Patents by Inventor Paul Pempsell
Paul Pempsell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8394326Abstract: A flow cytometer is provided which includes an interrogation flow cell and a plurality of assay fluidic lines extending into the interrogation flow cell. A method of operating such a flow cytometer includes priming the interrogation flow cell with a sheath fluid and injecting different assay fluids into a flow of the sheath fluid through the plurality of fluidic lines. A fluidic line assembly is provided which includes a plurality of capillary tubes coupled to a base section configured for coupling to an interrogation flow cell assembly of a flow cytometer. The capillary tubes are dimensionally configured such that when the fluidic line assembly is arranged within the flow cytometer and fluid is dispensed from one or more of the capillary tubes at a given pressure differential with respect to an encompassing sheath fluid within the interrogation flow cell the fluid is substantially centrally aligned within the interrogation flow cell.Type: GrantFiled: October 12, 2011Date of Patent: March 12, 2013Assignee: Luminex CorporationInventors: Jarden E. Krager, William R. Deicher, Adam Richard Schilffarth, Paul Pempsell, Wayne D. Roth
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Publication number: 20120183441Abstract: A fluid assay preparation and analysis system is provided which includes a pipette disposed above an assay plate receiving area, a magnet disposed below the assay plate receiving area in approximate alignment with the pipette, and an actuator configured to move the magnet proximate the assay plate receiving area. A method for preparing and analyzing an assay includes injecting a sample into a sample well of an assay preparation plate and inserting the assay preparation plate into a fluid assay analysis system. The method further includes mixing the sample with one or more reagents in an assay plate receiving area of the system and subsequently aspirating the prepared assay into an examination chamber of the system.Type: ApplicationFiled: February 14, 2012Publication date: July 19, 2012Applicant: Luminex CorporationInventors: Adam Richard Schilffarth, William Deicher, Paul Pempsell
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Publication number: 20120184037Abstract: A fluid assay preparation and analysis system is provided which includes a pipette disposed above an assay plate receiving area, a magnet disposed below the assay plate receiving area in approximate alignment with the pipette, and an actuator configured to move the magnet proximate the assay plate receiving area. A method for preparing and analyzing an assay includes injecting a sample into a sample well of an assay preparation plate and inserting the assay preparation plate into a fluid assay analysis system. The method further includes mixing the sample with one or more reagents in an assay plate receiving area of the system and subsequently aspirating the prepared assay into an examination chamber of the system.Type: ApplicationFiled: February 14, 2012Publication date: July 19, 2012Applicant: Luminex CorporationInventors: Adam Schilffarth, William Deicher, Paul Pempsell
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Publication number: 20120028366Abstract: A flow cytometer is provided which includes an interrogation flow cell and a plurality of assay fluidic lines extending into the interrogation flow cell. A method of operating such a flow cytometer includes priming the interrogation flow cell with a sheath fluid and injecting different assay fluids into a flow of the sheath fluid through the plurality of fluidic lines. A fluidic line assembly is provided which includes a plurality of capillary tubes coupled to a base section configured for coupling to an interrogation flow cell assembly of a flow cytometer. The capillary tubes are dimensionally configured such that when the fluidic line assembly is arranged within the flow cytometer and fluid is dispensed from one or more of the capillary tubes at a given pressure differential with respect to an encompassing sheath fluid within the interrogation flow cell the fluid is substantially centrally aligned within the interrogation flow cell.Type: ApplicationFiled: October 12, 2011Publication date: February 2, 2012Applicant: LUMINEX CORPORATIONInventors: Jarden E. Krager, William R. Deicher, Adam Richard Schilffarth, Paul Pempsell, Wayne D. Roth
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Patent number: 8062609Abstract: A flow cytometer is provided which includes an interrogation flow cell and a plurality of assay fluidic lines extending into the interrogation flow cell. A method of operating such a flow cytometer includes priming the interrogation flow cell with a sheath fluid and injecting different assay fluids into a flow of the sheath fluid through the plurality of fluidic lines. A fluidic line assembly is provided which includes a plurality of capillary tubes coupled to a base section configured for coupling to an interrogation flow cell assembly of a flow cytometer. The capillary tubes are dimensionally configured such that when the fluidic line assembly is arranged within the flow cytometer and fluid is dispensed from one or more of the capillary tubes at a given pressure differential with respect to an encompassing sheath fluid within the interrogation flow cell the fluid is substantially centrally aligned within the interrogation flow cell.Type: GrantFiled: November 12, 2007Date of Patent: November 22, 2011Assignee: Luminex CorporationInventors: Jarden E. Krager, William R. Deicher, Adam Richard Schilffarth, Paul Pempsell, Wayne D. Roth
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Publication number: 20090191638Abstract: Assay preparation plates are provided which include an array of wells, a magnet, and an actuator configured to move the magnet proximate and remote relative to the array. A fluid assay preparation and analysis system is provided which includes a pipette disposed above an assay plate receiving area, a magnet disposed below the assay plate receiving area in approximate alignment with the pipette, and an actuator configured to move the magnet proximate the assay plate receiving area. A method for preparing and analyzing an assay includes injecting a sample into a sample well of an assay preparation plate and inserting the assay preparation plate into a fluid assay analysis system. The method further includes mixing the sample with one or more reagents in an assay plate receiving area of the system and subsequently aspirating the prepared assay into an examination chamber of the system.Type: ApplicationFiled: January 26, 2009Publication date: July 30, 2009Applicant: LUMINEX CORPORATIONInventors: Adam Schilffarth, William Deicher, Paul Pempsell
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Publication number: 20080113447Abstract: A flow cytometer is provided which includes an interrogation flow cell and a plurality of assay fluidic lines extending into the interrogation flow cell. A method of operating such a flow cytometer includes priming the interrogation flow cell with a sheath fluid and injecting different assay fluids into a flow of the sheath fluid through the plurality of fluidic lines. A fluidic line assembly is provided which includes a plurality of capillary tubes coupled to a base section configured for coupling to an interrogation flow cell assembly of a flow cytometer. The capillary tubes are dimensionally configured such that when the fluidic line assembly is arranged within the flow cytometer and fluid is dispensed from one or more of the capillary tubes at a given pressure differential with respect to an encompassing sheath fluid within the interrogation flow cell the fluid is substantially centrally aligned within the interrogation flow cell.Type: ApplicationFiled: November 12, 2007Publication date: May 15, 2008Applicant: LUMINEX CORPORATIONInventors: Jarden E. Krager, William R. Deicher, Adam Richard Schilffarth, Paul Pempsell, Wayne D. Roth
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Publication number: 20080075636Abstract: A fluid assay preparation system is provided which includes a reusable reaction apparatus and a plurality of fluidic lines coupled to the reusable reaction apparatus. The reusable reaction apparatus includes a process vessel with a tapered floor and the fluidic lines extend into the process vessel a distance less than approximately 1.0 mm from a bottommost surface of the tapered floor. Inner and outer surfaces of the fluidic lines and an inner surface of the process vessel may include one or more materials having a coefficient of friction less than or equal to approximately 0.1 relative to polished steel. The system further includes an assembly of one or more pumps, one or more valves, and control electronics collectively configured to pass reagents to the process vessel. Methods and storage mediums having program instructions configured to prepare fluid assays using such a system are also provided.Type: ApplicationFiled: September 20, 2007Publication date: March 27, 2008Applicant: LUMINEX CORPORATIONInventors: Adam Richard Schilffarth, William R. Deicher, Paul Pempsell
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Publication number: 20060105395Abstract: Various methods and systems for positioning microspheres for imaging are provided. One system includes a filter medium that includes openings. The openings are spaced in a substantially equidistant manner across the filter medium. The system also includes a flow subsystem coupled to the filter medium. The flow subsystem is configured to exert a force on the microspheres such that the microspheres are positioned above the openings. A method for positioning microspheres for imaging includes exerting a force on the microspheres through a filter medium such that the microspheres are positioned above openings in the filter medium. The openings are spaced as described above.Type: ApplicationFiled: November 9, 2005Publication date: May 18, 2006Inventor: Paul Pempsell