Abstract: This invention relates to a monopod device for use with a phone, tablet, camera, and other recording devices that is supported by the monopod and is inserted into the ground to provide hands-free photographing, video recording, and streaming of music and video. The monopod device includes a magnetic mounting system for electronic devices, silicone covered threaded magnet, ferrous metal plate with adhesive, rotational adjustment mechanism, and non-collapsible support hollow shaft. The hollow shaft with a pointed plug is constructed to be inserted into the ground to provide stable hands-free filming and use of the electronic device. The rotational adjustment mechanism having a swivel secures the threaded magnet allows different filming and viewing angles. The threaded magnet provides powerful pulling power that allows coupling of small electronic devices. This invention has a cradle free design providing safe and easy one-handed device use. The invention provides a solution to filming sports motion.

Abstract: The invention concerns methods for early detection, monitoring and prognosis of a flavivirus-induced infection, comprising the detection of a complex formed by the flavivirus non-structural glycoprotein NS1 and plasma lipoprotein particles in a biological anti-NS1 Mab sample during the clinical phase of the infection.

Abstract: A micro device transfer tool and methods of operation are described. In an embodiment, the micro device transfer tool includes an articulating transfer head assembly capable of six degrees of motion. A miniatured camera assembly may be secured near the point of contact for the articulating transfer head assembly to aid in system alignment. In an embodiment, an encoder system is described for alignment of a micro pick up array and target substrate using complementary concentric grating patterns. In an embodiment a miniaturized position sensor design is described for sensing position of various system components during alignment or pick and place processes.

Abstract: The invention is a magnetic mounting apparatus for electronic devices used to film sports motion, personal content, and hands-free video and music streaming. The mounting apparatus includes a silicone coated threaded magnet, a clamp lined with a rubber mold, and an adjustable toggle latch locking clasp that allows attachment to rods or shafts of varying widths. The threaded magnet is of sufficient magnetic force to securely support the electronic device. Such electronic devices include and are not limited to smart phones, tablets, and cameras. A metal ferrous plate is attached to the electronic device with adhesive, thereby providing a secure magnetic connection between the mounting apparatus and electronic device.

Abstract: The present disclosure is directed to systems and methods for restoring custodian-based data. The method includes, for example, (i) receiving a request for restoring custodian-based data associated with multiple custodians; (ii) identifying, in a query index, one or more custodian actions associated with the multiple custodians based on the request; and (iii) generating data associated with the identified one or more custodian actions in a format indicated by the request. The one or more custodian actions correspond to one or more immutable identifiers.

Abstract: The present disclosure is directed to systems and methods for searching custodian-based data. The method includes, for example, retrieving custodian-based data associated with multiple custodians; retrieving immutable identifiers associated with one or more custodian actions associated with multiple custodians; generating a query index the custodian-based data at least based on the one or more custodian actions; and searching the custodian-based data based on the query index and the immutable identifiers. The query index can include one or more data items, and each of the data items of the query index is associated with one of the immutable identifiers.

Abstract: Disclosed are bispecific compounds (degraders) that target EP300/CBP for degradation. Also disclosed are pharmaceutical compositions containing the degraders and methods of using the compounds to treat disease.

Abstract: The present disclosure is directed to systems and methods for managing custodian-based data. The method includes, for example, (i) retrieving custodian-based data associated with multiple custodians; (ii) analyzing metadata items associated with the custodian-based data, and the metadata items includes one or more custodian actions; (iii) generating immutable identifiers for the custodian-based data associated with the custodian actions; and (iv) storing the custodian-based data in a raw data form. The method also enables a query of the custodian-based data based on the custodian actions.

Abstract: Provided herein are compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat diseases or disorders associated with HDAC3 activity.

Abstract: Computer-implemented method, tax return preparation systems and computer program products for presenting an explanation for a tax calculation or operation performed by a tax return preparation system when the system is in “forms” mode. An electronic version of a tax authority form that has been modified by inclusion of interface elements is displayed to a user. In response to the user selecting an interface element while in forms mode, presentation of an explanation regarding a tax calculation or operation for the associated field is invoked. The user interface controller provides data in response to selection of the interface element to an explanation engine, which determines an explanation based at least in part upon the tax calculation graph. The explanation is provided to the user interface controller for presentation to the user.

Abstract: A method for constructing a sub-blockchain in a blockchain system comprising a distributed network of nodes comprises generating and propagating, by one of the nodes, a candidate sub-block comprised in a sub-blockchain to be connected to one of main blocks included in a main blockchain; validating the candidate sub-block and storing and propagating the validated candidate sub-block by one of the nodes; validating a content block received from a node which generated the candidate sub-block corresponding to content queried by a user and storing and propagating an end block connected to the content block by one of the nodes; and if the number of the same end blocks received from other nodes is larger than a preconfigured value, generating an approved sub-block, and propagating the approved sub-block by one of the nodes while updating the approved sub-block to a local copy of a blockchain.

Abstract: Computer-implemented systems, methods and articles for generating an error report listing errors identified in the computerized preparation of a payroll tax form. The system includes a computing device, a data store, and a payroll tax form software application executable by the computing device. The payroll tax form software includes a payroll calculation engine, an error check engine, and one or more error graph(s). Each error graph includes a plurality of interconnected nodes configured to utilize tax data and calculated payroll data to identify errors. The calculation engine is configured to read tax data from the shared data store, perform payroll calculation operations, and write calculated payroll data to the shared data store. The error check engine is configured to read the tax data and payroll data and process the error graph(s) to identify errors and generate an error report listing the errors and/or explanations of the errors.

Abstract: A rotatable nacelle includes an engine inlet configured to receive air and an inlet air management system (IAMS). The IAMS includes a primary inlet configured to selectively allow air to flow into a duct associated with the engine air inlet via the primary inlet and a secondary inlet configured to selectively allow air to flow into the duct associated with the engine air inlet via the secondary inlet. The secondary inlet is configured to receive an air filter.

Abstract: Provided herein are bifunctional compounds that bind a target protein (e.g., a selected protein) and/or induce ubiquitination for degradation of the target protein. In particular, provided are compounds that bind a bromodomain or bromodomain-containing protein (e.g., BET proteins) or histone methyltransferases (HMTs, e.g., enhancer of zeste homolog 1 (EZH1), or FKBP12) and can promote its degradation by recruiting it to the ubiquitin receptor RPN13 (e.g., RA190), for proteasomal degradation. Also provided are pharmaceutical compositions comprising the bifunctional compounds, methods of treating and/or preventing diseases (e.g., proliferative diseases, cancers, benign neoplasms, pathological angiogenesis, inflammatory diseases, and autoimmune diseases) and musculoskeletal diseases, and methods of inducing the degradation of a target (e.g., a target protein) by recruiting it to the ubiquitin receptor RPN13 of the proteasome in a subject by administering a compound or composition described herein.

Abstract: An image processing method including: capturing changes in a monitored scene; and performing a sparse feature calculation on the changes in the monitored scene to obtain a sparse feature map.

Abstract: Structures and methods to actively control the shape of a micro pickup array (MPA) during micro device transfer are described. In an embodiment, a strain is applied to the MPA counteractive to strain arising during micro device transfer operations. For example, strain may be applied by a piezoelectric actuator element bonded to a back side of the base substrate to control a curvature of base substrate, and by extension the MPA.

Abstract: Computer-implemented method, tax return preparation systems and computer program products for presenting an explanation for a tax calculation or operation performed by a tax return preparation system when the system is in “forms” mode. An electronic version of a tax authority form that has been modified by inclusion of interface elements is displayed to a user. In response to the user selecting an interface element while in forms mode, presentation of an explanation regarding a tax calculation or operation for the associated field is invoked. The user interface controller provides data in response to selection of the interface element to an explanation engine, which determines an explanation based at least in part upon the tax calculation graph. The explanation is provided to the user interface controller for presentation to the user.

Abstract: A method for constructing a sub-blockchain in a blockchain system comprising a distributed network of nodes comprises generating and propagating, by one of the nodes, a candidate sub-block comprised in a sub-blockchain to be connected to one of main blocks included in a main blockchain; validating the candidate sub-block and storing and propagating the validated candidate sub-block by one of the nodes; validating a content block received from a node which generated the candidate sub-block corresponding to content queried by a user and storing and propagating an end block connected to the content block by one of the nodes; and if the number of the same end blocks received from other nodes is larger than a preconfigured value, generating an approved sub-block, and propagating the approved sub-block by one of the nodes while updating the approved sub-block to a local copy of a blockchain.

Abstract: Computer-implemented method, tax return preparation systems and computer program products for presenting an explanation for a tax calculation or operation performed by a tax return preparation system when the system is in “forms” mode. An electronic version of a tax authority form that has been modified by inclusion of interface elements is displayed to a user. In response to the user selecting an interface element while in forms mode, presentation of an explanation regarding a tax calculation or operation for the associated field is invoked. The user interface controller provides data in response to selection of the interface element to an explanation engine, which determines an explanation based at least in part upon the tax calculation graph. The explanation is provided to the user interface controller for presentation to the user.

Abstract: In a drilling system for drilling a borehole with drilling fluid, a flow loop communicates the drilling fluid, and a differential pressure device in the flow loop at a measurement location produces a pressure drop in flow. The measurement location can be between the borehole and a drilling choke or between a mud pump and the borehole. Piping diverts a portion of the flow at the measurement location so a flowmeter can measure the diverted flow portion. A processing unit receives a measured parameter from the flowmeter and determines a diverted flow rate of the diverted portion therefrom to correlate it to a value of the main flow rate through the flow loop at the measurement location.