Inventors: John R. Benny, Robert W. Buher, Paul K. Smith
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Patent number: 3979506Abstract: New radioactive compounds are disclosed which are useful for labeling proteins and the like for radioimmunoassay techniques. These compounds are imido esters of radioactive substituted hydroxy or alkoxy phenyls.Type: GrantFiled: October 11, 1974Date of Patent: September 7, 1976Assignee: Pierce Chemical CompanyInventor: Paul K. Smith