Abstract: The present invention relates generally to devices comprising one or more microstructures that are used to relieve, treat or prevent pain. The devices are designed such that they are inserted into the superficial layers of the skin to achieve pain relief. The devices are designed such that the microstructures are able to grasp and secure to the skin. The devices may consist of microstructures in arrays that are attached to a backing to enable the devices to adhere to the skin. Also provided are wound closure systems that comprise one or more microstructure devices along with other components, such as protective covers and therapeutics. A variety of packaging specifications are disclosed, as is a dispenser apparatus configured to enable simple one-handed application of the devices. Methods described herein provide for treatment of pain.

Abstract: Implants for the fusion or fixation of two bone segments are described. For example, the implants can be used for the fusion or fixation of the sacroiliac joint. The implants can include fenestrations, have a rectilinear overall cross-sectional area, and have a curvature. Some implants can also be used to rescue failed implants.

Abstract: A wound closure device in the form of a force modulating deep skin staple. The deep skin staple includes a bridge portion extending along a longitudinal axis to support a first set of staple legs and an opposing second set of staple legs. Each staple leg coupled to the bridge portion via a spring arm. Each staple leg angled towards a middle section of the bridge portion. The staple legs designed to modulate forces with a wound down into the reticular dermis layer when applied to the wound.

Abstract: Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.

Abstract: A system for tracking adverse events may include at least one processing device programmed to receive a request from a user to record an adverse event experienced by a patient; receive a search term input by the user; identify, in an adverse event database and based on the search term, at least one database record for an adverse event, wherein the at least one database record includes an adverse event type and at least one characteristic; receive, via an input field, a rating of the at least one characteristic for the patient; generate an adverse event record based on the adverse event type and the rating; and store the adverse event record in an adverse event log.

Abstract: A wound cover device can include a backing, a micro-structure device, and one or more of a wound dressing and a skin replacement layer. The backing can be stretchable. The micro-structure device can include a plurality of fasteners, such as micro-staples, micro-pins, micro-barbs and the like, that can be used to attach the wound cover device to tissue such as skin. The micro-structure device can be stretchable to stretch with the backing. The micro-structure device can be configured such that the fasteners are positioned in a two-dimensional pattern or fill-in an interior portion of the wound dressing or skin replacement layer. The fasteners of the micro-structure device can extend through the wound dressing or skin replacement layer. The micro-structure device can additionally be placed around a perimeter or edge region of the backing.

Abstract: A wound closure device in the form of a force modulating deep skin staple. The deep skin staple includes a bridge portion extending along a longitudinal axis to support a first set of staple legs and an opposing second set of staple legs. Each staple leg coupled to the bridge portion via a spring arm. Each staple leg angled towards a middle section of the bridge portion. The staple legs designed to modulate forces with a wound down into the reticular dermis layer when applied to the wound.

Abstract: A wound closure device includes an elastic substrate and a plurality of microstructure arrays coupled to the elastic substrate via an adhesive layer. The device is long enough or wide enough to treat large wounds with the plurality of microstructure arrays distributed along a length of the wound.

Abstract: A wound closure device comprises a backing comprising a width configured to extend along at least a portion of a wound from a first end to a second end and a length configured to extend transversely across the wound, an adhesive layer coupled to the backing, a first micro-structure array attached to the backing proximate the first end, the first micro-structure array configured to extend transversely across the wound, a second micro-structure array attached to the backing proximate the second end, the second micro-structure array configured to extend transversely across the wound, and an elongate wound closure space between the first and second micro-structure arrays.

Abstract: Disclosed herein is a novel medical implement drying apparatus and a method for holding and drying certain medical implements during a reprocessing sequence. This is accomplished by forcing air through the apparatus. The apparatus and method disclosed herein is useful for many medical implements having a hollow casing. The medical implement drying apparatus is particularly well suited for use with a drying cabinet containing one or more of the medical implements during the drying process which will facilitate drying of the exterior of each medical implement, while the disclosed apparatus removes water and water vapor from the interior of each medical implement. Specialized holders, racks, and drying gas pumping systems are also disclosed.

Abstract: A wound closure device includes an elastic substrate and one or more microstructure arrays coupled to the elastic substrate via an adhesive layer. The device is long enough or wide enough to treat large wounds.

Abstract: An attachment device used to attach appliances to tissue can incorporate microstructures. A medical device system can comprise a coupling device comprising a base layer, a coupling attached to an air side of the base layer, a microstructure attached to a skin side of the base layer and a patient interaction feature, and an appliance comprising a structure mounted to the coupling to interface with the patient interaction feature. An appliance device comprises a base layer, an appliance structure attached to an air side of the base layer, and a microstructure attached to a skin side of the base layer. An appliance attachment system comprises an appliance, a first component comprising an adhesive backing containing microstructures that are configured to attach to skin, and a second component configured to attach the appliance to the first component.

Abstract: The present invention relates generally to devices comprising one or more microstructures that are used to relieve, treat or prevent pain. The devices are designed such that they are inserted into the superficial layers of the skin to achieve pain relief. The devices are designed such that the microstructures are able to grasp and secure to the skin. The devices may consist of microstructures in arrays that are attached to a backing to enable the devices to adhere to the skin. Also provided are wound closure systems that comprise one or more microstructure devices along with other components, such as protective covers and therapeutics. A variety of packaging specifications are disclosed, as is a dispenser apparatus configured to enable simple one-handed application of the devices. Methods described herein provide for treatment of pain.

Abstract: Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.

Abstract: Disclosed herein is a novel medical implement drying apparatus and a method for holding and drying certain medical implements during a reprocessing sequence. This is accomplished by forcing air through the apparatus. The apparatus and method disclosed herein is useful for many medical implements having a hollow casing. The medical implement drying apparatus is particularly well suited for use with a drying cabinet containing one or more of the medical implements during the drying process which will facilitate drying of the exterior of each medical implement, while the disclosed apparatus removes water and water vapor from the interior of each medical implement. Specialized holders, racks, and drying gas pumping systems are also disclosed.

Abstract: Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.

Abstract: Disclosed herein is a novel medical implement drying apparatus and a method for holding and drying certain medical implements during a reprocessing sequence. This is accomplished by forcing air through the apparatus. The apparatus and method disclosed herein is useful for many medical implements having a hollow casing. The medical implement drying apparatus is particularly well suited for use with a drying cabinet containing one or more of the medical implements during the drying process which will facilitate drying of the exterior of each medical implement, while the disclosed apparatus removes water and water vapor from the interior of each medical implement. Specialized holders, racks, and drying gas pumping systems are also disclosed.

Abstract: Disclosed herein is a novel medical implement drying apparatus and a method for holding and drying certain medical implements during a reprocessing sequence. This is accomplished by forcing air through the apparatus. The apparatus and method disclosed herein is useful for many medical implements having a hollow casing. The medical implement drying apparatus is particularly well suited for use with a drying cabinet containing one or more of the medical implements during the drying process which will facilitate drying of the exterior of each medical implement, while the disclosed apparatus removes water and water vapor from the interior of each medical implement. Specialized holders, racks, and drying gas pumping systems are also disclosed.

Abstract: A wound cover device can comprise a backing, a micro-structure device, and one or more of a wound dressing and a skin replacement layer. The backing can be stretchable The micro-structure device can comprise a plurality of fasteners, such as micro-staples, micro-pins, micro-barbs and the like, that can be used to attach the wound cover device to tissue such as skin. The micro-structure device can be stretchable to stretch with the backing. The micro-structure device can be configured such that the fasteners are positioned in a two-dimensional pattern or fill-in an interior portion of the wound dressing or skin replacement layer. The fasteners of the micro-structure device can extend through the wound dressing or skin replacement layer. The micro-structure device can additionally be placed around a perimeter or edge region of the backing.

Abstract: Systems, apparatus, and methods related to wound closure devices comprising one or more microstructures are described herein. In some embodiments, the wound closure devices include a backing and a microstructure array. The microstructure array may include a first portion, a second portion, and a bridge portion. The first portion and the second portion each include one or more microstructures configured to penetrate tissue. Additionally, the first portion and the second portion each include one or more expandable portions such that the wound closure device is configured to expand in length. The wound closure device is configured to grip tissue surrounding a wound to either close the wound or secure the tissue in place.