Patents by Inventor Paul Polakis

Paul Polakis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF
    Publication number: 20220298161
    Abstract: Conjugates and compounds for making conjugates which are PBD molecules linked via the N10 position are disclosed, along with the use of the conjugates for treating proliferative diseases, including cancer.
    Type: Application
    Filed: January 27, 2022
    Publication date: September 22, 2022
    Inventors: Philip Wilson HOWARD, Luke MASTERSON, Arnaud TIBERGHIEN, John A. FLYGARE, Janet L. GUNZNER, Paul POLAKIS, Andrew POLSON, Helga E. RAAB, Susan D. SPENCER
  • Anti-B7-H4 Antibodies and Immunoconjugates
    Publication number: 20220251213
    Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: February 22, 2022
    Publication date: August 11, 2022
    Applicant: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
    Publication number: 20220204640
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: March 16, 2022
    Publication date: June 30, 2022
    Applicant: Genentech, Inc.
    Inventors: Mark Dennis, Bonnee Rubinfeld, Paul Polakis
  • Anti-B7-H4 Antibodies and Immunoconjugates
    Publication number: 20220162318
    Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: December 10, 2021
    Publication date: May 26, 2022
    Applicant: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • Anti-B7-H4 antibodies and immunoconjugates
    Patent number: 11286302
    Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: March 29, 2022
    Assignee: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • Anti-B7-H4 antibodies and immunoconjugates
    Patent number: 11230600
    Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: January 25, 2022
    Assignee: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • Anti-Ly6E antibodies and methods of use
    Patent number: 10889651
    Abstract: The invention provides anti-Ly6E antibodies, immunoconjugates and methods of using the same.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: January 12, 2021
    Assignee: Genentech, Inc.
    Inventors: Jyoti Asundi, Ron Firestein, Paul Polakis, Chie Sakanaka, Peter Chang, Rayna Takaki Venook
  • Anti-B7-H4 Antibodies and Immunoconjugates
    Publication number: 20190241663
    Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: October 22, 2018
    Publication date: August 8, 2019
    Applicant: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • ANTI-Ly6E ANTIBODIES AND METHODS OF USE
    Publication number: 20190085089
    Abstract: The invention provides anti-Ly6E antibodies, immunoconjugates and methods of using the same.
    Type: Application
    Filed: July 31, 2018
    Publication date: March 21, 2019
    Applicant: Genentech, Inc.
    Inventors: Jyoti Asundi, Ron Firestein, Paul Polakis, Chie Sakanaka, Peter Chang, Rayna Takaki Venook
  • ANTI-B7-H4 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20190062432
    Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: July 24, 2018
    Publication date: February 28, 2019
    Applicant: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • Anti-PMEL17 antibodies and immunoconjugates
    Patent number: 10196454
    Abstract: The invention provides anti-PMEL17 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: February 5, 2019
    Assignee: Genentech, Inc.
    Inventors: Youjun Chen, William Mallet, Paul Polakis, Christine Tan, Jyoti Asundi, Suzanna Clark
  • Anti-B7-H4 antibodies and immunoconjugates
    Patent number: 10150813
    Abstract: The disclosure provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: December 11, 2018
    Assignee: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
    Publication number: 20180344864
    Abstract: The invention is directed to antibody drug conjugate compositions of matter useful for the diagnosis and treatment of tumors in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: December 18, 2017
    Publication date: December 6, 2018
    Applicant: Genentech, Inc.
    Inventors: Mark DENNIS, William MALLET, Paul POLAKIS
  • ANTI-GPC3 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20180312602
    Abstract: The invention provides anti-GPC3 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: March 7, 2018
    Publication date: November 1, 2018
    Applicant: GENENTECH, INC.
    Inventors: Paul Polakis, Youjun Chen
  • COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
    Publication number: 20180251567
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: May 18, 2018
    Publication date: September 6, 2018
    Applicant: Genentech, Inc.
    Inventors: Mark Dennis, Bonnee Rubinfeld, Paul Polakis
  • Anti-Ly6E antibodies and methods of use
    Patent number: 10066022
    Abstract: The invention provides anti-Ly6E antibodies, immunoconjugates and methods of using the same. In some embodiments, the anti-Ly6E antibodies comprise heavy chain HVRs comprising the amino acid sequences of SEQ ID NOs: 32-34 and/or light chain HVRs comprising the amino acid sequences of SEQ ID NOs: 29-31.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: September 4, 2018
    Assignee: Genentech, Inc.
    Inventors: Jyoti Asundi, Ron Firestein, Paul Polakis, Chie Sakanaka, Peter Chang, Rayna Takaki Venook
  • Anti-B7-H4 antibodies and immunoconjugates
    Patent number: 10059768
    Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: August 28, 2018
    Assignee: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • Antibodies and immunoconjugates
    Patent number: 10017577
    Abstract: The invention provides immunoconjugates and methods of using the same.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: July 10, 2018
    Assignee: Genentech, Inc.
    Inventors: Paul Polakis, Peter Dragovich, Thomas Harden Pillow, Shang-Fan Yu
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20180169259
    Abstract: The invention provides anti-CD79b antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: June 21, 2017
    Publication date: June 21, 2018
    Applicant: Genentech Inc.
    Inventors: Paul Polakis, Andrew Polson, Susan Diane Spencer, Shang-Fan Yu
  • Compositions and methods for the diagnosis and treatment of tumor
    Patent number: RE47223
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: February 5, 2019
    Assignee: GENENTECH, INC.
    Inventors: Mark S. Dennis, Paul Polakis, William Mallet