Patents by Inventor Paul Mark Henrichs

Paul Mark Henrichs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Light imaging contrast agents
    Patent number: 7014839
    Abstract: The present invention relates to the use of particulate materials as contrast agents in in vivo light imaging.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: March 21, 2006
    Assignee: Amersham Health AS
    Inventors: Jo Klaveness, Bjorn Fuglaas, Pål Rongved, Edvin Johannesen, Paul Mark Henrichs, Wolfgang Hans Heinrich Gunther, Edward Richard Bacon, John Luke Toner, Gregory Lynn McIntire, Vinay C. Desai
  • Methods of photoacoustic imaging
    Patent number: 6662040
    Abstract: The invention relates to a method of generating an image of an animate human or non-human animal body or part thereof. The method comprises administering to said body a physiologically tolerable contrast agent comprising a radiation absorbing component and/or a pressure inducing component, exposing said body to radiation, detecting pressure waves generated in said body by said radiation and generating an optoacoustic image therefrom of at least a part of said body containing the administered contrast agent.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: December 9, 2003
    Assignee: Amersham Health AS
    Inventors: Paul Mark Henrichs, Marten Eriksen, Pal Rongved, Wolfgang Hans Heinrich Gunther, Robert Allen Snow, Kenneth Robert Hollister, Gregory Lynn McIntire, Steven Blair Coffey
  • Light imaging contrast agents
    Publication number: 20030157021
    Abstract: The present invention relates to the use of particulate materials as contrast agents in in vivo light imaging.
    Type: Application
    Filed: November 1, 2002
    Publication date: August 21, 2003
    Inventors: Jo Klaveness, Bjorn Fuglaas, Pal Rongved, Edvin Johannesen, Paul Mark Henrichs, Wolfgang Hans Heinrich Gunther, Edward Richard Bacon, John Luke Toner, Gregory Lynn McIntire, Vinay C. Desai
  • Sonodynamic therapy using an ultrasound sensitizer compound
    Patent number: 6498945
    Abstract: A method of treatment of a human or animal body by sonodynamic therapy in which a sensitizer agent is administered to the body and the body is exposed to ultrasound to achieve a cytopathogenic effect at a site therein, wherein the said sensitizer agent is a physiologically tolerable substance which is capable of enhancing the cytopathogenic efficacy of said sonodynamic therapy. Preferably, the sensitizer agent is a water-soluble polymer compound or a conjugate thereof.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: December 24, 2002
    Assignee: Amersham Health AS
    Inventors: Jan Alan Alfheim, Paul Mark Henrichs, Eric Paul Hohenschuh, Edvin Wilheim Johannesen, William Anthony Sanderson, Robert Allen Snow
  • Use of acousto-optical and sonoluminescene contrast agents
    Patent number: 6424857
    Abstract: The invention relates inter alia to a method of generating information from an animate human or non-human animal body which method comprises: administering to said body a physiologically tolerable material capable of absorbing, scattering or emitting light at a wavelength in the range 300 to 1300 nm; subjecting at least a portion of said body to ultrasound irradiation; detecting light in the wavelength range 300 to 1300 nm from said portion of said body; and manipulating the detected light to generate said information.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: July 23, 2002
    Assignee: Amersham Health AS
    Inventors: Paul Mark Henrichs, Henry Raphael Wolfe
  • Compounds
    Patent number: 6350431
    Abstract: This invention provides a physiologically tolerable light imaging contrast agent compound having a molecular weight in the range 500 to 5000000 and containing at least two chromophores having delocalized electron systems as well as at least one polyalkylene oxide (PAO) moiety having a molecular weight in the range 60 to 100000.
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: February 26, 2002
    Assignee: Nycomed Imaging AS
    Inventors: Robert Allen Snow, Paul Mark Henrichs, Daniel Joseph Delecki, William Anthony Sanderson, Vinay Chandrakant Desai, Edward Bacon, Kenneth Robert Hollister, Eric Paul Hohenschuh
  • Light imaging contrast agents
    Publication number: 20010022963
    Abstract: The present invention relates to the use of particulate materials as contrast agents in in vivo light imaging.
    Type: Application
    Filed: December 11, 2000
    Publication date: September 20, 2001
    Applicant: Nycomed Imaging AS, a Oslo, Norway Corporation
    Inventors: Jo Klaveness, Bjorn Fuglass, Pal Rongved, Edvin Johannesen, Paul Mark Henrichs, Wolfgang Hans Heinrich Gunther, Edward Richard Bacon, John Luke Toner, Gregory Lynn McIntire, Vinay C. Desai
  • Light imaging contrast agents
    Patent number: 6159445
    Abstract: The present invention relates to the use of particulate materials as contrast agents in vivo light imaging.
    Type: Grant
    Filed: December 4, 1997
    Date of Patent: December 12, 2000
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Bjorn Fuglass, P.ang.al Rongved, Edvin Johannesen, Paul Mark Henrichs, Wolfgang Hans Heinrich, Edward Richard Bacon, John Luke Toner, Gregory Lynn McIntire, Vinay C. Desai
  • Polymeric contrast agents for medical imaging
    Patent number: 5801228
    Abstract: The invention provides polymeric polychelants containing polymer repeat units of formula ?L--Ch--L--B! (where Ch is a polydentate chelant moiety; L is an amide or ester linkage; B is a hydrophobic group providing a carbon chain of at least 4 carbon atoms between the L linkages it interconnects) or a salt or chelate thereof, with the proviso that where Ch is 2,5-biscarboxymethyl-2,5-diazahex-1,6-diyl, the polychelant is metallated with lanthanide or manganese ions or B provides a carbon chain of at least 10 carbon atoms between the L linkages it interconnects and their salts and chelates. The paramagnetic polychelates of the polychelants of the invention have remarkably high R.sub.1 relaxivities.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 1, 1998
    Assignee: Nycomed Imaging AS
    Inventors: Kenneth Robert Hollister, Kenneth Edmund Keller, Dong Wei, Xin Peng, David Lee Ladd, Paul Mark Henrichs, Robert Allen Snow