Abstract: Techniques for facilitating reservations between a first creative entity and a first venue. Digital audio data for a first creative entity is analyzed to determine acoustic attributes. A plurality of potential venues are determined. A machine learning model is used to calculate an estimated demand metric for the first creative entity for each of the plurality of potential venues, based on a venue profile for the respective venue and acoustic attributes for the first creative entity. Two or more venues are selected and a proposed itinerary is created. A digital order is generated based on the proposed itinerary. User profile data for the first creative entity is updated, upon successful completion of the digital order, and a digital transaction is generated to automatically charge a determined first amount to an account for the first venue and to transfer a determined second amount to an account for the first creative entity.

Abstract: Prophylaxis or treatment of allergic airway inflammatory activity is described using Bifidobacterium longum NCIMB 41003. Also described is an exopolysaccharide which comprises the structure Formula (I). The polysaccharide may be used for treating or preventing undesirable inflammatory activity.

Abstract: The invention relates to materials and methods of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein comprising contacting the oxidized carbohydrate moiety with an activated water soluble polymer under conditions that allow conjugation and analyzing the conjugation using 2D NMR analysis. More specifically, the present invention relates to the aforementioned materials and methods wherein the water soluble polymer contains an active aminooxy group and wherein an oxime or hydrazone linkage is formed between the oxidized carbohydrate moiety and the active aminooxy group on the water soluble polymer, and wherein the conjugation is carried out in the presence of a nucleophilic catalyst.

Abstract: The present invention encompasses novel triterpene compounds of general formula I, wherein R3a, R3b, R11a, R11b, R31 and R32 are defined as in claim 1, which are suitable for the prevention and/or treatment of diseases mediated by 11 ?-HSD and the use thereof for preparing a medicament having the above-mentioned properties.

Abstract: The present invention encompasses novel triterpene compounds of general formula I, wherein R3a, R3b, R11a, R11b, R31 and R32 are defined as in claim 1, which are suitable for the prevention and/or treatment of diseases mediated by 11 ?-HSD and the use thereof for preparing a medicament having the above-mentioned properties.

Abstract: An adjustable hand grip mount detachably connected to the hand grips of a motorcycle for engaging one or more tie-straps connected to a transportation vehicle on which the motorcycle is supported. The adjustable hand grip mount includes a telescopic frame having a pair of tubular receptacles rotably connected thereto. The hand grips of the motorcycle are received within the receptacles and the telescopic frame is locked at a selected longitudinal extension. Strap holes are defined at the opposing ends of the telescopic frame to receive the tie straps which are secured thereto by tying or by the use of hooks, clips or other connectors commonly used with such tie straps.