Patents by Inventor Paul Michael D'Agostino

Paul Michael D'Agostino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of dried synthetic prothrombin time reagents
    Patent number: 6183979
    Abstract: A method for preparation of an air-dried prothrombin time (PT) reagent which uses a recombinant protein and synthetic phospholipids is described. The source for the recombinant protein is rabbit brain, and the phospholipids employed are palmitoyloleoylphosphatidylcholine (POPC) and palmitoyloleoylphosphatidylserine (POPS). The particular formulation buffer used to dilute the lipidated tissue factor provides a reagent that is dried without lyophilization and remains stable for at least 2 weeks at 37 C. A method for preparing the improved PT reagent and a method of using the reagent to analyze blood PT is also provided.
    Type: Grant
    Filed: March 24, 1999
    Date of Patent: February 6, 2001
    Assignee: International Technidyne Corporation
    Inventors: Ted C. K. Lee, Paul Michael D'Agostino, Anne Jessica Gorman